Kids gain weight on certain meds Oct 30, 2009
7 pounds, weight gain was lowest with aripiprazole (Abilify) ... At present, the FDA has approved only two drugs, risperidone and aripiprazole, for use in children; both are approved to treat schizophrenia and bipolar disorder, and risperidone is also approved for "irritability associated with autistic disorder.". (CNN)
Use Of Antipsychotic Medications By Children And Adolescents Associated With Significant Weight Gain Oct 30, 2009
Patients were treated with the antipsychotic medications aripiprazole, olanzapine, quetiapine, or risperidone for 12 weeks ... with aripiprazole (n = 41) compared with minimal weight change of 0 ... "With risperidone, levels of triglycerides increased significantly. Metabolic baseline-to-end-point changes were not significant with aripiprazole or in the untreated comparison group. Patients receiving quetiapine had modestly higher incidence rates of hyperglycemia and the metabolic syndrome and... (Science Daily)
Antipsychotics Cause Rapid Weight Gain in Youth Oct 29, 2009
The study looked at four of the most common antipsychotic drugs used in children -- Johnson on's Risperdal or risperidone, Eli Lilly's Zyprexa or olanzapine, Bristol-Myers Squibb's Abilify or aripiprazole and AstraZeneca's Seroquel or quetiapine. A team led by Dr. Christoph Correll of Zucker Hillside Hospital and the Feinstein Institute for Medical Research in New York studied 272 children and teens aged 4 to 19 with bipolar disorder, schizophrenia and disruptive or aggressive behavior spectrum... (Newsmax)
Antipsychotic Drugs Spur Dramatic Weight Gain in Kids Oct 28, 2009
The study focused on four antipsychotics commonly prescribed to children: aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel) and risperidone (Risperdal). After nearly 11 weeks, the treated kids gained an average of 18. (Atlanta Journal-Constitution -- Health)
Most Newer Antipsychotics No Better Than Older Ones, Just Different Feb 7, 2009
But, other second generation drugs, such as aripiprazole (Abilify), quetiapine (Seroquel), sertindole (Serdolect), ziprasidone (Geodon) and zotepine (Nipolept), were no more effective than first-generation drugs, the researchers reported. And, only aripiprazole and ziprasidone among the second-generation drugs did not induce more weight gain than the first-generation drug haloperidol (Haldol), the study found. (MEDLINEplus)
