You Just Move Like A Mouse, Or Do So Abnormally Like A Mutant Mouse May 2, 2008
This discovery is not only expected to help in the practical diagnosis and evaluation of depressive disorder, but even in the development of a new drug targeting the "depression genome". The observation that healthy mice show behaviour statistics during rest and activity indistinguishable from humans may have a fundamental impact on the understanding of the higher brain functions. (Science Daily)
Researchers Mimic Bacteria To Produce Magnetic Nanoparticles Apr 16, 2008
Using that principle, a diverse, interdisciplinary group of researchers at the U.S. Department of Energy s Ames Laboratory is mimicking bacteria to synthesize magnetic nanoparticles that could be used for drug targeting and delivery, in magnetic inks and high-density memory devices, or as magnetic seals in motors. See also. (Science Daily)
Researchers at Hormel Institute in Austin focusing on protein with possible cancer tie-in Mar 7, 2008
Once you identify this target, the next step is developing a drug targeting it. We are getting close. (Austin Daily Herald, MN)
Key Interaction In Cholesterol Regulation Discovered Feb 7, 2008
While statin drugs work by increasing the number of LDL receptors on cells, a drug targeting PCSK9 might prevent the existing receptors from being degraded. "These studies suggest that inhibiting PCSK9's action may be another route to lowering LDL cholesterol in individuals with high cholesterol," said Dr. Horton. (Science Daily)
Growth Factor Receptor Affects Prostate Cancer Progression Jan 3, 2008
2, 2008) Breeding mice with a gene for a cellular receptor that can be turned on and off-at will-not only enabled researchers at Baylor College of Medicine in Houston to show how prostate cancer progresses, but also provides a model for studying when a drug targeting a gene will have an effect on the cancer. See also. (Science Daily)
Biogen Idec sale books not out yet, but first round bids expected early November, people familiar say Oct 27, 2007
The first person familiar noted that decisions pertaining to Tysabri and Rituxan, a drug targeting Non-Hodgkins Lymphoma which Biogen has a collaborative agreement with Genentech to market, would be crucial to determining the fate of buyers. Those two products are quite key and I think it would be very difficult to do a deal without, this person said. (FT.com -- Markets)
Unhappy past? Forget about it Jul 13, 2007
A drug targeting specific brain regions might eventually boost the ability to suppress, said John Gabrieli at the Massachusetts Institute of Technology. For a mother haunted by the memory of her sons suicide, he said, it is hard to imagine that youd ever get her to forget that the event occurred. (MSNBC -- Health)
Improving Colorectal Cancer Treatment Jun 29, 2007
Pending questions include how this protein is expressed in normal and cancer cells, how it helps cancer cells escape ionizing radiation and chemotherapy, and which patients will benefit from treatment with a drug targeting clusterin. Claus Lindbjerg Andersen, Torben Falck Orntoft, and colleagues discovered that clusterin is not expressed in normal cells, while in 25 percent of colorectal tumors, the cancer cells contained clusterin. (Science Daily)
SERIES: The Last, Best Hope May 3, 2007
Leia is the first St. Jude patient enrolled in a national study of a new drug targeting the tumor. Along with removing the tumor, Leia's St. Jude doctors are eager for evidence of how it might be working. (The Commercial Appeal, TN)
Raptor Pharmaceuticals Corp. Announces Fiscal 2007 Second Quarter Results, Updates Programs and Appoints Investor Relations Firm Apr 16, 2007
In addition, the Company has recently submitted two new provisional patent applications in the U.S. One covers a new family of RAP peptides that have potential applications as therapeutics and as drug targeting agents and the second application further supports and expands the Company's coverage in specific disease indications. Also, to accommodate near-term personnel and laboratory expansion, the Company has leased an additional 2,500 s.f. contiguous to its present location at 9 Commercial... (Canada Newswire)
Homing pigeons get their bearings from their beaks Mar 17, 2007
The minute iron oxide crystals have also interested nanotechnologists concerning their potential application for accurate drug targeting and data storage. Post this story to. (Telegraph.co.uk)
Simulating New Therapies for Metabolic Diseases Jan 31, 2007
VIRTUAL DRUG TARGETING: A new simulation of the human metabolism could lead to better therapies for high cholesterol and diabetes. Sure, it is just on a computer but a new reconstruction of human metabolic activity, created by researchers at the University of California, San Diego, could revolutionize the study of how the body breaks down food into energy and assembles hormones and proteins to power biological processes crucial to daily life. (Scientific American)
Washington U. signs licensing deal with Raptor Nov 7, 2006
"Mesd significantly adds to our growing franchise in the drug targeting area," Dr. Christopher Starr, 's CEO, said in a statement. "Mesd complements and extends our current programs and we believe will increase our reach and capabilities into a number of under-served disease indications with substantial market potential.". (St. Louis Business Journal, MO)
Raptor Pharmaceuticals Corp. Announces an Exclusive Worldwide License Agreement for Mesd Reagents for Treatment of Cancer and Osteoporosis Nov 6, 2006
QUICK SEARCH BY ORGANIZATION. FREE SUBSCRIPTION SERVICES. (Canada Newswire)
ChemGenex to trial leukaemia drug Jun 13, 2006
ChemGenex said Novartis had a drug targeting patients with resistance to Gleevec but it was in the pre-clinical phase and only likely to go into Phase 1 trials in 2007. Sales of Gleevec for CML patients amounted to $US630 million in 2004. (Sydney Morning Herald -- Business)
Osiris files for IPO May 13, 2006
In addition to the GvHD clinical trial, Osiris has trials underway for a drug targeting Crohn's Disease. The company also has an ongoing clinical trial with a drug that attempts to regenerate cartilage in the knee and another drug designed to repair damaged heart tissue in heart attack patients. (Baltimore Business Journal, MD)
Studies Suggest New Targets For Tuberculosis Treatments Mar 8, 2006
So any drug targeting the TB proteasome would have to be extremely specific. This was one reason for conducting such detailed structural and biochemical studies, to try to identify the unique characteristics that would allow such a targeted drug design. (Science Daily)
