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    News and Articles on Double Blind Study

    Archives: Double Blind Study

    An effective probiotic that can fight Listeria monocytogenes bacteria  Aug 29, 2008
    According to Mr. Claude Chevalier, the company's President and CEO : "it goes without saying that this study constitutes a significant indicator of Bio-K+CL1285(R)'s ability to act on pathogenic bacteria. Although further study is required to understand the full extent of the product's effectiveness in the human body, we think it is crucial that Canadians be aware right now of the results obtained in vitro, because they demonstrate that the product reduces the growth of the pathogenic bacterium,... (Canada Newswire)

    Ginseng Cold Medicine Safe for Kids  Aug 19, 2008
    Results of the double-blind study were published in Pediatrics, the journal of the American Academy of Pediatrics. COLD-fX is a patented extract of North American ginseng, and its the most popular adult cold and flu remedy in Canada. (Newsmax)

    New drug targets main culprit in common colds  Aug 12, 2008
    This double-blind study will be carried out in a controlled quarantine facility and will check the viral count and cold symptom improvement. The full results expected by the end of April 2009, will then be used to help select doses for treatment and prevention of HRV infection in later clinical studies. (News-Medical.net)

    Estrogen Relieves Psychotic Symptoms In Women With Schizophrenia  Aug 6, 2008
    D., of The Alfred and Monash University and The Alfred Hospital, Melbourne, Australia, and colleagues conducted a randomized, double-blind study involving 102 women of child-bearing age with schizophrenia. For 28 days, 56 women were randomly assigned to receive 100 micrograms of estradiol daily via a skin patch and 46 women received a placebo skin patch in addition to their regular medications. (Science Daily)

    Psychotic Symptoms Relieved With Estrogen Treatment  Aug 5, 2008
    " Estradiol is the member of the estrogen family best represented in the human body. While it is usually associated with female secondary sex characteristics, both males and females maintain levels of estradiol. To explore this association, Jayashri Kulkarni, M.B.B.S., M.P.M., F.R.A.N.Z.C.P., Ph.D., of The Alfred and Monash University and The Alfred Hospital, Melbourne, Australia, and colleagues performed a randomized, double blind study in women of child-bearing age with schizophrenia. A total... (Medical News Today)

    BioMS Medical completes patient recruitment in phase III U.S. multiple sclerosis trial  Aug 1, 2008
    QUICK SEARCH BY ORGANIZATION. FREE SUBSCRIPTION SERVICES. (Canada Newswire)

    First Patients Implanted In Study Evaluating Deep Brain Stimulation For Depression  Jun 30, 2008
    We are excited to be part of the first double-blind study of Deep Brain Stimulation for depression and remain hopeful that this therapy may prove beneficial for this seriously ill patient population, said Anthony D'Agostino, M.D., medical director of Alexian Brothers Behavioral Health Hospital and the principal investigator at the study site. The study is an important contribution to the advancement of treatment options for severely depressed patients. (Science Daily)

    Rivaroxaban after Total Hip Arthroplasty  Jun 26, 2008
    Methods In this randomized, double-blind study, we assigned 4541 patients to receive either 10 mg of oral rivaroxaban once daily, beginning after surgery, or 40 mg of enoxaparin subcutaneously once daily, beginning the evening before surgery, plus a placebo tablet or injection. The primary efficacy outcome was the composite of deep-vein thrombosis (either symptomatic or detected by bilateral venography if the patient was asymptomatic), nonfatal pulmonary embolism, or death from any cause at 36... (New England Journal of Medicine)

    A Healthy Mind Can Help Fight HIV  Jun 24, 2008
    According to Leserman, researchers could definitively link mental issues to physical health by launching what's known as the "gold standard" of research -- a randomized, double-blind study. Hypothetically, researchers could track two randomly chosen groups of HIV patients, some whom are depressed and stressed and others who aren't. (MEDLINEplus)

    30 percent RA patients refractory to anti-TNFs achieve disease remission with tocilizumab plus metho  Jun 14, 2008
    The RADIATE study was a randomised, double-blind study of 499 patients with moderate to severe RA. 12-18% of patients had 3 or more prior anti-TNF failures. A low proportion of the patients in the 8mg/kg tocilizumab group experienced serious adverse effects (6%) or serious infections (5%) during the trial. (EurekAlert!)

    Antibiotics can prevent wound complications of childbirth, Stanford/Packard study finds  Jun 10, 2008
    Duggal, Daniels and El-Sayed conducted a randomized, double-blind study in 147 women who experienced third- or fourth-degree tears while delivering infants at either Packard Children's Hospital or Santa Clara Valley Medical Center. After agreeing to participate in the study, the women were randomly assigned to receive a one-time intravenous infusion of either antibiotic or placebo during the repair of their tear. (EurekAlert!)

    Study finds Chinese food good for your heart  Jun 9, 2008
    The multicenter, randomized, double-blind study, was conducted on almost 5,000 patients, ranging in age from 18-70 over a five-year period at over 60 hospitals in the People's Republic of China. Corresponding author David M. Capuzzi, M.D., Ph. (EurekAlert!)

    New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study  Jun 8, 2008
    In this double-blind study, patients were randomized to receive for 13 weeks, either AVE0010 subcutaneously at the doses of 5, 10, 20 and 30 micron(g) once daily or twice daily, or placebo. The primary endpoint was change in HbA1c from baseline. (PR Newswire)

    Aliskiren Combined with Losartan in Type 2 Diabetes and Nephropathy  Jun 5, 2008
    Methods We enrolled 599 patients in this multinational, randomized, double-blind study. After a 3-month, open-label, run-in period during which patients received 100 mg of losartan daily, patients were randomly assigned to receive 6 months of treatment with aliskiren (150 mg daily for 3 months, followed by an increase in dosage to 300 mg daily for another 3 months) or placebo, in addition to losartan. (New England Journal of Medicine)

    Research Advances May Help Prevent And Improve Diagnosis Of Celiac Disease  May 22, 2008
    A new therapy may protect patients with celiac disease from exposure to gluten, according to findings from the first double-blind study ever conducted on celiac disease. Celiac sprue is a digestive disease that damages the small intestine and disrupts the absorption of nutrients from food. (Science Daily)

    Could Common Pain Killers Have A Role In Cancer Prevention?  May 21, 2008
    In this three-year, randomized, placebo-controlled, double-blind study, investigators sought to determine if the use of a chemopreventive drug could reduce adenoma (benign tumor) burden. The study followed 1,561 adenoma-prone patients in 32 countries to determine if patients treated with a single 400-mg daily dose of celecoxib (twice the approved osteoarthritis dose) had lower rates of benign polyps than those treated with a placebo. (Science Daily)

    Eye Cell Implants Improve Parkinson's Symptoms  May 2, 2008
    Bakay said the researchers have recently completed a larger, double-blind study, and results of that trial should be available by the end of this year or early 2009. HealthDay. (MEDLINEplus)

    Continuous use of birth control studied  Apr 9, 2008
    Researcher Richard Legro compared the continuous contraceptive's effectiveness at suppressing the ovary against the typical 28-day birth control in a double-blind study that assigned 62 women to receive one of the two methods. Quality of life, bleeding, suppression of the ovary and the lining of the uterus were observed in each woman for six months. (Daily Collegian, PA)

    Viper venom examined to save stroke sufferers  Apr 9, 2008
    But neither he nor Chui knows whether he got the drug because it is being used in a double-blind study against a placebo. No one knows who is receiving what. (USA Today)

    Breast Cancer Drug Good Later Than Thought  Mar 17, 2008
    Plus, this wasn't a randomized, double-blind study. The patients actually chose their treatment. (CBS News -- Early Show)

    Self Experimenters: To Purge Binges, Alcoholic Cardiologist Self-Prescribed an Experimental Drug  Mar 15, 2008
    But, contrary to Ameisen's experience, a recent double-blind study of 80 alcoholics at the University of North Carolina School of Medicine in Chapel Hill found no difference in outcome between those taking baclofen or a placebo. Ameisen points out, however, that the dosage of 30 milligrams a day given to study participants was far lower than his up to 270-milligram daily dose, which studies had shown people could tolerate without displaying side effects such as somnolence and muscle weakness. (Scientific American)

    Experimental MS Drug Shows Promise, Offers New Window On Disease, Study Shows  Feb 17, 2008
    16, 2008) A drug therapy currently used to treat non-Hodgkin's lymphoma and rheumatoid arthritis had a significant effect in treating the most common form of multiple sclerosis in a small, short-term clinical trial. Because the drug targets the immune system's B-cells, rather than the immune system's traditionally targeted T-cells -- long considered the primary culprit -- the finding provides a new insight into the cause of the disease, the researchers say. (Science Daily)

    Vicriviroc Demonstrates Potent and Sustained Viral Suppression Through 48 Weeks of Therapy in Treatment-Experienced HIV-Infected Patients  Feb 7, 2008
    A total of 116 treatment-experienced adult HIV-infected patients with R5-type virus at screening were randomized in this placebo-controlled, double-blind study at 37 sites throughout Europe, South Africa and North and South America. Results of the study through 48 weeks demonstrated potent and sustained viral suppression in the vicriviroc arms, with significantly greater decreases in mean HIV-RNA, as well as greater increases in mean CD4 counts, compared to the control arm. (PR Newswire)

    Win, place, or cell  Jan 26, 2008
    In the Winter 2007 issue of Veterinary Therapeutics, they on a randomized, double-blind study of dogs with chronic osteoarthritis of the coxofemoral joints. The conclusion: "This multicenter study shows that intraarticular administration of adipose-derived stem and regenerative cell therapy decreases patient discomfort and increases patient functional ability." Owners of three of the dogs participating in the study were considering euthanasia before the dogs were treated, and those three dogs... (The Scientist)

    Local doctors receive national attention  Jan 21, 2008
    ryeguy wrote on Jan 21, 2008 6:48 AM:" I developed allergies in college, had shots for several years, and that did it for 20 years. When allergies re-developed I went to Dr. Morris's clinic. I have to say that sub-lingual drops did nothing for me. After some time, I switched allergists to get shots, and they worked fine. Years later I am still essentially allergy free. My guess is that shots work better for some people for some allergies, and sub-lingual may work better for others for some... (La Crosse Tribune, WI)

    Judge Kosel to retire, plans to stay active  Jan 17, 2008
    It's a double blind study and I don't know if I'm getting the placebo or a creatine enzyme. It may benefit me, but if not, the study will hopefully help others who suffer from Parkinson's. (Mount Shasta News, CA)

      - The Year That Was 2007  Jan 1, 2008
    In fact, EPA scientists in the trenches will tell you that there has not been any double-blind study of fluorides effectiveness as a caries preventative (see , paragraph 14). That fluoridating the drinking water supply is dangerous to peoples health is not a belief, as is being reported here and in testimony before the County Commission by someone who should know better County Health Officer Howard Leibrand. (Anacortes Weekly, WA)

    Medical Myths Even Doctors Believe  Dec 27, 2007
    Was the scientific study a double-blind study. How many participants were there. (New York Times)

    Effective New Treatment for Schizophrenia  Dec 14, 2007
    Dr. Stephen Marder, senior author on the paper, explains the findings: This double-blind study found that two doses of paliperidone extended release tablets were more effective than placebo for treating the symptoms of acute schizophrenia. Patients receiving the most effective dose of paliperidone (6 mg) also demonstrated improvements in their social functioning. (Newsmax)

    Pre00002E1Dscription For Addiction  Dec 8, 2007
    There is a placebo-controlled, double-blind study under way that will apparently support some of Prometas claims, but it was run by a researcher who also owns an addiction clinic that uses Prometa, among other treatments. He denies there is any conflict. (CBS News -- 60 minutes)

    Honey Gives Kids Sweet Relief From Coughs  Dec 5, 2007
    The researchers enrolled 105 children, between ages 2 and 18, in their randomized, partially double-blind study. On the first night of the study, the children received no treatment. (ABC News)

    Torcetrapib in Patients at High Risk for Coronary Events  Nov 22, 2007
    Methods We conducted a randomized, double-blind study involving 15,067 patients at high cardiovascular risk. The patients received either torcetrapib plus atorvastatin or atorvastatin alone. (New England Journal of Medicine)

    Cell transplants may improve severe urinary incontinence  Nov 13, 2007
    In the double-blind study, self-donated (autologous) myoblast muscle cells were taken from the leg muscles of female laboratory rats and transplanted into their nerve-damaged and muscle-weakened sphincter muscles. A control group with the same urethral muscle deficiency received saline injections. (EurekAlert!)

    University Hospitals Case Medical Center finds new treatment holds promise for Tourette syndrome  Nov 13, 2007
    The UHCMC teams prospective double-blind study followed these five adults with TS over the course of 12 months ... In this double-blind study the electrodes were placed in the thalamus, a portion of the brain that is involved in controlling movement. (EurekAlert!)

    New Data Presented at ACAAI Informs on the Safety and Efficacy of Nasacort AQ Nasal Spray in a Trial of Children Aged 2-5 Years Old with Year-Round Allergic Rhinitis  Nov 11, 2007
    Caused by an allergic reaction to allergens such as house dust, animal dander, or pollen, allergic rhinitis is the most common chronic childhood disease, effecting as many as 40% of all children in the U.S. A clinical study suggests that Nasacort AQ may present a safe and effective treatment option in children aged 2-5 years with year-round allergic rhinitis In a multicenter, randomized, double-blind study, Nasacort AQ, given as 1 spray per nostril once daily for 4 weeks, improved combined... (PR Newswire)

    Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]  Nov 1, 2007
    The efficacy and safety of a dietary supplement derived from South American botanicals was compared to glucosamine sulfate in osteoarthritis subjects in a Mumbai-based multi-center, randomized, double-blind study. Methods. (BioMed Central)

    New study of Concerta showed significant improvement of ADHD symptom management in adults  Oct 27, 2007
    A similar dose titration protocol was used as in the double-blind study during the first weeks of the study after which the dose was flexible within the range of 36 to 108 mg. Interim results show that CONCERTA was well tolerated in an adult population with ADHD in a dose range from 36mg to 108 mg per day for up to six months. . (EurekAlert!)

    Labopharm completes enrolment for Phase III clinical study for its once-daily trazodone antidepressant drug  Sep 25, 2007
    Study 04ACL3-001 is a randomized, double-blind study which compares the efficacy and safety of Labopharm's once-daily formulation of trazodone to placebo in patients with major unipolar depressive disorder. The study, which has a treatment period of approximately two months, is being conducted at more than 35 centers across the U.S. and Canada. (Canada Newswire)

    Study Shows Hyperactivity Linked to Diet  Sep 24, 2007
    In an authoritative, double-blind study, the Brits have proved contrary to food industry skepticism that common food dyes as well as the food preservative sodium benzoate can trigger hyperactivity in many children ... In a controlled, double-blind study carried out over three one-week periods, the children were given one of three fruit drinks that all tasted exactly alike. (Newsmax)

    Amino Acid May Cure Gambling Addiction  Sep 17, 2007
    A small double-blind study found that 83 percent of volunteers who took the amino acid reported fewer impulses to gamble. When people responded, which was the majority of people, they responded quite robustly, said Dr. Jon Grant, the studys lead investigator. (Newsmax)

    U of M study: Health food supplement may curb addiction of pathological gamblers  Sep 12, 2007
    Those who responded well in the first round of the study were asked to continue to participate in a double-blind study a testing method where neither the researcher nor subjects know who is in the control group until the study is finished. Of the 16 who responded to the amino acid the first time around, 13 agreed to continue in the double-blind study (three didnt want to risk quitting the drug) for an additional six weeks. (EurekAlert!)

    Cholesterol-lowering statins may help prevent Alzeimer's, too, study suggests  Sep 4, 2007
    Nevertheless, Dr. Dwork said, "This is an interesting study and it's important to do this kind of work, especially because you're in a situation where it's difficult or impossible to do a randomized, double-blind study.". Another researcher not involved in the work, Peter Zandi, an assistant professor of psychiatric epidemiology at the Johns Hopkins Bloomberg School of Public Health, said the study encouraged further investigation of the potential effects of statins, but like Dr. Li, he... (International Herald Tribune -- Health)

    Heart Damage Can Be Reversed with Early Treatment  Aug 29, 2007
    In a recent double-blind study, researchers enrolled 76 asymptomatic subjects with early markers for cardiovascular disease, based on a 10-factor scale called the Rasmussen Disease Score. During the first six months of the study, 38 subjects received a placebo, and the other 38 subjects took 160mg of Valsartan, a drug that blocks a hormone that is detrimental to the blood vessels and the heart. (Science Daily)

    Frovatriptan may prevent puncture-related headache  Aug 25, 2007
    Nevertheless, they conclude, their findings suggest frovatriptan can be effective, and they recommend that this should be tested in a randomized, controlled, double-blind study. SOURCE: Cephalalgia, July 2007. (Scientific American)

    Placebo Effect Seen in Kids During Allergy Testing  Aug 15, 2007
    A double-blind study is when the doctor and the patients do not know which is the placebo and which is the real medicine. The researchers examined the occurrence and features of placebo reactions after 132 challenges in 105 children (average age 5. (MEDLINEplus)

    Labopharm reports results for second quarter fiscal 2007  Aug 9, 2007
    Study 04ACL3-001 is a randomized, double-blind study that will compare the efficacy and safety of the Company's once-daily formulation of trazodone to placebo in patients with major unipolar depressive disorder. The study is being conducted at more than 35 centers across the U.S. and Canada and is expected to include more than 350 subjects. (Canada Newswire)

    Quebec refuses to force chemo on 3-year-old boy  Jul 28, 2007
    Terry wrote on July 27, 2007 at 1:52:56 PM The fact is Homeopathy is a COMPLETE SHAM. There isn't one double blind study done to back up their claims. In fact homeopathists are eligible for the James Randi $1,000,000 prize if they can prove their magic water really works. (CTV.ca)

    ACE Plus ARB Found to Equal Lower Blood Pressures  Jul 21, 2007
    The double-blind study included 1,797 men and women, 18 and older, with hypertension (mean sitting diastolic blood pressure 95 to 109 mm Hg). Almost 60% of the patients had stage 2 hypertension, and almost half were obese. (MedPage Today)

    Both entrepreneurial, managerial styles bring success  Jun 21, 2007
    "It takes a balance. An entrepreneur acts on gut feelings and is looking for a paradigm shift, whereas a professional manager looks to improve an existing system and wants data from a double-blind study to make decisions," Rhode said. "There comes a point where you have to take on professional managers who complement your strengths," he said. (Phoenix Business Journal, AZ)

    Actemra: Roche's Novel Rheumatoid Arthritis Drug Shows Substantial Benefits for Patients in OPTION Study  Jun 15, 2007
    About the OPTION study The OPTION (TOcilizumab Pivotal Trial in Methotrexate Inadequate respONders) study was an international study involving 623 patients with moderate to severe RA. In this 3-arm, randomized, double-blind study, patients received tocilizumab intravenously (either 4mg/kg or 8mg/kg) every 4 weeks plus methotrexate weekly or placebo infusions plus methotrexate weekly over a period of 6 months. Although higher efficacy was established at the higher dose (ACR20, 50 and 70 scores of... (Canada Newswire)

    Labopharm Initiates Phase III Clinical Study for Once-Daily Formulation of Trazodone  Jun 7, 2007
    "Depression is one of the most prevalent central nervous system disorders, affecting at least 121 million people globally, and trazodone is widely used in its treatment with more than 14 million prescriptions written in the U.S. alone in 2006," said James R. Howard-Tripp, President and Chief Executive Officer, Labopharm Inc. "Insomnia and agitation may be associated with depression. In addition to its anti-depressive effects, trazodone has sedative effects that can improve sleep. Our once-daily... (Canada Newswire)

    Hormone that signals fullness also curbs fast food consumption and tendency to binge eat  Jun 7, 2007
    Multi-center, double-blind study. Eighty eight volunteers, comprised of obese men and obese post-menopausal women, 25-60 years old, took part in the 6-week study. (EurekAlert!)

    GLAXOSMITHKLINE REPORTS POSITIVE NEW DATA ON TYKERB(R)(LAPATINIB) AT THE 2007 AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO) ANNUAL MEETING  Jun 4, 2007
    Di Leo et al. Abstract #1011 - Lapatinib (L) with paclitaxel compared to paclitaxel as first-line treatment for patients with metastatic breast cancer: A phase III randomized, double-blind study of 580 patients. Presented at the 2007 American Society of Clinical Oncology annual meeting. (PR Newswire)

    Investigational nonstimulant Guanfacine XR significantly improved child, adolescent ADHD symptoms  May 24, 2007
    APA Poster # NR656 Wednesday, May 23, 2007 at 12 p.m. PDT (3 p.m. EDT) Randomized, Double-Blind Study of Guanfacine Extended Release in Children Aged 6 to 17 Years With Attention-Deficit/Hyperactivity Disorder (Trial 304) F. Sallee, M.D.; J. McGouth; T. Wigal, Ph. D.; J. Donahue, M.P.H.; A. Lyne, M.S.C.; J. Biederman, M.D.. (EurekAlert!)

    New Study Results Provide Additional Data about Short- and Long-Term Use of Desvenlafaxine Succinate in the Treatment of Adults with Major Depressive Disorder  May 22, 2007
    The most frequent cause for discontinuation of treatment in the double-blind study was depression, reported by 4 percent of patients who took desvenlafaxine succinate and 8 percent of placebo patients ... The double-blind study population included 375 adults, 18 to 75 years old, with a primary diagnosis of MDD who participated in an initial 12-week, open- label study of desvenlafaxine succinate at doses ranging from 200 to 400 mg/day (desvenlafaxine succinate group, n=190; placebo group, n=185)... (PR Newswire)

    Retinol lotion reduces the fine wrinkles from natural aging of skin  May 22, 2007
    This is the first systematic, double-blind study showing that it improves any kind of aging photoaging as well as natural aging, says co-author John J. Voorhees, M.D., the Duncan and Ella Poth Distinguished Professor and chair of the Department of Dermatology at the U-M Medical School. You can rub it anywhere, and it will help to treat the signs of aging. (EurekAlert!)

    In this thriller, the patients lose patience  May 17, 2007
    In his fourth novel , Skloot introduces us to a plucky, colorful group of patients participating in a double-blind study of a new drug at an Oregon medical school. Skloot's novel is part critique of conventional medicine, part love story, part mystery, part heist caper, and part New Age comedy. (Boston Globe)

    Institute zeroes in on Alzheimer's  May 7, 2007
    By mid-year, the institute hopes to continue the Ireland trial with a double-blind study, meaning neither patients nor doctors know who gets Nilvadipine and who gets a placebo until they conclude. That study, which would involve about 200 people, could cost $20 million, Roskamp said. (Herald-Tribune)

    Gleevec decreases cancer recurrence for patients with primary gastrointestinal stromal tumor  Apr 13, 2007
    Z9001: A Phase III Randomized Double-blind Study of Adjuvant STI571 (Gleevec) Versus Placebo in Patients Following the Resection of Primary Gastrointestinal Stromal Tumor (GIST). The protocol for this study can be found at. (EurekAlert!)

    Study Provides New Safety & Efficacy Data For Unique Anti-anginal Therapy  Mar 29, 2007
    The placebo-controlled, double-blind study enrolled 6,560 ACS patients at 440 sites in 17 countries whose EKG tests showed no ST elevation, indicating some artery blockage due to a blood clot, but not total blockage of the artery. All were treated with standard of care, including aspirin, beta-blockers, an oral anti-platelet, and anti-coagulant; many also had angioplasty or other coronary surgical procedures. (Science Daily)

    Degrees in homeopathy slated as unscientific  Mar 29, 2007
    Bushwacked and suppressed by drug companies for the illusion of the double blind study. All double blind studies show is that a goup of people will be toxified in the same manner by the same drug in the same dosage. (Nature News Service)

    Bacteria from patient's dental plaque causes ventilator-associated pneumonia  Mar 24, 2007
    The presentation is part of a three-year longitudinal, double-blind study funded by the National Institute of Dental and Craniofacial Research and headed by Frank A. Scannapieco, D.D.S., Ph. D., professor and chair of the Department of Oral Biology. (EurekAlert!)

    SEROQUEL(R) Sustained Release Schizophrenia Data Presented at ECP Congress in Madrid  Mar 18, 2007
    A randomized, double-blind study of 588 patients with acute schizophrenia (Study 132) compared SEROQUEL(R) sustained release formulation (400 mg/day, 600 mg/day or 800 mg/day) with placebo and found a significant improvement in Positive and Negative Syndrome Scale (PANSS) total scores from baseline for all doses. (1) After 6 weeks of treatment, reductions of 24. (Canada Newswire)

    Insomnia Drug Can Improve Brain Function In Certain Patients  Mar 14, 2007
    All of these were conducted with both zolpidem and a placebo in a randomized, double-blind study. The results showed that after receiving zolpidem, the patient was able to stand up and walk, repeat words and sentences, read words, and name objects, although she was not able to speak spontaneously. (Science Daily)

    Treatment of Restenosis with a Paclitaxel-Coated Balloon Catheter  Mar 8, 2007
    First, the trial was reported to be a double-blind study, but the investigators were aware of assignments to study groups because the paclitaxel-coated balloons were a different color from the uncoated balloons. The reduction in major cardiac events in patients who received treatment with a paclitaxel-coated balloon was driven primarily by a reduction in target-lesion revascularization, a subjective end point that was based on symptoms. (New England Journal of Medicine)

    Two Inhalers Are Better Than One For Common Lung Disease  Mar 7, 2007
    The randomized double-blind study followed 449 patients for one year in 27 hospitals and medical centres across Canada. Patients who received SpirivaTM and AdvairTM scored twice as high in a quality of life assessment compared to patients taking SpirivaTM and placebo. (Science Daily)

    Actelion: Positive Study With Bosentan (Tracleer) in CTEPH  Mar 5, 2007
    In this first-ever double-blind study in a patient population suffering from this form of pulmonary hypertension, the six-minute walk test remained stable over the four months of blinded evaluation in both treatment groups. Patients on bosentan showed a significant improvement in breathlessness (Borg dyspnoea score) with exercise and there was a trend in favor of bosentan towards prevention of worsening WHO functional class. (Primezone Releases)

    Breath test able to spot lung cancer  Feb 27, 2007
    A double-blind study published last year found dogs had a 99 per cent accuracy rate when detecting patients with lung cancer. send photos, videos ffs to 0424 SMS SMH (+61 424 767 764), or us. (Sydney Morning Herald)

    Garlic doesn't unclog arteries  Feb 27, 2007
    In the double-blind study, part of the group was given dummy pills. While more than half of the participants reported bad breath and body odor and some reported flatulence, there were no major side effects from eating garlic. (Pittsburgh Post-Gazette, PA)

    Drug Controls High-altitude Illness  Feb 21, 2007
    (January 4, 2007) -- Long-acting octreotide does not improve outcomes for patients with liver cancer compared to a placebo, according to the results of a new double blind study published in the January 2007 issue of. . (Science Daily)

    Morphine shown to ease coughs  Feb 18, 2007
    ----------------- ----------------- RELATED BBC SITES. Last Updated: Sunday, 18 February 2007, 00:06 GMT. (BBC News -- UK)

    Attention Deficit Disorder  Feb 16, 2007
    Tragically--the "epidemic" having grown from 500 thousand in 1985 to between 5 and 7 million today--this remains the state of the 'science' of ADHD." Breggin (1991), comments on the wraparound model used by Youth Advocate Programs. Breggin states that direct psychosocial interventions into the home are very useful. Breggin notes that Youth Advocate Programs was initially established in 1975, and delivers community based services to children with serious psychiatric diagnoses. Breggin mentions... (Suite101.com)

    Your Health This Month:  Feb 14, 2007
    This is the double-blind study model (though the blinding may be more apparent than real, since anyone who has ever administered the shots will tell you that the patients almost always know what they are getting). Results: In any case, according to both patients' self-reports and objective measures like decreased need for medications like antihistamines and nasal steroids, was shown to be unquestionably beneficial. (Slate)

    Herbal remedies a help in menopause?  Feb 13, 2007
    Participants signed on to the double-blind study for one year and were given either black cohosh, soy, a mix of herbal supplements, a placebo or actual hormone therapy. After 2002, when the damaging report about estrogen was made known, those taking hormones were given the option of stopping treatment, and no new enrollees were given estrogen. (Newsday -- Health)

    Extra cortisol protects women's mood under stress  Feb 12, 2007
    Psychologists Serkan Het, MSc, and Oliver Wolf, PhD, of the University of Bielefeld, enlisted 44 healthy women for a double-blind study, in which neither researchers or participants knew the condition to which the women were assigned. One hour before a psychosocial stress test, participants were given either a 30 mg. dose of oral cortisol or a placebo. (EurekAlert!)

    Vitamins: Science Doesn't Always Match Policy  Feb 7, 2007
    (May 20, 1997) -- Simply taking antioxidant vitamins could help asthmatics exposed to polluted air breathe easier, according to preliminary results of a double blind study conducted at the University of Washington. . (Science Daily)

    No More Seizures? New Drug Holds Promise For Epilepsy Patients  Feb 7, 2007
    For the multi-center, double-blind study, researchers assigned nearly 600 adults who had at least two seizures in the previous year to the drug levetiracetam or to controlled-release carbamazepine, a common epilepsy treatment. While levetiracetam is currently used as an add-on therapy by epilepsy patients, this is the first time its effectiveness as a single therapy has been tested through a clinical trial that provided class 1 evidence of efficacy as defined by the International League Against... (Science Daily)

    Brain Stents Might Help High-Risk Stroke Patients  Feb 7, 2007
    But he added that, "what you want at the end of the day is a double-blind study" comparing stent implantment with other treatments for high-risk persons, such as those with severely narrowed arteries and conditions such as diabetes, high blood pressure and a prior stroke. At this time, the treatment such people receive depends in large part on the resources available at the center where they are diagnosed, Kenton said. (MEDLINEplus)

    Key Medical Journal Publishes New Strategy Against Drug Resistant Germs  Feb 1, 2007
    The results of treating infected mice in a double blind study at the University of Arizona with Bioengineered Lacteal Complex (BLC) is published as "A Pilot Study of an anti-MRSA Bio-Engineered Lacteal Complex (anti-MRSA BLC) in a Murine Septicemia Model" co-authored by Jesse A. Stoff, MD, David E. Nix, MD and D.W. DeYoung, DVM in the new issue of the journal "Immunopharmacology and Immunotoxicology" released on December 29, 2006. In the face of this evolving threat an Arizona company, Immune... (PR Newswire)

    Coffee and Pregnancy Mix Safely  Jan 27, 2007
    In a randomized double-blind study of more than 1,000 pregnant women, there was no evidence that the caffeine in three cups a day had any effect on the outcome of the pregnancy, found Bodil Hammer Bech, Ph. D., of the Institute of Public Health at the University of Aarhus. (MedPage Today)

    The New England Journal Of Medicine Publishes Two Landmark Studies Of NOXAFIL(R) (Posaconazole) in the Prevention of Invasive Fungal Infections  Jan 25, 2007
    Posaconazole or Fluconazole for Prophylaxis in Severe Graft-versus-Host Disease (Ullmann et al.): This randomized, multicenter, double-blind study compared NOXAFIL Oral Suspension 200 mg three times daily (n=301) to fluconazole capsules 400 mg once daily (n=299) as prophylaxis against IFIs in allogeneic hematopoietic stem cell transplant (HSCT) recipients with graft- versus-host disease (GVHD). At the end of the fixed 112-day treatment period, NOXAFIL versus fluconazole demonstrated a reduction... (PR Newswire)

    Drugs take bite out of bad behavior  Jan 16, 2007
    In 2001, Gray saw a small newspaper ad: "Spraying Cats Needed for Study." Shadow was accepted into a double-blind study of an undisclosed medication's effect on the behavior. Fourteen days later, the spraying abruptly stopped. (FOX59, IN)

    Basilea Announces Positive Top-Line Results On Second Pivotal Phase III Ceftobiprole Trial  Jan 10, 2007
    This second pivotal double-blind study (STRAUSS II -- study of resistant Staphylococcus aureus in complicated skin and skin structure infections) treated 828 patients with either ceftobiprole or the combination of ceftazidime plus vancomycin in a 2:1 randomization. Almost one third of patients had diabetic foot infections of which three quarters were moderate to severe cases. (Primezone Releases)

    New therapy for chronic fatigue syndrome to be tested at Stanford  Jan 9, 2007
    3 million grant from Roche Pharmaceutical, which manufactures the drug under the brand name Valcyte, to conduct a randomized, placebo-controlled, double-blind study set to begin this quarter at Stanford. The study will assess the effectiveness of the drug in treating a subset of CFS patients. (EurekAlert!)

    Prenatal Vitamins for Malnourished Moms Improve Birth Weight  Jan 6, 2007
    The double-blind study was conducted at a tertiary care hospital that serves poor residents from nearby urban slums and rural communities. Only women who lived within three miles of the hospital were enrolled. (MedPage Today)

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