SurfWax News Index  |  Track News  |  Save/Exchange Information |  About Us News and Articles on Cytochrome P 450 Marketing Of Unproven Genetic Tests A Threat To Public Health  Apr 9, 2008 The authors reviewed claims made by testing businesses about the value of genetic testing for variability in cytochrome P-450 (CYP450) enzymes in predicting how individuals will metabolize antidepressants called selective serotonin reuptake inhibitors (SSRIs). At least 15 businesses currently offer CYP450 genotyping services, and four of those companies make specific claims that a CYP450 test can be used to recommend treatment, drug choice, and dosage. (Science Daily) Genetic Determinants of Response to Warfarin during Initial Anticoagulation  Mar 6, 2008 Background Genetic variants of the enzyme that metabolizes warfarin, cytochrome P-450 2C9 (CYP2C9), and of a key pharmacologic target of warfarin, vitamin K epoxide reductase (VKORC1), contribute to differences in patients' responses to various warfarin doses, but the role of these variants during initial anticoagulation is not clear. Methods In 297 patients starting warfarin therapy, we assessed CYP2C9 genotypes (CYP2C9 *1, *2, and *3), VKORC1 haplotypes (designated A and non-A), clinical... (New England Journal of Medicine) Medicinal importance of grapefruit juice and its interaction with various drugs  Oct 31, 2007 Other articles by authors. Related articles/pages. (Nutrition Journal) Telithromycin in Acute Exacerbations of Asthma  Jul 6, 2006 Telithromycin is a strong inhibitor of cytochrome P-450 isoenzyme 3A4 (CYP3A4). 3 Two inhaled corticosteroids that are commonly used in clinical practice (budesonide and fluticasone). (New England Journal of Medicine) Back to Chemistry News [ Terms Of Use | Privacy | About ] ©1998-2008 SurfWax, Inc. All rights reserved. Patents pending. Copyright SurfWax, Inc. 2008