Obama recuerda a los muertos de Fort Hoo... Nov 11, 2009
"Ninguna fe justifica estos actos asesinos y cobardes. Ningn Dios justo y amoroso los ve con favor", dijo Obama a la multitud en una clida tarde en Texas. "Y por lo que l ha hecho, sabemos que el asesino se topar con la justicia, en este mundo y en el prximo". (San Diego Union-Tribune)
Zhou Seeks to Deflect European, Japanese Appeals for Yuan to Strengthen Nov 8, 2009
maker of the worlds best-selling diabetes drug, Actos, last month cut its revenue outlook because of the stronger yen. Turning the Screws. (Bloomberg -- Asia)
Takeda, Amylin in deal Nov 3, 2009
The purchase may help Takeda buffer losses after Actos, its top seller with $4 billion generated for the year ended March 31, loses patent protection in January 2011 ... Still, this drug alone won t be enough to make up for the sales decline in Actos, and the company needs to make more acquisitions. (Boston Globe)
Takeda, Amylin to Develop Obesity Drugs in Possible $1 Billion Agreement Nov 2, 2009
The purchase may help Takeda buffer losses after Actos, its best seller with $4 billion generated for the year ended March 31, loses patent protection in January 2011. The drugmaker needs products to replace sales lost when approval for a combination diabetes treatment that includes Actos was delayed by U.S. regulators ... Still, this drug alone wont be enough to make up for the sales decline in Actos, and the company needs to make more acquisitions. (Bloomberg -- Japan)
Takeda First-Half Profit Jumps, Beats Analysts' Estimates on Lower Costs Oct 31, 2009
Oct. 30 (Bloomberg) -- , maker of the worlds best-selling diabetes drug Actos, posted first-half profit that more than doubled on lower expenses, while cutting its revenue outlook because of weaker sales and the stronger yen ... Takeda has set up more overseas sales offices including in Mexico and hired an external advisory board as part of efforts to counter an anticipated decline in revenue from its two best- selling products, Actos and Prevacid ... Patent protection will expire next month... (Bloomberg -- Asia)
Cancer Alert Explored as Sanofi, Novo Diabetes Drugs Scrutinized in Vienna Sep 30, 2009
Diabetes therapies metformin, Avandia and Actos may be protective against malignancies, Gale said ... Gale said there is evidence to suggest the pill, now available in generic formulations, as well as newer drugs like Avandia and Takeda Pharmaceuticals Co.s Actos, known as glitazones, may protect patients against cancer. (Bloomberg -- UK)
Takeda Receives FDA Complete Response Letter for the Investigational Fixed-Dose Combination of alogliptin and ACTOS(R) (pioglitazone HCl) for the Treatment of Type 2 Diabetes Sep 4, 2009
and OSAKA, Japan, Sept. 4 /PRNewswire/ -- Takeda Pharmaceutical Company Limited ("Takeda") today announced that its wholly owned subsidiary, Takeda Global Research & Development Center, Inc. (U.S.), received on September 2 (U.S. TIME), a complete response letter from the U.S. Food and Drug Administration (FDA) regarding the New Drug Application (NDA) for the fixed-dose combination (FDC) of alogliptin and ACTOS(R) (pioglitazone HCl) ... "This complete response letter from the FDA is consistent... (PR Newswire)
Mundo Hispánico Sep 3, 2009
Ha desencadenado actos discriminatorios. programas de educacin sexual. (Atlanta Journal-Constitution -- Business)
Avandia Raises Heart Failure Risk More Than Actos Aug 20, 2009
TUESDAY, Aug. 18 (HealthDay News) -- The type 2 diabetes drug Avandia (rosiglitazone) increases the risk of heart failure and death more than another drug in the same class, Actos (pioglitazone), new Canadian research contends ... There is increasing evidence that Actos is safer than Avandia, Juurlink said ... Both Avandia and Actos belong to a class of drugs called thiazolidinediones, which are used widely to lower blood sugar in people with type 2 diabetes. (MEDLINEplus)
Glaxo's Diabetes Drug Avandia Has More Heart Risks Than Actos, Study Finds Aug 19, 2009
Glaxos Avandia Has More Heart Risks Than Actos, Study Finds - Bloomberg ... Glaxos Avandia Has More Heart Risks Than Actos, Study Finds ... Aug. 19 (Bloomberg) -- Patients taking s diabetes drug Avandia are more likely to develop heart failure or die than those on s rival medication, Actos, a Canadian review of health records found. (Bloomberg -- Europe)
Drug Cuts Diabetics' Pancreatic Cancer Risk Aug 4, 2009
The study, however, was too small to find a benefit for people who had taken another popular type of insulin sensitizing drug in a class called thiazolidinediones, which include GlaxoSmithKline's rosiglitazone or Avandia and Takeda Pharmaceutical's pioglitazone or Actos. Li said the study needs to be repeated in a bigger group of diabetics but added: "Our findings show metformin's potential as a chemopreventive agent.". (MEDLINEplus)
Takeda Leads Japan Drugmakers' Revenue Drop as Stronger Yen Hurts Earnings Aug 1, 2009
Sales of Takedas top four products, including Actos and heartburn pill Prevacid, fell when converted to yen, he said. The U.S. currency averaged 97. (Bloomberg -- Japan)
Takeda Says FDA Extended Review Deadline for New Diabetes Drug to Sept. 4 Jul 23, 2009
The FDA will now review the drug combining Takedas alogliptin and Actos diabetes medications by Sept. 4, Takeda said in a statement to the Tokyo Stock Exchange today. The original deadline was July 22. (Bloomberg -- Japan)
Takeda Provides Update on the Investigational Fixed-Dose Combination of alogliptin and ACTOS(R) (pioglitazone HCl) Jul 23, 2009
July 22, and OSAKA, Japan, July 23 /PRNewswire/ -- Takeda Pharmaceutical Company Limited ("Takeda") today announced that Takeda Global Research & Development Center, Inc., a wholly owned United States (U.S.) subsidiary, received notification from the U.S. Food and Drug Administration (FDA) that the FDA extended the review of the New Drug Application (NDA) for the fixed-dose combination (FDC) of alogliptin and ACTOS((R)) (pioglitazone HCl) ... The NDA for the FDC of alogliptin and ACTOS was... (PR Newswire)
The best treatment might be wrong for you Jul 23, 2009
Metformin is older and cheaper than many other drugs, but it matches or outperforms the newer thiazolidinediones (Actos, Avandia), according to a new review ... If you have high cholesterol: Avoid Avandia and Actos, which can raise "bad" LDL cholesterol and worsen congestive heart failure, according to AHRQ reports. (MSNBC -- Health)
Services today at NHS for 16-year-old Sofia Palma Jul 14, 2009
wrote on Jul 11, 2009 10:04 PM:" pues tragicamente ocurrio esta desgracia y lamentablemente tenemos que vivir con consecuencias de nuestros actos , espero que el no sea condenado por lo que hizo pero si debe ser reprendido por lo que hizo , y pues una vez mas se comprueba que los juveniles que no tienen a cristo en su corazon , perecen sin el . y pues que Dios tenga misericordia de raul . ". resident wrote on Jul 11, 2009 7:56 PM:" I think that the owner of the gun is living in the United States... (Nogales International, AZ)
Sanofi Drug's Cancer Risk Should Be Urgently Studied, Diabetes Group Says Jun 27, 2009
The French drugmaker said in February 2008 it aimed to make the medicine the worlds top diabetes treatment by 2015, overtaking Takeda Pharmaceutical Co.s Actos. Lantus, the worlds No. 1 insulin, takes second place to Actos in the $23 billion diabetes market. (Bloomberg -- Europe)
Genetic Markers To Help Fight Diabetes Discovered Jun 25, 2009
"We identified genetic variants that may predict how well someone will respond to the common anti-diabetes drug, Actos," said Dr. DiStefano, Director of TGen s Diabetes, Cardiovascular & Metabolic Diseases Division ... A TGen-led team, working with scientists from the University of Southern California s Keck School of Medicine, investigated why as many as 30-40 percent of diabetes patients treated with thiazolidinediones (TZDs), such as Actos, fail to respond to the drug with the expected... (Science Daily)
GSK: RECORD trial results do not change Avandias CV risk stigma, bone fracture risk, physicians say Jun 19, 2009
With the exception of congestive heart failure, the potential increased cardiovascular risk has not been demonstrated in meta-analyses and observational studies for Actos (pioglitazone), Williams noted, referring to Takedas TZD. He cited a retrospective study conducted at Henry Ford Hospital that demonstrated that Actos appeared have a lower risk of congestive heart failure and coronary heart disease events when compared to Avandia. Williams explained that while there has not been a... (FT.com -- Markets)
Avandia Raises Risk of Heart Failure, Fractures Jun 16, 2009
But Lavie added that many physicians are waiting for the results of another trial, known as TIDE, which compares Avandia with Actos, another drug in the same class. "Until then, I suspect that not much will change -- both drugs are contraindicated in heart failure and I doubt that this trial will lead the societies to change their recommendations that were based on many trials," he said. (MEDLINEplus)
New Diabetes Drug Shows Promise In Trial Jun 16, 2009
In the 16-week trial, 332 patients with type 2 diabetes received either once-daily doses of aleglitazar (at varying doses), the diabetes drug pioglitazone (Actos), or a placebo. At lower doses, aleglitazar appeared safe and effective, with less incidence of heart failure or edema than either Actos or placebo; it produced less weight gain than Actos when given at the 150-microgram dose. (MEDLINEplus)
Diabetes drug shows promise against multiple sclerosis May 27, 2009
In a small, double-blinded clinical trial, patients with relapsing remitting multiple sclerosis were assigned to take pioglitazone (a drug commercially known as Actos used to treat type-2 diabetes) or a placebo. Patients continued their normal course of therapy during the trial. (EurekAlert!)
FOCUS ON SENIORS: Many reasons why legs, feet swell May 4, 2009
Medications: Anti-inflammatory medicines for arthritis, steroids, blood pressure medicines such as amlodipine and nifedipine, estrogen, and the diabetes medicines rosiglitazone (Avandia) and pioglitazone (Actos), are frequent offenders for edema. Simple causes: Having a sedentary job or eating too much salt, also can cause mild swelling. (Florida Today)
Halting Avandia Use Hikes Blood Sugar Levels Apr 18, 2009
This study reaffirms that patients who discontinue use of rosiglitazone and another thiazolidinedione (TZD) called pioglitazone (Actos) are at increased risk for higher fasting blood glucose and hemoglobin A1c levels, which may increase their cardiovascular risk, cardiologists Dr. Stuart Zarich of Yale Medical School and Dr. Richard Nesto of the Lahey Clinic, wrote in an accompanying journal editorial. HealthDay. (MEDLINEplus)
Diabetes Drug Class Linked To Vision-Threatening Complication Apr 13, 2009
Fluid retention from heart failure or other diseases can worsen DME. Most of the glitazone users in the study were taking pioglitazone (Actos). Other studies have linked rosiglitazone (Avandia) the only other approved glitazone drug to a possible increase in the risk of myocardial infarction. (Science Daily)
Diabetics risking life and limb Apr 13, 2009
Actos (reduces insulin resistance): $222. 38. (MSNBC -- Health)
Economic woes leave diabetics skimping on care, risking lives Apr 13, 2009
33 metformin (helps control blood sugar): $4 Actos (reduces insulin resistance): $222. 38 1 lancet/day: $3. (USA Today -- News)
Certain Diabetes Drugs May Pose Eye Risk Apr 9, 2009
Use of Avandia, Actos tied to a retinal disorder, study finds ... Glitazones are a newer class of diabetes drugs that includes medicines such as pioglitazone (Actos) and rosiglitazone (Avandia). (MEDLINEplus)
Takeda to Move R&D Base to Chicago From Osaka as It Seeks Actos Successor Apr 1, 2009
March 31 (Bloomberg) -- , Japans biggest drugmaker, will move its research and development base to the Chicago area from Osaka as it seeks to release new products before the patent on its best-selling Actos treatment expires ... Takeda faces a potential sales decline when Actos, which generates a quarter of revenue, loses its patent protection in January 2011. (Bloomberg -- Japan)
Obama inicia campaña política legislativa Mar 26, 2009
Al anochecer, Obama particip; en dos actos para recaudar fondos en Washington los cuales podr;an significar un ingreso de unos 3 millones de d;lares para el Comit; Nacional Dem;crata. El partido se esfuerza para mantener el ritmo con sus hom;logos republicanos pese a haber resultado triunfantes en las recientes elecciones que les dio la Casa Blanca y un mayor poder en el Congreso. (OregonLive, OR -- News)
Japan's Topix Index Rises in Longest Streak in 4 Years on Dividend Demand Mar 25, 2009
3 percent to 3,770 yen after Japans largest drugmaker said combination treatment of its diabetes drug Actos and insulin product was approved by Japans health ministry. Nikkei futures expiring in June added 0. (Bloomberg -- Japan)
Takeda Falls Most Since 1987 on Concerns of U.S. Delay for Diabetes Drug Mar 9, 2009
March 9 (Bloomberg) -- fell the most in 21 years on concern U.S. approval of its diabetes drug alogliptin, a successor to its bestselling Actos, may be delayed ... The second such delay for alogliptin means it probably wont hit the market until after Actos loses patent protection in January 2011, , an analyst in Tokyo at KBC Securities, said ... The Actos expiration will become extremely painful with no offsetting revenue likely to be available at the time, Hall wrote in a note to clients... (Bloomberg -- Japan)
Chiquita quiere anular demanda por muertes en Colombia Feb 28, 2009
Los abogados de Chiquita insistieron que el dinero que pag; por siete a;os a las Autodefensas Unidas de Colombia no ten;a relaci;n directa con las matanzas, asesinatos, secuestros y actos de intimidaci;n cometidos por el grupo en las regiones productoras de pl;tano. "No hay se;alamientos de que Chiquita estuviera directamente involucrada en cualquiera de esos hechos", dijo Gregg Levy, abogado de Chiquita, con sede en Cincinnati. (OregonLive, OR -- News)
UBS pagará 780 millones; abrirá registros secretos de banco suizo Feb 19, 2009
"La confidencialidad de los clientes, a la que se comprometi; UBS, nunca tuvo la intenci;n de solapar actos fraudulentos ni la identidad de los clientes que, con la ayuda activa de personal del banco, hicieron un mal uso de estas medidas de protecci;n", agreg; el directivo el mi;rcoles. Aproximadamente 17. (OregonLive, OR -- Business)
Takeda wins FDA approval for Uloric Feb 15, 2009
Last Updated: Sunday 15 February 2009 14:15 HRS. by - February 15, 2009 - 0 comments. (The Money Times)
Avandia's Heart Risk Higher than Others in Its Class Feb 7, 2009
A similar diabetes drug, Actos, doesn't seem to carry same dangers, study finds ... MONDAY, Nov. 24 (HealthDay News) -- The widely used diabetes drug Avandia -- already controversial because of cardiovascular side effects -- may be riskier than Actos, another drug in the same class, researchers reported Monday ... The risk of heart failure and death for older diabetics appears greater with Avandia (rosiglitazone) than with Actos (pioglitazone), both of which are part of a class of drugs called... (MEDLINEplus)
2 Diabetes Drugs Double Fracture Risk in Women Feb 7, 2009
Both Avandia and Actos lower bone density, new analysis shows ... WEDNESDAY, Dec. 10 (HealthDay News) -- Two widely prescribed diabetes drugs, Avandia and Actos, double the risk of fractures in women but not in men, a new British analysis finds ... Avandia (rosiglitazone) and Actos (pioglitazone) are used to lower blood sugar in patients with type 2 diabetes. (MEDLINEplus)
