Carvedilol shown to have unique characteristics among beta blockers Nov 21, 2009
This observation suggests that the use of carvedilol in combination with inhibitors of angiotensin-converting enzyme (ACE inhibitors) may be of the greatest benefit to cardiac patients, and has significant clinical implications on which beta-blockers patients should take. "I think this is really good stuff," Xiang says. (EurekAlert!)
Heart Failure Drug May Help More in Higher Doses Nov 19, 2009
Study finds increase lowers chance of hospitalization or death. Tuesday, November 17, 2009. (MEDLINEplus)
With ARBs, a bigger dose is better for heart failure patients Nov 18, 2009
But many patients can't take ACE inhibitors because of side effects. Those patients are routinely given ARBs. (USA Today -- News)
Bundling Two Low-cost Heart Drugs Prevents Heart Attack And Stroke In Large, Diverse Population Oct 28, 2009
"We have long known from clinical trials that aspirin, cholesterol-lowering therapies such as statins, and ACE inhibitors such as lisinopril reduce the risk of future heart attacks and strokes in patients who have had a prior cardiovascular event or who have diabetes. Our primary goal here was to increase the use of the drugs," said study co-author Jim Bellows, Ph. D., Kaiser Permanente Care Management Institute's director of the Center for Evaluation and Innovation. (Science Daily)
Adding Drug Doesn't Help Control Blood Pressure Oct 27, 2009
ARBs, which have become increasingly popular in recent years, tend be more expensive, since many ACE inhibitors are available as generic drugs while ARBs generally are not ... ACE inhibitors attempt to prevent formation of angiotensin II, while ARBs block the cell receptors through which they act ... "There was some uncertainty about the effectiveness, benefits and harms of ACE inhibitors versus ARBs in this population" (people with known but stable heart disease), she said. (MEDLINEplus)
Micardis Given Wider Approval Oct 21, 2009
MONDAY, Oct. 19 (HealthDay News) -- Micardis (telmisartan) has received expanded approval from the U.S. Food and Drug Administration to reduce the risk of heart attack or stroke in people 55 or older who cannot take a class of cardiovascular drugs called ACE inhibitors, maker Boehringer Ingelheim said Monday ... Some studies estimate that as many as 20 percent of people taking ACE inhibitors have side effects, which could prevent the drugs' use as prescribed, the company said. (MEDLINEplus)
Somerset Hospital honored for cardiac lab Oct 13, 2009
Somerset Hospital s Cardiac Catheterization Laboratory has received the American College of Cardiology Foundation s NCDR ACTION Registry GWTG Gold Performance Achievement Award for 2009 one of only 120 hospitals nationwide to do so (Somerset Daily American, PA)
Scientists Jump-start Heart By Gene Transfer Oct 7, 2009
Current treatments usually involve three to four medicines: ACE inhibitors, diuretics, digoxin, and beta blockers. Current clinical agents and treatments focus on the amount of calcium available for contraction, which can provide short-term cardiac benefits, but are associated with an increased mortality in the long-term. (Science Daily)
New Heart Drug Could Be a Lifesaver Aug 31, 2009
I think I speak for every single patient in the universe taking warfarin, beta-blockers, and/or ACE inhibitors, myself included, when I invite debinok1 to stick his or her tongue directly into a 220V wall socket and enjoy that "natural part of the process" they so ardently espouse ... by pub17 August 30, 2009 10:11 PM EDT I think I speak for every single patient in the universe taking warfarin, beta-blockers, and/or ACE inhibitors, myself included, when I invite debinok1 to stick his or her... (CBS News)
Rigels R788 CV adverse event profile draws comparisons to Mercks withdrawn Vioxx, experts say Aug 30, 2009
Anti-diuretics and ACE inhibitors could be used to manage the hypertension, he added ... Patients who developed high blood pressure were treated with ACE inhibitors, which were able to control this adverse event, he added. (FT.com -- Markets)
Mutation in renin gene linked to inherited kidney disease Aug 19, 2009
Because of the significant role renin plays, an entire class of medications used to treat high blood pressure, called ACE inhibitors, are dedicated to preventing blood pressure from rising by blocking the renin from activating angiotensin. A genetic mutation in the gene that encodes renin was first identified as the cause of an hereditary kidney disease by a research group led by Stanislav Kmoch, Ph. (EurekAlert!)
Older drivers unaware of risks from medications and driving Aug 12, 2009
Only 18 percent reported receiving a warning from a health-care professional about potential driver-impairing (PDI) medications such as ACE inhibitors, sedatives and beta-blockers. The study found that such warnings do not increase with increasing numbers of medications used or increasing numbers of medical conditions. (EurekAlert!)
Large Majority of Drivers 55 and Older Unaware of Potentially Dangerous Combination of Medications and Driving, Says New AAA Foundation Study Aug 11, 2009
g., ACE inhibitors, sedatives, and beta blockers) from a healthcare professional. Further, the study found that such warnings do not increase with increasing numbers of medications or with increasing numbers of medical conditions. (PR Newswire)
Fish Oils May Prevent and Treat Heart Disease Aug 7, 2009
But it was a relatively small (4,000 people), short (one-year) trial, and the patients in the trial were already getting intensive drug therapy including clot-busting clopidogrel, cholesterol-lowering statins, beta blockers and ACE inhibitors, Lavie noted. Set against that one trial are the many larger studies cited by Lavie, and epidemiological evidence showing that populations such as Asians and Alaskan Eskimos, whose diets are rich in fish oil, have a low incidence of cardiovascular disease. (MEDLINEplus)
Heart Disease Patients With Previous Blockages More Likely To Die Aug 6, 2009
However, some of the therapies, such as aspirin, are easier and cheaper to administer with very few contraindications and side effects compared to other treatments such as cholesterol-lowering therapy and ACE inhibitors ... 23, 2007) The blood pressure-lowering drugs called ACE inhibitors provide almost ten percent greater protection against coronary heart disease, compared with angiotensin receptor blockers, says new research. (Science Daily)
R788 in TASKi3 Clinical Trial Does Not Meet Efficacy Endpoints in RA Patients Who Had Previously Failed Biologic Therapies - Results Incongruent Jul 24, 2009
The blood pressure medications were standard doses of common blood pressure medications such as ACE inhibitors or diuretics. "For this patient population, patients who failed biologic therapies, their bones and joints appear to respond to R788, but the objective and subjective components of the ACR and DAS28 scores are incongruent, mainly because the reported subjective placebo response rates were higher than expected," said Elliott Grossbard, M.D., chief medical officer for Rigel. (PR Newswire)
Blood Pressure Drugs May Fight Dementia Jul 24, 2009
A team from Wake Forest University studied centrally acting ACE inhibitors and found that they may reduce inflammation that could be part of Alzheimer's disease, a news release said ... Many of the estimated one in three U.S. adults who have hypertension are treated with ACE inhibitors, a class of drugs that help lower blood pressure by causing the blood vessels to relax and widen ... People who were exposed to ACE inhibitors that cross the blood-brain barrier saw an average 65 percent less... (Click2Houston, TX)
The best treatment might be wrong for you Jul 23, 2009
If you're pregnant: Avoid ACE inhibitors and ARBs; they can cause birth defects. Better choices: beta-blockers and vasodilators that relax blood vessels. (MSNBC -- Health)
Some blood pressure drugs may help protect against dementia, study shows Jul 23, 2009
Research suggests that some of the drugs classified as angiotensin-converting enzyme (ACE) inhibitors, specifically those types of ACE inhibitors that affect the brain by crossing the blood-brain barrier, may reduce inflammation that could contribute to the development of Alzheimer's disease, a major cause of dementia ... Many of the estimated one in three U.S. adults who have hypertension are treated with ACE inhibitors, a class of drugs that help lower blood pressure by causing the blood... (EurekAlert!)
FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent Jul 21, 2009
It is not known whether additive effects are present when TEKTURNA or TEKTURNA HCT are used in combination with types of medications called ACE inhibitors or beta-blockers. TEKTURNA HCT can be used first if your doctor thinks you are unlikely to achieve your goal blood pressure with a single medicine. (PR Newswire)
Will Blue Dogs contain health care tab? Jul 15, 2009
Will Blue Dogs contain health care tab. Thinking Right with Jim Wooten. (Atlanta Journal-Constitution -- Opinion)
ACE inhibitors may cause chronic cough Jul 10, 2009
8:44 am July 9, 2009, by jgreene. Q: I started taking lisinopril for high blood pressure. (Atlanta Journal-Constitution -- Health)
Summary for Patients Jul 7, 2009
5926 adults with cardiovascular disease or diabetes who did not have macroalbuminuria or heart failure and had tried ACE inhibitors but could not tolerate them because of side effects ... Only patients who could not tolerate ACE inhibitors were included. (Annals of Internal Medicine)
PI Can Help Lawyers Locate Plaintiffs at Lower Cost Jun 27, 2009
His experience in medical tort-liability case acquisition includes Duragesic Pain Patch, Digitek, Chantix, Asbestosis, Mesothelioma and Silicosis; Vioxx / Celebrex / Bextra; Fen Phen / PPH; Zyprexa / Seroquel ; ACE Inhibitors; Baycol / Rhabdomyolysis; and Paxil / Zoloft. Medical malpractice and product liability experience includes ATV rollover, contact lens solution, defribulator and hernia patch cases. (Yahoo News -- Press Releases)
Mystery cough? 8 possible culprits Jun 23, 2009
ACE inhibitors are a type of medication used to treat high blood pressure and heart failure. About 42 million prescriptions for ACE inhibitors are written each year, and about 1 in 5 people who take the drugs develop a dry cough ... You should never stop taking a prescribed medication without consulting with your doctor, and ACE inhibitors are important medications for lowering blood pressure (a more serious condition than a cough. (CNN -- Law)
Got a mystery cough? 8 possible culprits Jun 20, 2009
ACE inhibitors are a type of medication used to treat high blood pressure and heart failure. (Check out this list of common brand-name and generic drugs that are ACE inhibitors ... About 42 million prescriptions for ACE inhibitors are written each year, and about 1 in 5 people who take the drugs develop a dry cough. (CNN -- Health)
INSPRA approved as adjunct to standard therapy to reduce risk of death following a heart attack Jun 3, 2009
" Congestive Heart Failure; An Unmet Medical Need In Canada, congestive heart failure (CHF) is a major public health problem that currently affects more than 500,000 Canadians;(2) over five years, 45 per cent of people diagnosed with the condition may die.(3) CHF is associated with significant morbidity, mortality and healthcare costs. Much attention has been focused on care for the chronic phase of congestive heart failure, yet a substantial proportion of new cases occur at the time of acute... (Canada Newswire)
Liver disease 'shrunk' by blood-pressure drug Jun 1, 2009
Professor Mann said: "By measuring the amount of active NF-kB in the liver from a biopsy sample, we may be able to tell which patients will benefit from treatment with losartan or similar drugs such as ACE inhibitors. This may prove to be a new treatment for up to half of all liver patients.". . (EurekAlert!)
Queen's hospital wins cardiac care recognition May 28, 2009
Under the GWTGCAD program, patients are started on aggressive risk reduction therapies such as cholesterol-lowering drugs, aspirin, ACE inhibitors and beta-blockers in the hospital and receive smoking cessation/weight management counseling as well as referrals for cardiac rehabilitation before they are discharged, the hospital sid. Hospitals that receive the GWTG-CAD Gold Performance Achievement Award have demonstrated for 24 consecutive months that at least 85 percent of its eligible coronary... (Honolulu Advertiser)
Blood Pressure Meds Broad Impact Examined May 21, 2009
There are five main classes of drugs to lower blood pressure, including diuretics, ACE inhibitors and calcium channel blockers. Researchers said all classes reduced heart risk, and a combination of pills was often the most effective. (KERO 23, CA)
Common Virus May Cause High Blood Pressure May 16, 2009
Doctors typically use generic drugs such as beta blockers and ACE inhibitors to control blood pressure, a condition that affects one in every three adults in the United States. The study suggests that vaccines and antiviral drugs may offer a new approach at treating hypertension, Crumpacker said. (Newsmax)
Water Pills Match Blood-Pressure Drugs May 15, 2009
They were compared to ACE inhibitors, calcium channel blockers and alpha blockers. Water pills, which have been in use for several decades, are usually less expensive than other treatments. (KIRO TV, WA)
Milestone Study On Blood Pressure Medications Confirmed May 15, 2009
ScienceDaily (May 14, 2009) New research supports the findings of a landmark drug comparison study published in 2002 in which a diuretic drug or water pill outperformed other medications for high blood pressure. A scientific team including investigators from The University of Texas Health Science Center at Houston reports the findings in the May 11 issue of the Archives of Internal Medicine. (Science Daily)
Study in Nature Medicine establishes major new treatment target in diseased arteries May 11, 2009
"Currently available and experimental therapies, including ACE inhibitors and antagonists of the angiotensin receptors, MCP-1 and MMPs have significant limits in terms of efficacy in AAA, and thus, CypA inhibitors have the potential to meet significant unmet need," Berk said. "Additionally, inhibition of CypA looks to have tremendous benefit in several diseases that involve blood vessels in the brain and heart. Furthermore, while drugs that inhibit CypA may overlap somewhat with other drugs... (EurekAlert!)
All Blood Pressure Drugs Lower Risk of Heart Attack and Stroke May 9, 2009
Among all the drugs, ACE inhibitors were slightly better, however, the difference was not statistically significant. These findings confirm other research that has shown that ARBs may not be as effective at preventing heart attack as other blood pressure drugs, and that ACE inhibitors are especially effective at preventing heart disease. (MEDLINEplus)
New Target For Maintaining Healthy Blood Pressure Discovered Apr 29, 2009
For instance, ACE inhibitors such as captopril (Capoten) target the formation of angiotensin II, while aliskiren (Tekturna) targets renin. The team assessed the impact of the PGF2 receptor mutations on both blood pressure and RAAS activity. (Science Daily)
Blood Pressure Drug May Not Ease Irregular Heartbeat Apr 17, 2009
The drug does have its uses in helping to control high blood pressure and "in patients who have heart failure, where it is an established therapy where ACE inhibitors are not indicated," Gillis said. But as it now stands "there is no evidence that valsartan is effective as a secondary prevention strategy" for atrial fibrillation, she said. (MEDLINEplus)
Screening may not lower diabetics heart risks Apr 15, 2009
Wackers said people in both groups got significantly more preventive medications over the course of the study, including aspirin, statins and angiotension-converting enzyme or ACE inhibitors, which treat high blood pressure. "Rather than considering this as a negative study, I think there is a positive side to this," Wackers told the briefing. (MSNBC -- Health)
Exercise safe for heart failure patients Apr 8, 2009
All received the usual care, which included drugs such as ACE inhibitors and beta-blockers, and half also did an exercise training program. Exercisers started with a goal of three, 30-minute sessions a week on a stationary bicycle or treadmill. (India Times, India)
Passover's matzoh ball soup may be good for your health Apr 3, 2009
D., and colleagues cite previous studies indicating that chicken breast contains collagen proteins with effects similar to ACE inhibitors, mainstay medications for treating high blood pressure. But chicken breast contains such small amounts of the proteins that it could not be used to develop food and medical products for high blood pressure. (EurekAlert!)
Omega-3s of No Added Benefit to Heart Attack Patients Apr 1, 2009
Almost 94 percent of the patients were prescribed beta-blockers, 83 percent got ACE inhibitors, 95 percent took aspirin, 94 percent got a statin, and 88 percent received the anti-clotting drug clopidogrel (best known as Plavix), according to the report. Over a little more than a year, 4. (MEDLINEplus)
'Miracle heart pill would work' Apr 1, 2009
Single therapies - beta-blockers alone or ACE inhibitors alone - conferred the least benefit, cutting death risk by only about 20. Primary prevention. (BBC News -- Health)
Medics 'can mend a broken heart' Mar 28, 2009
Overall, the majority of those in the registry were prescribed aspirin or heart drugs such as, beta blockers, ACE inhibitors and statins while in hospital. Even though a fifth were were critically ill and required emergency treatment to keep them alive, all the patients survived the first 48 hours and experienced a full recovery. (BBC News -- Health)
Newsweek: Should you have bypass surgery? Mar 17, 2009
First he tried the noninvasive approach: eating better, exercising more and taking the standard medications (aspirin, ACE inhibitors and beta blockers). But even as his condition improved, his peace of mind continued to deteriorate. (MSNBC -- Health)
Will gin-soaked raisins lead to a DUI arrest? Mar 17, 2009
Compounds in eggplant may work like certain blood pressure medicines (ACE inhibitors such as lisinopril) and may also help with insulin resistance (Bioresource Technology, May 2008). You will find a number of other nondrug approaches for controlling hypertension along with a discussion of the pros and cons of common medications in our Guide to Blood Pressure Treatment. (Athens Banner-Herald)
Canine Lyme Disease Nephritis Mar 7, 2009
ACE inhibitors, such as enalapril or benazapril. gastrotomy or PEG tube to provide nutrition if not eating. (Suite101.com)
Sophisticated Molecule Plays Role In Fertility, Blood Pressure, Digestion, Mental Health Feb 27, 2009
23, 2007) The blood pressure-lowering drugs called ACE inhibitors provide almost ten percent greater protection against coronary heart disease, compared with angiotensin receptor blockers, says new research. . (Science Daily)
What is burning mouth syndrome? Can it be treated? Feb 24, 2009
In what are called "secondary" cases, burning mouth is linked to problems such as diabetes, vitamin deficiencies, fungal infections, and medications such as ACE inhibitors, used to treat hypertension, says Dr. Vikki Noonan, an associate professor of oral and maxillofacial pathology at the Boston University School of Dental Medicine. Treating the underlying problem often gets rid of this type of "burning mouth" syndrome. (Boston Globe)
Private firm wins contracts to drive down GPs' drugs spend Feb 21, 2009
5m Schemes likely to focus on statins, preventive inhalers for asthma, ACE inhibitors, PPIs, and antibiotics Savings of 490,000 for PCT but up to 2m saving to be shared between Assura and GP collaborative if saving reaches 10. Readers' comments. (Pulse)
Eggs May Reduce High Blood Pressure Feb 20, 2009
Other research hinted that certain egg proteins might have effects similar to ACE inhibitors, prescription drugs used to treat high blood pressure. Pursuing that lead in laboratory studies, the scientists identified several different peptides in boiled and fried eggs that act as potent ACE inhibitors. (Newsmax)
Exploring Genetic Link Between Migraines, Cardiovascular Trouble Feb 19, 2009
Their theory is bolstered by the fact that both migraines and cardiovascular disease can be treated effectively with ACE inhibitors, drugs that inhibit the angiotensin-converting enzyme, which is critical to cardiovascular health. In the Harvard study, the investigators wanted to see if the ACE D/I gene variant somehow played a role in the heightened risk of stroke and heart attacks among women who have migraines, with or without aura. (MEDLINEplus)
Heart Attack Care: Drugs vs. Stents Feb 19, 2009
All of the patients enrolled in OAT were clinically stable with no chest , and all received appropriate medical treatment with drugs like , beta-blockers, ACE inhibitors, and statins. Quality of Life and Treatment Costs. (WebMD)
Generic Heart Drugs As Good As Brand-Name Counterparts Feb 7, 2009
All of the studies involving beta blockers, antiplatelet agents, statins, ACE inhibitors and alpha-blockers showed clinical equivalence, while 91 percent of randomized controlled trials showed clinical equivalence for diuretics, and 71 percent showed the same for calcium-channel blockers. Yet 53 percent of 43 editorials had a negative take on substituting generic drugs. (MEDLINEplus)
Gender May Influence Heart Failure Treatment Feb 7, 2009
The use of ACE inhibitors and ARBs was lower in female patients treated by male doctors than in male patients treated by either female or male doctors. The dose of ACE inhibitors and ARBs was highest in male patients treated by female doctors and was lower in female patients treated by male doctors. (MEDLINEplus)
Continuous Blood Pressure Monitoring Predicts Risks Feb 7, 2009
Resistant hypertension can be treated successfully with combinations of drugs such as diuretics, ACE inhibitors and calcium channel blockers, he said. Not all doctors are convinced that round-the-clock monitoring is the total solution. (MEDLINEplus)
Viagra May Shield Heart from Blood Pressure Damage Feb 7, 2009
"The evidence is piling up that unbridled Gq signaling is driving a central biological chain reaction in heart failure, and that by extending the protective effects of RGS2 or by developing a test for its presence, researchers can develop new therapies or improve existing ones, including ACE inhibitors and possibly sildenafil, for people with heart failure who will benefit most," Kass said. Doctors currently use so-called ACE inhibitor and ARB inhibitor drugs to block Gq signaling. (MEDLINEplus)
