Fructose Tied to Higher Blood Pressure Sep 25, 2009
It also found that the drug allopurinol, used to treat gout, can alleviate the effect by reducing uric acid levels in the body ... Half the men were also given allopurinol ... The men who did not get allopurinol also were twice as likely to develop metabolic syndrome, measured by risk factors such as too much abdominal fat, high blood pressure and poor cholesterol readings. (MEDLINEplus)
American Heart Association Meeting Report: High-Sugar Diet Increases Men's Blood Pressure; Gout Drug Protective Sep 24, 2009
Half of the men were randomly assigned to get the gout drug allopurinol and the other half acted as controls ... In contrast, men on the high-fructose diet plus allopurinol had significantly lower uric acid levels and virtually no increase in systolic blood pressure (only 1 mm Hg) ... Among men consuming fructose plus allopurinol, virtually no change in the rate of metabolic syndrome occurred -- perhaps because the gout drug prevented the blood pressure rise associated with increased fructose... (PR Newswire)
Cephalon warns of drug combination Apr 29, 2009
Following patient death, Cephalon warns of using Treanda with allopurinol - Philadelphia Business Journal ... Following patient death, Cephalon warns of using Treanda with allopurinol ... is updating the prescribing information for its cancer treatment drug Treanda to include a warning about the use of the drug with allopurinol, according to documents filed with the Securities and Exchange Commission on Tuesday. (Philadelphia Business Journal, PA)
* World News Quick Take Mar 9, 2009
All five victims had been treated with Allopurinol, produced by Manufacturer Europharm Laboratories. The drug had been contaminated by a fungus known as Rhizopus microsporus. (Taipei Times, Taiwan -- World Business)
Understanding Gout Feb 27, 2009
Treatment of recurrent attacks includes modifications in diet as well as the use of medications like Allopurinol, (which inhibits formation of uric acid) and Probenecid and Sulfinpyrazone that are used to increase the output of uric acid by the kidney. Dosing and combination therapy depends upon the level of serum uric acid which must be measured periodically during therapy. (Suite101.com)
FDA OKs New Gout Drug Uloric Feb 17, 2009
In 2005, the FDA refused to approve Uloric because there were slightly more deaths and heart problems in patients taking the drug than in patients taking allopurinol, another gout drug ... The new study found no more deaths and no more heart problems in patients taking Uloric than in patients taking allopurinol. (WebMD)
Takeda Wins U.S. Approval for Uloric, First New Gout Treatment in 40 Years Feb 15, 2009
Takeda tested its drug against generic allopurinol, the most commonly prescribed treatment to lower levels of uric acid in the blood. While allopurinol was approved by the FDA in 1966 for use in a range of doses, concerns that the drug may cause rashes or a deadly skin reaction have discouraged doctors from using the highest, most effective doses, according to released by Takeda before the advisory panel meeting. (Bloomberg -- Asia)
Takeda wins FDA approval for Uloric Feb 15, 2009
Last Updated: Sunday 15 February 2009 14:15 HRS. by - February 15, 2009 - 0 comments. (The Money Times)
FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout Feb 14, 2009
The largest, pivotal, phase 3 clinical trial, CONFIRMS, demonstrated that ULORIC 80 mg was superior to ULORIC 40 mg and allopurinol 300/200 mg (67 percent, 45 percent and 42 percent, respectively) at achieving the primary end point of serum uric acid less than 6 ... 74 per 100 patient-years) than allopurinol (0. (PR Newswire)
