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A team of doctors tried to save his life by giving him the antiviral drug oseltamivir and washing his kidney, but they had failed, he said. As of Saturday morning, Thailand had confirmed 157 new infection cases, bringing the country's cumulative total to 3,228. (Xinhuanet, China)
Obesity ups swine flu risk Jul 12, 2009
The study, published in advance in the Centers for Disease Control and Prevention's weekly report on death and disease, also suggests doctors can safely double the usual dose of oseltamivir, Roche AG's antiviral drug sold under the Tamiflu brand name. "What this suggests is that there can be severe complications associated with this virus infection, especially in severely obese patients," said CDC virus expert Dr. Tim Uyeki. (India Times, India)
U.S. experts concerned about effectiveness of Tamiflu Jul 9, 2009
"There is certainly a potential for the novel H1N1 viruses to develop resistance to oseltamivir (Tamiflu) and for those resistant viruses to become widespread," he added. "Everyone recognizes that. That is the Achilles' heel of antiviral therapy and it's completely possible that we will see this with the novel H1N1.". (Xinhuanet, China)
WHO: Tamiflu-resistant A/H1N1 flu cases "sporadic" Jul 8, 2009
"Right now these examples of oseltamivir (tamiflu) resistance remain sporadic cases," he told a news briefing in Geneva. Since there is no evidence of widespread cases of anti-virual drugs H1NI virus, "at this point we are not recommending any clinical changes to the approach in treating patients," he said. (Xinhuanet, China)
Why H1N1 Flu Spreads Inefficiently Jul 4, 2009
Moreover, the researchers discovered that the new strain might just need a single change or mutation that could lead to inefficient interaction with the influenza drug oseltamivir, commonly known as Tamiflu, raising the possibility that strains resistant to Tamiflu could emerge easily. The research done at MIT was funded by the Singapore-MIT Alliance for Research and Technology and the National Institutes of General Medical Sciences. (Science Daily)
HK detects A/H1N1 flu virus resistant to Tamiflu Jul 4, 2009
HONG KONG, July 3 (Xinhua) -- A strain of influenza A/H1N1 virus was found resistant to anti-flu drug oseltamivir in Hong Kong laboratory tests, local health authorities said Friday. A spokesman for the Department of Health of Hong Kong said the department's Public Health Laboratory Services Branch (PHLSB) Friday detected a strain of A/H1N1 flu virus which was resistant to oseltamivir, i.e. Tamiflu ... The virus was identified during PHLSB's routine sensitivity test of the new flu virus to... (Xinhuanet, China)
WHO Says Tamiflu-Resistant H1N1 "Isolated Case" Jul 2, 2009
The WHO has previously said that the H1N1 virus is sensitive to a class of antiviral drugs which includes Tamiflu, known generically as oseltamivir, and Relenza by GlaxoSmithKline, known generically as zanamivir. Denmark's State Serum Institute said, when making the announcement on Monday, that it was expected that the strain would at some point show resistance to Tamiflu. (MEDLINEplus)
Scientific System Accurately Predicts Spread Of H1N1 Jul 2, 2009
2, 2009) A mutation of the influenza A (H1N1) virus that is resistant to the drug oseltamivir may pose a serious health threat to hospitalized patients who have a weakened immune system, according to a new. . (Science Daily)
Swine flu 'shows drug resistance' Jun 30, 2009
Routine sampling in the UK has shown that there is currently no resistance to oseltamivir or zanamivir ... Experts have been using tamiflu, also known as oseltamivir, in a bid to stop the H1N1 spreading in communities ... Routine sampling in the UK has shown that there is currently no resistance to oseltamivir or zanamivir. (BBC News -- Asia-Pacific)
Mexico City ready for possible flu spread in winter Jun 27, 2009
The City Health Department has enough anti-viral drugs Oseltamivir to treat 32,000 new A/H1N1 flu cases, Ebrard told reporters during a ceremony where a three-day vacation for health sector workers was announced as rewards for their overload work against the epidemic ... City Health Department Chief Armando Ahued said besides the city-stored Oseltamivir, the Mexican Health Ministry has almost 1 million treatments awaiting needs from Mexico City. (Xinhuanet, China)
Could Older Population Have Enough Exposure To Past H1N1 Flu Strains To Avoid Infection? Jun 26, 2009
(June 18, 2009) With the H1N1 flu outbreak now elevated to pandemic level, scientists reports that oseltamivir (Tamiflu) and zanamivir (Relenza) are relatively safe drugs for use in pregnant and breast-feeding. (June 4, 2009) Scientists around the world are accelerating their efforts to develop a vaccine against the H1N1 influenza virusas rapidly as. (Science Daily)
Vaccinating kids controls swine flu Jun 19, 2009
These measures include the use of antiviral treatments, such as oseltamivir, social distancing (for example, closing schools and stopping public transport) and quarantining infected individuals. Pharmaceutical companies have also stepped up production of vaccines effective against this particular strain of the virus. (India Times, India)
Vast Majority Won’t Have Access To Antivirals In Pandemic, But Generic Drugs Could Help Prevent Deaths Jun 16, 2009
23, 2007) Stockpiling large amounts of oseltamivir (Tamiflu) and related antiviral drugs with the intent to treat a large fraction of the population is a key part of pandemic preparedness of many countries. (Jan. (Science Daily)
Pregnancy increases swine flu risk Jun 16, 2009
With the H1N1 flu outbreak now elevated to pandemic level, the article in CMAJ (Canadian Medical Association Journal) has reported that oseltamivir (Tamiflu) and zanamivir (Relenza) are relatively safe drugs for use in pregnant and breast-feeding women ... For treatment or prevention during the current pandemic, "oseltamivir appears to be the drug of choice because there are more data on its safety in pregnancy," writes Dr. Shinya Ito, Head of the Division of Clinical Pharmacology and Toxicology... (India Times, India)
Thailand confirms fourth case of Influenza A/H1N1 May 31, 2009
Health officials closely watched the patient and gave doses of Oseltamivir to five of his family members for five consecutive days. The patient's saliva samples were examined by the Department of Medical Sciences' National Influenza Center and Siriraj Hospital and both confirmed that the samples contained the A/H1N1 strain, the website of the Bangkok Post reported. (Xinhuanet, China)
Youngest H1N1 patient discharged from east China hospital May 28, 2009
The infant was treated with oseltamivir, one of the most effective drugs used against the A/H1N1 virus, Lin said. The little girl had been treated well, the grandmother told Xinhua. (Xinhuanet, China)
U.S. Officials Consider Bumping Up Flu Shot Season May 22, 2009
Tamiflu, or oseltamivir, is made by Roche AG and Gilead Sciences Inc while the inhaled drug Relenza, or zanamivir, is made by GlaxoSmithKline and Biota Inc.. The new flu seems to be about as contagious as seasonal flu, Jernigan said. (MEDLINEplus)
Value of vaccination in fight against diseases May 20, 2009
These are on top of using Tamiflu (oseltamivir) antivirals to treat those already infected, he said. Antivirals, Reingold added, should also be given to frontline healthcare workers and emergency response personnel as a preventive measure, but not to be administered to the general population. (The Star Online, Malaysia)
Veterinarians At High Risk For Viral, Bacterial Infections From Animals May 19, 2009
10, 2009) Influenza A viruses (H1N1 subtype) that are resistant to the drug oseltamivir circulated widely in the US during the 2007-2008 influenza season, with an even higher prevalence of drug resistance. (Nov. (Science Daily)
H1N1 case confirmed in Hyderabad May 17, 2009 WHO Meets On Swine Flu Vaccine May 15, 2009 CDC: Pregnant women should be wary of swine flu May 13, 2009 Health authorities prepare to limit flu drug use May 13, 2009 Congo-Brazzaville: Boost for Flu Preparedness May 12, 2009 A/H1N1 flu continues to spread in Asia-Pacific as China confirms first case on mainland May 12, 2009 Seven passengers from a flu-infected flight were put under quarantine in China on Saturday, the Chinese Health Ministry said.• China alters treatment plan of A/H1N1 influenza May 10, 2009 Drug Resistance: New Swine Flu Concern May 7, 2009 New swine flu concern going forward: Drug resistance May 6, 2009 Flu fears subside, butnext wave looms May 5, 2009 Swine Flu: A Survivor's Tale May 5, 2009 Ravalli County HEAT Team to discuss swine flu May 5, 2009 Warning About Swine Flu Scams May 4, 2009 Mexican worker watched as flu victim lost her fight for life May 4, 2009 FDA, FTC Warn Public Of Fraudulent 2009 H1N1 Influenza Products May 3, 2009 Mexico Begins Shutting down as Flu Fears Spread May 2, 2009 HIV patients at higher risk from flu, WHO says May 2, 2009 Swine flu cases reach 653 worldwide May 2, 2009 Mexico encouraged by fall in new flu cases May 1, 2009 Using a small stockpile of a secondary antiviral drug in a flu pandemic May 1, 2009 ON BRINK OF PANDEMIC May 1, 2009 Gilead, Roche ready with swine flu treatments May 1, 2009 Who flu hits hardest difficult to assess May 1, 2009 REGION: Officials urge calm, normal precautions Apr 30, 2009 Will swine flu be a boon for Indian generics Apr 30, 2009 Nigeria: Swine Flu - No Reported Case Yet, Says Govt Apr 30, 2009 South Africa: Country Not Ready for Swine Flu Apr 30, 2009 More of this story Apr 29, 2009 Tests rule out swine flu on two suspected cases in South Dakota (4948) Apr 29, 2009 Swine flu cases reported in North Carolina Apr 29, 2009 Swine Flu Outbreak Continues To Grow, As Worldwide Pandemic Alert Level Raised To Phase 4 Apr 29, 2009 Global response Apr 29, 2009 Local officials keep watchful eye on swine flu Apr 29, 2009 The facts: Swine flu Apr 28, 2009 Is Swine Flu Really a Major Danger? Apr 28, 2009 U.S. Declares Public Health Emergency in Response to Swine Flu Apr 28, 2009 WHO Warns of Possible Pandemic as Mexico Seeks to Contain Swine Flu Apr 28, 2009 Roche scales up production of flu cure Apr 28, 2009 Drug and Vaccine Makers on Standby Over Swine Flu Apr 28, 2009 Swine flu threat calls for precaution, preparation Apr 28, 2009 How to protect yourself Apr 28, 2009 DRUG SHORTAGES Apr 28, 2009 Questions and answers about swine flu Apr 28, 2009 South Dakota officials concerned by swine flu1:36 pm | (No comments posted.) Apr 28, 2009 Government moves against swine flu Apr 28, 2009 Latest from the CDC Apr 28, 2009 Containing Swine Flu outbreak not feasible Apr 28, 2009 Swine Flu: Public Health Emergency Declared, Investigation Continues Apr 28, 2009 Swine Flu Could be the News Story of the Decade Apr 28, 2009 Chemical that can stop flu spread found Apr 16, 2009 Compound identified that may fight bird flu Apr 16, 2009 Flu Strikes a Milder Blow This Season Apr 10, 2009 FEATURE-Profit drives drug misuse in Asia Apr 6, 2009 Influenza A Becoming Increasingly Resistant To Drug Oseltamivir Mar 11, 2009 Resistance to flu drug widespread in U.S.: study Mar 4, 2009 Resistance to Tamiflu Growing Mar 4, 2009 Flu virus increases resistance to Tamiflu Mar 3, 2009 Drug-resistant Influenza A Virus Potentially Serious To High-risk Patients Mar 3, 2009 Flu strain proves resistant to medication... Mar 3, 2009 What You Need to Know About Drug-Resistant Flu Feb 24, 2009 * A bird flu epidemic in the making Feb 12, 2009 DPH: Influenza on the rise Feb 7, 2009 Common Flu Strain Resistant to Popular Antiviral Drug Feb 7, 2009
The patient, whose condition is stable, is undergoing treatment in the hospital and is being administered with Oseltamivir, the drug used to cure the infection. Though swine flu is an air-borne disease, it does not spread if the affected are isolated for a period of ten days after contracting the infection, said K Shubhankar, head of the Airport Health Organisation (APHO). (India Times)
Mathematical Model Developed To Predict Immune Response To Influenza May 15, 2009
2, 2009) A mutation of the influenza A (H1N1) virus that is resistant to the drug oseltamivir may pose a serious health threat to hospitalized patients who have a weakened immune system, according to a new ... 10, 2009) Influenza A viruses (H1N1 subtype) that are resistant to the drug oseltamivir circulated widely in the US during the 2007-2008 influenza season, with an even higher prevalence of drug resistance. (Science Daily)
The drug, also known as oseltamivir, is one of two anti-virals shown to work against swine flu. WHO said Cipla's generic version was as effective as the original made by Swiss firm Roche Holding AG and would hopefully make the drug more accessible to poor countries. (Time.com)
Treatments include such drugs as oseltamivir, sold as Tamiflu, and zanamivir, sold as Relenza, she says. "Sometimes physicians are reluctant to treat pregnant women with medicines, and sometimes pregnant women are reluctant to take medicines because, of course, they are sometimes risky during pregnancy,? Schuchat says. But ?the experts who have looked into this situation really strongly say that the benefit of using antiviral drugs to treat influenza in a pregnant women outweigh the theoretical... (USA Today)
Roche said it was ramping up production of the drug, known generically as oseltamivir. Relenza, known generically as zanamivir, is the other drug recommended for use against H1N1 and is made by GlaxoSmithKline under license from Australia's Biota. (The Star Online, Malaysia)
According to the UN World Health Organization (WHO) country representative, Mamadou Ball, the ROC has supplies of the anti-viral Tamiflu (oseltamivir) being used to treat the disease. WHO has also accredited at least 15 African laboratories to carry out flu testing. (allAfrica.com)
Thailand's Health Ministry also said it will propose to the weekly cabinet meeting on Tuesday a plan to purchase materials to additionally produce 2 million pills of the antiviral Oseltamivir, amid the rising A/H1N1 flu outbreak outside the country. In what may be a good sign, the Singaporean health authorities on Monday lowered its alert level for influenza A/H1N1 from "orange," next to the highest "red," to "yellow.". (Xinhuanet, China)
Confirmed carriers will be treated with oseltamivir, an inhibitor that proved effective in initial medical tests in containing the virus, it says. The notice says the authorities will closely monitor the development of virus treatment and revise the plan when it deems "necessary". (Xinhuanet, China)
H1N1 is susceptible to two antivirals, Tamiflu (oseltamivir) and Relenza (zanamivir), which are helpful if taken within several days of having symptoms, the Centers for Disease Control and Prevention says. In the week after the USA had its first cases, new antiviral prescriptions at retail pharmacies were 19 times higher than in the previous week, health care information company SDI said Tuesday. (13WMAZ.com, GA)
H1N1 is susceptible to two antivirals, Tamiflu (oseltamivir) and Relenza (zanamivir), which are helpful if taken within several days of having symptoms, the Centers for Disease Control and Prevention says. U.S.: 1st AMERICAN DEATH: SCIENTISTS: INTERACTIVE MAPS. (USA Today)
Before this new strain of swine flu emerged, the dominant strain of H1N1 influenza was almost entirely resistant to oseltamivir, or Tamiflu. So far, the new strain is susceptible to Tamiflu and to zanamivir, or Relenza. (MSNBC -- Health)
Doctors soon gave Bonilla an anti-viral drug that is known in Mexico as oseltamivir (and more popularly known as Tamiflu) making his condition rapidly improve. In some ways, the timing of sickness was lucky, he says. (Time.com)
The CDC recommends the prescription antiviral drugs oseltamivir or zanamivir to treat and/or prevent swine influenza viruses. A portion of Montana s allotment of antiviral medication and personal protective equipment from the national stockpile - or enough to handle 25,000 victims - is being moved to storage within the state in the next week. (Sioux Falls Tri-State Neighbor, SD)
The two antiviral drugs approved by the FDA for treatment and prophylaxis of the 2009 H1N1 influenza virus are Tamiflu (oseltamivir phosphate) and Relenza (zanamivir). Tamiflu and Relenza, in addition to their approved labeling, have Emergency Use Authorizations that describe specific authorized uses during this public health emergency. (W-USA News, DC)
Although he has not heard the test results, he is being treated with oseltamivir, the generic name for the Tamiflu antivirals that have been deployed against swine flu ... Mr Bonilla improved dramatically when he was given oseltamivir. (Sydney Morning Herald -- World)
The two antiviral drugs approved by the FDA for treatment and prophylaxis of the 2009 H1N1 influenza virus are Tamiflu (oseltamivir phosphate) and Relenza (zanamivir) ... 10, 2009) Influenza A viruses (H1N1 subtype) that are resistant to the drug oseltamivir circulated widely in the US during the 2007-2008 influenza season, with an even higher prevalence of drug resistance ... 2, 2009) A mutation of the influenza A (H1N1) virus that is resistant to the drug oseltamivir may pose a serious health... (Science Daily)
Fukuda said Swiss drugmaker Roche was stepping up production of Tamiflu to deal with the infection at that the WHO had released some of its own stockpiles of the drug -- known generically as oseltamivir and proven effective against the new strain -- to developing countries deemed most at need, including Mexico. The World Bank also announced it was beginning to transfer flu emergency funds to Mexico and Argentina. (MEDLINEplus)
"Patients at higher risk for complications of influenza including those with HIV infection should be among those prioritised for antiviral treatment with oseltamivir or zanamivir which shortens illness duration and severity in seasonal influenza," its guidance read. It is best if people infected with the flu strain start to take the antivirals within 48 hours of the onset of symptoms, according to the WHO. There are no known problems with taking those drugs alongside the anti-retrovirals that... (The Star Online, Malaysia -- News)
Tamiflu (oseltamivir) and Relenza (zanamivir) are successful in helping treat the virus if taken within several days of having symptoms, according to the Centers for Disease Control and Prevention. The drugs can shorten the length of the disease and its severity. (USA Today)
Fri, 1 May 07:48:59 GMT. (For full coverage of the flu outbreak, click [nFLU]). (AlertNet)
Many countries are investing in large stockpiles of a single drug, oseltamivir (Tamiflu) ... Using a mathematical model to represent the global spread of pandemic influenza, an international team of researchers led by Joseph Wu of the University of Hong Kong, and including collaborators in the UK and the US, found that treating as few as only the first 1% of the population in a local epidemic with a secondary drug rather than with oseltamivir, could substantially delay the development of... (EurekAlert!)
Reuters AlertNet - Mexico begins shutting down as flu fears spread. Fri, 1 May 06:02:44 GMT. (AlertNet)
Swine influenza A viruses detected in the United States and Mexico appear resistant to two antiviral drugs amantadine and rimantadine but laboratory tests indicate the viruses are sensitive to Tamiflu, also known as oseltamivir, and Relenza, which is known as zanamivir. The Tamiflu oral antiviral, approved in the U.S. to treat and prevent influenza A and B virus infection in people age one or older, is sold by Ltd., which pays sales-related royalties to Gilead. (East Bay Business Times, CA)
inhibitors - Tamiflu (oseltamivir phosphate) and Relenza (zanamivir). stop budding process. (Globe and Mail -- National)
Tamiflu is the brand name of the drug Oseltamivir, and Relenza the brand name of Zanamivir. The two are among four influenza antiviral drugs approved for use in the United States, according to the CDC. The other two drugs do not work against swine influenza viruses. (North County Times)
Indian generic drug makers Cipla Ltd. and Ranbaxy Laboratories Ltd. said this week that they could ramp up production of Oseltamivir, the generic version of Tamiflu, if needed ... 5 million doses of Oseltamivir in the next month or so ... Ranbaxy officials said late Tuesday that the company can make Oseltamivir ``at fairly short notice,'' but declined to detail production capacity. (India Times)
Ojuolape further stressed that appropriate drugs and supplies such as Oseltamivir, PPEs, disinfectants, face masks and transport media (VTM) have been distributed to all states of the federation and Abuja, while states' health authorities had been advised and strongly encouraged to acquire more in order to beef up and strengthen their level of preparedness. "The Federal Ministry of Health recommends routine precautions to prevent the spread of infectious diseases such as washing your hands... (allAfrica.com)
In the absence of a vaccine for swine flu, antiviral medicines such as oseltamivir (Tamiflu) and zanamivir (Relenza) have been used to treat the disease. Dr Lucille Blumberg, of the South African National Institute for Communicable Diseases, confirmed on 29 April that two suspected cases of swine flu were being investigated. (allAfrica.com)
The virus is reportedly susceptible to four prescription anti-viral drugs: Amantadine, Rimantadine, Oseltamivir and Zanamivir. CDC acting head Richard Besser reiterated the Obama administration s call for calm and taking precautions against the swine flu (H1N1), which the CDC reports has affected people in California, Kansas, New York, Ohio and Texas. (Westerly Sun, RI)
Two antiviral medications have been shown effective in the treatment and prevention of the swine flu: oseltamivir and zanamivir. Hollingsworth said the state has stockpiled 80,000 doses of the antiviral drugs, and there are an additional 114,000 doses in a federal stockpile for South Dakota. (Rapid City Journal, SD)
Swine flu is treated with the antiviral drugs oseltamivir or zanamivir. Delivery is expected within a week. (Roanoke Rapids Daily Herald, NC)
The swine influenza A (H1N1) virus is susceptible to the prescription antiviral drugs oseltamivir and zanamivir. This is a rapidly evolving situation and CDC will provide updated guidance and new information as it becomes available. (Science Daily)
The country is able to provide 3,000 treatments with Oseltamivir to 1,500 adults and the same number of children. Health ministers from Guatemala, Nicaragua, Panama and Dominican Republic will seek to create a "sanitary cordon" in the region. (BBC News -- Asia-Pacific)
Prescription antiviral medications that can treat or prevent the swine flu are oseltamivir or zanamivir in pill, liquid or inhaler. The medicine keeps flu viruses from reproducing in a person's body, can make the illness milder in people who get the flu and prevent serious flu complications, according to the CDC.. (Keokuk Daily Gate City, IO)
The US Centres for Disease Control and Prevention (CDC) recommends oseltamivir (marketed as Tamiflu) and zanamivir (marketed as Relenza) for treating or preventing infection. These drugs work by preventing the virus from reproducing. (iAfrica.com)
Oseltamivir (Tamiflu) and zanamivir (Relenza) still work, though they need to be taken early in the course of the illness. Thorough hand washing is extremely effective in prevention the spread of the common cold. (Suite101.com)
The viruses found in the United States are resistant to two antiviral medications -- amantadine and rimantadine -- but are susceptible to the antivirals oseltamivir (Tamiflu) and zanamivir (Relenza), Schuchat said. Schuchat said steps were already being taken to devise a vaccine against this strain of swine flu, although the process takes time. (MEDLINEplus)
The viruses found in the United States are resistant to two antiviral medications -- amantadine and rimantadine -- but are susceptible to the antivirals oseltamivir (Tamiflu) and zanamivir (Relenza), Schuchat said. Swine flu is a respiratory disease of pigs caused by type A influenza. (MEDLINEplus)
Tamiflu, or oseltamivir, is given as a convenient tablet, and was originally invented by US biotech company Gilead Sciences Inc. Reuters. Most Viewed. (The Star Online, Malaysia -- Business)
Roche Holding AG's Tamiflu, known generically as oseltamivir, and GlaxoSmithKline Plc's Relenza, or zanamivir, are both recommended drugs for seasonal flu and have been shown to work against viral samples of the new disease. Tamiflu is expected to be in greatest demand should swine flu develop into a pandemic, as experts fear it may, since it is given as a tablet. (MEDLINEplus)
Although there are no antiviral drugs that can prevent the illness, the new strain of swine influenza virus is susceptible to the antiviral medications zanamivir (Relenza) and oseltamivir (Tamiflu). It is resistant to the antiviral medications amantadine and rimantadine, though. (USA Today -- Money)
"However, we do have anti-virals that work against this swine flu," said Skinner, referring to oseltamivir (Tamiflu) and zanamivir (Relenza). "Someone who has [swine flu], if they are treated early, the anti-flu medicines work against this.". (CNN -- Health)
Mon, 19:15 27 Apr 2009 GMT. Global antiviral supply to be strained in pandemic. (AlertNet)
A: There are four different antiviral drugs that are licensed for use in the U.S. for the treatment of influenza: amantadine, rimantadine, oseltamivir and zanamivir ... At this time, CDC recommends the use of oseltamivir or zanamivir for the treatment and/or prevention of infection with swine influenza viruses. (Honolulu Advertiser)
Federal health officials are recommending the use of oseltamivir or zanamivir for the treatment of infection with swine influenza viruses. They said the H1N1 viruses are resistant to amantadine and rimantadine. (Watertown Public Opinion, SD)
Drugs for treatment: The Centers for Disease Control and Prevention recommends the use of two antiviral drugs, oseltamivir or zanamivir, to treat or prevent infection. No vaccine: There is no vaccine currently available. (Florida Today)
Laboratory testing has found the swine influenza A (H1N1) virus susceptible to the prescription oseltamivir and zanamivir. This is a rapidly evolving situation and CDC will provide updated guidance and new information as it becomes available. (Florida Today)
CDC recommends the use of oseltamivir or zanamivir for the treatment and/or prevention of infection with these swine influenza viruses. Antiviral drugs are prescription medicines (pills, liquid or an inhaler) that fight against the flu by keeping flu viruses from reproducing in your body. (Dayton Business Journal, OH)
Laboratory testing has found the swine influenza A (H1N1) virus susceptible to the prescription antiviral drugs oseltamivir and zanamivir. This is a rapidly evolving situation and CDC will provide updated guidance and new information as it becomes available. (Science Daily)
There are four different antiviral drugs that are licensed for use in the US for the treatment of influenza: amantadine, rimantadine, oseltamivir and zanamivir ... At this time, CDC recommends the use of oseltamivir or zanamivir for the treatment and/or prevention of infection with swine influenza viruses. (Alva Review Courier, OK)
The search for such new inhibitors has grown more urgent in recent years as drugs, like oseltamivir, have become largely ineffective against certain flu strains, like the H1N1 seasonal flu virus. Experts now question how well the drug would stand up against H5N1, should it unleash a pandemic. (India Times, India -- Health/Science)
The search for such new "inhibitors" has grown more urgent in recent years as drugs, like oseltamivir, have become largely ineffective against certain flu strains, like the H1N1 seasonal flu virus ... "We have found a compound that is different from oseltamivir but which acts in the same way," said Leo Poon, a microbiologist at the University of Hong Kong ... "An analogy would be like we have a door with a keyhole, but the hole has changed, and the key, in this case oseltamivir, can't lock the... (MSNBC -- Health)
The drug Tamiflu (oseltamivir), routinely prescribed to people with the flu, is resistant to this year's H1N1 strain, and the H3N2 flu strain is resistant to two other antivirals, rimantadine (Flumadine) and amantadine (Symmetrel). Although 146 million doses of flu vaccine were distributed this season, the number of people who were actually vaccinated is unknown, Fry said. (MEDLINEplus)
The most recent example of growing resistance involves the drug oseltamivir, which researchers in the United States found was now ineffective against 98 percent of the H1N1 seasonal human influenza virus strains. Oseltamivir is known by the brand Tamiflu and manufactured by Roche AG
10, 2009) Influenza A viruses (H1N1 subtype) that are resistant to the drug oseltamivir circulated widely in the U.S. during the 2007-2008 influenza season, with an even higher prevalence of drug resistance during the current 2008-2009 influenza season, according to a new study ... During the 2007-2008 influenza season, increased levels of resistance to the influenza drug oseltamivir (marketed as Tamiflu) were detected for the first time in the United States and worldwide ... In addition, early... (Science Daily)
But the news is sobering because the pill, known generically as oseltamivir, is one of the few weapons against influenza, which kills an estimated 36,000 people in the United States in an average year ... "As of February 19, 2009, resistance to oseltamivir had been identified among 264 of 268 (98.5 percent) U.S. influenza A(H1N1) viruses tested," the researchers wrote in the Journal of the American Medical Association. (Yahoo News -- Top Stories)
But, always, Fry emphasized, "Our message is to get vaccinated with the influenza vaccine. The current influenza vaccine has three different virus types in it, and the H1 strain that is in the vaccine is the same strain that is resistant to oseltamivir [Tamiflu], so the best prevention is still getting the vaccine.". "We're fortunate in that this is a very mild flu season, and we're not seeing either the numbers of cases or the complications that we normally see in a bad flu season," said Dr.... (MEDLINEplus)
Some 264 of 268 samples of the H1N1 strain taken this flu season were resistant to Tamiflu, also known as oseltamivir, the agency said today in a study in the Journal of the American Medical Association. The oral antiviral capsule is sold by Ltd.. (Dayton Business Journal, OH)
2, 2009) A mutation of the influenza A(H1N1) virus that is resistant to the drug oseltamivir may pose a serious health threat to hospitalized patients who have a weakened immune system, according to a new study ... A global emergence and rapid spread of oseltamivir-resistant influenza A(H1N1) viruses carrying a neuraminidase (NA; an enzyme) gene H274Y mutation has been observed since January 2008 ... "However, current widespread circulation of oseltamivir-resistant influenza A(H1N1) viruses... (Science Daily)
A report in the Journal of the American Medical Association (JAMA) found that the H1N1 subtype of influenza A viruses commonly proved resistant to the popular drug oseltamivir. Oseltamivir, sold commercially in the United States as the drug Tamiflu, is produced by Swiss pharmaceutical giant Roche, and is the main antiviral remedy on the market ... Data last year for 99 individuals infected with oseltamivir-resistant influenza found that five of the patients had to be hospitalized, four of whom... (The Drudge Report)
The Centers for Disease Control and Prevention (CDC) reported in the fall that the most common strain of flu now making the rounds in the U.S. is resistant to oseltamivir, or Tamiflu, the most popular antimicrobial used to treat influenza. But that doesn't mean a pandemic is necessarily on the way. (Time.com)
Research published in the New England Journal of Medicine shows that during the past two years, resistance of H1N1 and H5N1 to the drug Oseltamivir X marketed as Tamiflu X has increased sharply, indicating that the H5N1 bird flu virus has mutated and adapted. These scientific data suggest that a nightmare X the outbreak of a new flu strain among humans X will soon be upon us. (Taipei Times, Taiwan -- World Business)
The CDC recently announced that the predominant strain of influenza circulating nationally (influenza A H1N1) has developed resistance to a widely used antiviral medication, oseltamivir (Tamiflu). Doctors often prescribe antiviral medications to treat the symptoms of people with the flu. (Lincoln Journal, MA)
While the cause of the mutation that made the virus resistant to Tamiflu (oseltamivir) isn't known, experts suspect it was caused by the wide use of Tamiflu in other countries to treat upper respiratory infections. There were reports last year from Europe and other countries that a certain type of flu -- H1N1 -- was resistant to oseltamivir, according to Dr. Joseph Bresee, chief of flu prevention at the U.S. Centers for Disease Control and Prevention ... "What happens frequently is that one type... (MEDLINEplus)
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