DNA damage induced by cis- and carboplatin as indicator for in vitro sensitivity of ovarian carcinoma cells Oct 11, 2009
In contrast to the platinum compounds the correlation of DNA damage and cytotoxicity induced by adriamycin was low (r = 0,692) or did not exist for gemcitabin. Conclusions. (BioMed Central)
'American Idol' Contestant Josiah Leming's Mother Dies Jun 18, 2009
" Though he failed to make the Top 24, Leming was one of the show's most popular contestants, and in March 2008 he (In October, he released his debut EP, Angels Undercover, on which he sang about Sharon's battle with the disease. Sharon Leming that documented her condition and her lengthy struggle with leiomyosarcoma. By her own count, she underwent "17 surgeries, 55 radiation treatments, 6 cycles of Gemzar/Taxotere, 1 cycle of AIM, 3 cycles of Adriamycin and 6 cycles of Yondelis" to cure the... (VHI.com -- Music News)
Telik Reports Preclinical Results at AACR Annual Meeting Apr 29, 2009
TLK58747 inhibited the growth of nine established cell lines of various tumor types and retained its effectiveness against cancer cell lines resistant to standard cancer chemotherapeutics including adriamycin, paclitaxel, and carboplatin. Treatment of human cancer cells with TLK58747 led to the activation of the DNA damage-response pathway, and produced G2/M cell cycle arrest in human solid tumor cell lines. (PR Newswire)
* Oxygen therapy is valuable, sometimes Mar 17, 2009
Also, the therapy is clearly dangerous for some patients, including those with a collapsed lung and those receiving chemotherapy with cisplatinum or adriamycin. The therapy may also be hazardous for pregnant women and people with poorly controlled asthma or active cancer, among others. (Taipei Times, Taiwan -- Business)
Genes May Predict Lymphoma Treatment Outcome Feb 7, 2009
The standard treatment for DLBCL is a combination five drugs -- cyclophosphamide, hydroxydoxorubicin (doxorubicin, Adriamycin), Oncovin (vincristine), prednisone and rituximab. Known as R-CHOP, this treatment cures up to 60 percent of patients. (MEDLINEplus)
