Curry as Cure? Spicing Up the Effectiveness of a Potential Disease-Fighter Nov 17, 2009
Takahashi et al. Evaluation of an Oral Carrier System in Rats: Bioavailability and Antioxidant Properties of Liposome-Encapsulated Curcumin. Journal of Agricultural and Food Chemistry, 2009; 57 (19): 9141 DOI. (Science Daily)
Myriad Pharmaceuticals Reports First Quarter FY' 2010 Financial Results Nov 13, 2009
-- Sept. 14, 2009, the Company presented data at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) Annual Meeting demonstrating safety and bioavailability of the new solid tablet formulation of the Company's HIV drug candidate MPC-4326. -- June 30, 2009, Myriad Pharmaceuticals completed its separation from Myriad Genetics, Inc. through a pro rata dividend distribution to the stockholders of Myriad Genetics. (Primezone Releases)
Medical patent builds Orange Park business Oct 20, 2009
There is good reason for interest in the RZN process, which protects beneficial phytochemicals of herbs and herbal extracts from being digested before entering the bloodstream, resulting in improved bioavailability to the body ... With the advances in absorption offered by HerbaZorb, we can ensure that everyone in the industry using herbal blends can benefit from maximum bioavailability so the active ingredients in them are utilized most fully by the human body, Lubin said. (Jacksonville Business Journal, FL)
Myriad Pharmaceuticals Announces the Identification of an IND Candidate for the Treatment of Cancer, Obesity, and Diabetes Oct 14, 2009
Myriad Pharmaceuticals' IKK epsilon antagonist and IND candidate, MPI-0485520, is a selective and potent inhibitor of IKK epsilon, with high oral bioavailability and demonstrated on-target, in vitro and in vivo biological activity. Myriad Pharmaceuticals' IKK epsilon program was originally launched to exploit the potential of IKK epsilon as a novel oncology target. (Primezone Releases)
Novel, soy-based SE5-OH containing Natural S-equol supplement reduced hot flash frequency by nearly 59 percent Oct 9, 2009
SE5-OH Containing Natural S-equol Supplements Provide Very High Systemic Bioavailability. The S-equol in SE5-OH containing Natural S-equol supplement tablets was rapidly absorbed from the tablets and attained optimal concentrations in the blood stream, providing very high systemic bioavailability when given to healthy postmenopausal women ... Bioavailability is a calculation of how much of a given dose of a test compound reaches the blood stream to circulate within the body, has a potential... (EurekAlert!)
Researchers look to enriched crops to solve childhood malnutrition Sep 30, 2009
Current experiments seek to determine the bioavailability of the additional nutrients they added to cassavameaning whether the body can absorb themby feeding the cassava first to a type of intestinal cell grown in a dish, followed by mice and finally humans. It could take two years before human trials begin. (Washington University Student Life, MO)
Total Number of Voting Rights and Size of Share Capital in LifeCycle Pharma A/S As of September 30, 2009 Sep 30, 2009
LCP's unique, patented delivery technology, MeltDose(R), can improve absorption and bioavailability -- at low-scale up costs -- not only for a broad spectrum of drugs already on the market but also for new chemical entities. LCP has a cholesterol-lowering product, Fenoglide(R), currently on the U.S. market and a diversified near- and medium-term pipeline with four product candidates in clinical trials and a number of projects in preclinical development. (Primezone Releases)
Erin Brockovich encourages residents to voice concerns Sep 25, 2009
Part of me wants to tell you that smoke and mirrors (the big language that lawyer types and self appointed conservationists use for shock and awe) can misdirect the uneducated; then again, part of me wants to tell you about bioavailability and chemical compounds that classify the lead source itself. I havent seen one quote of a Doe Run spokesperson minimizing the issue at hand. (Park Hills Daily Journal, MO)
Nektar Presents Data Demonstrating Favorable Oral Bioavailability and Drug-Drug Interaction Profile for NKTR-118 Sep 14, 2009
Sept. 13 /PRNewswire-FirstCall/ -- Nektar Therapeutics (Nasdaq: ) presented clinical study data today demonstrating that the oral tablet formulation of NKTR-118 has favorable systemic bioavailability and a low risk for mediating significant drug-drug interactions ... Nektar's proprietary advanced polymer conjugate technology increases the bioavailability and half-life of naloxol, enabling NKTR-118 to act selectively in the periphery while preserving centrally-mediated opioid analgesic clinical... (PR Newswire)
How To Boost Value Of Alzheimer's-fighting Compounds Sep 8, 2009
Bioavailability of Gallic Acid and Catechins from Grape Seed Polyphenol Extract is Improved by Repeated Dosing in Rate: Implications for Treatment in Alzheimer's Disease. Journal of Alzheimer's Disease, September 2009. (Science Daily)
Bioavailable Contaminants Come From Exxon Valdez Oil Catastrophe; Natural Coal Deposits Not Source Of Environmental Pollution, Study Finds Sep 2, 2009
Their bioavailability thus determines their toxicity. They are generally only bioavailable if the substances are water-soluble. (Science Daily)
Antibiotic Resistance in Dogs and C... Aug 26, 2009
decreased bioavailability of the antibiotic, such as that which may occur when other drugs or food interfere with the absorption or metabolization of the antibiotic being administered. choosing the wrong antibiotic, such as choosing an antibiotic which does not reach adequate levels in the tissue which is infected or choosing an antibiotic which is not effective against the organism present. (Suite101.com)
Tobira Therapeutics Inc. Announces Phase I Data Demonstrating Pharmacokinetic Properties of TAK-652 for the Treatment of HIV Jul 22, 2009
PRINCETON, N.J. and SAN DIEGO, July 22 /PRNewswire/ -- Tobira Therapeutics Inc., a clinical stage biotechnology company committed to research and product discovery for the treatment of life-threatening and life-altering infectious diseases, today announced pharmacokinetic data and results from two Phase I pharmacokinetic studies for TAK-652, an investigational compound being developed for the treatment of HIV. These data suggest that TAK-652 is rapidly absorbed and demonstrate relatively good... (PR Newswire)
Scientists Characterizes New Syndrome Of Allergy, Apraxia, Malabsorption Jul 16, 2009
While low vitamin E bioavailability may occur due to a variety of different causes, neurological consequences are similar, regardless of the initiating trigger. The study suggests that vitamin E could be used as a safe nutritional intervention that may benefit some children. (Science Daily)
XOMA Announces Positive Results From U.S. Phase 1 Trial of XOMA 052 in Type 2 Diabetes Jul 15, 2009
Pharmacokinetic results continue to support monthly or less frequent dosing and drug bioavailability in patients by subcutaneous injection was 62-70% compared to IV administration ... "Taken together, these data demonstrate, as expected, the potential for added benefit with multi-dose treatment using XOMA 052. In addition, the 0.03 mg/kg multiple dose median reduction of over 50% in CRP and up to 0.6% in HbA1c at day 56 compares favorably to reductions of 29% and 0.3%, respectively, for a single... (Primezone Releases)
Easter Island Compound Extends Mouse Lifespan Jul 9, 2009
He worked with the Southwest Research Institute in San Antonio to improve the bioavailability of the compound through a process called microencapsulation. The reformulated drug was stable in the diet fed to the mice and bypassed the stomach to release in the intestine, where it could more reliably enter the bloodstream. (Science Daily)
Shape Matters In The Case Of Cobalt Nanoparticles Jul 5, 2009
21, 2006) One of the most common bacteria in the Earth, Shewanella oneidensis MR-1, influences the mobility and bioavailability of iron and environmental contaminants like lead, cobalt and arsenic. (July 11, 2007) Researchers have discovered how to make polymeric micro- and nanoparticles in a wide variety of different shapes and sizes using commonly-available lab chemicals and. (Science Daily)
Implant Bacteria, Beware: Researchers Create Nano-sized Assassins Jun 29, 2009
21, 2006) One of the most common bacteria in the Earth, Shewanella oneidensis MR-1, influences the mobility and bioavailability of iron and environmental contaminants like lead, cobalt and arsenic. (July 8, 2006) For the first time, engineers have created surfaces for orthopaedic implants that reduce the presence of bacteria. (Science Daily)
Latest Berry Health Benefits Revealed Jun 25, 2009
"Healthy Eating: Bioavailability of Dietary Flavonoids and Phenolics" ... "Berry Consumption in Humans: Bioavailability of Polyphenols and Effects on Cardiovascular Risk Factors". (PR Newswire)
UGA taps Cabrera as Georgia Power prof. May 22, 2009
He has conducted research on nitrogen processes associated with potential environmental contamination and has assessed the bioavailability of trace metals in soils amended with organic wastes. Professor Cabrera is one of the leading soil chemists in the world, said J. Scott Angle, dean and director of the UGA College of Agricultural and Environmental Sciences. (Atlanta Business Chronicle, GA)
Is dephytinization from infant cereals beneficial to the nutrition absorption? May 8, 2009
Given the importance of an adequate intake of minerals during infancy, Dr. Carmen Frontela and her colleagues in the University of Murcia (Spain) tested the effect of the dephytinization of three different commercial infant cereals on iron, calcium, and zinc bioavailability ... This study indicated that removing phytate from infant cereals had a beneficial effect on iron and zinc bioavailability when infant cereals were reconstituted with water ... Reference: Frontela C, Scarino ML, Ferruzza S,... (EurekAlert!)
How Mercury Emissions Reach Tuna And Other Seafood, And Why Mercury Contamination Is Likely To Worsen May 4, 2009
ScienceDaily (May 3, 2009) A new landmark study documents for the first time the process in which increased mercury emissions from human sources across the globe, and in particular from Asia, make their way into the North Pacific Ocean and as a result contaminate tuna and other seafood. Because much of the mercury that enters the North Pacific comes from the atmosphere, scientists have predicted an additional 50 percent increase in mercury in the Pacific by 2050 if mercury emission rates... (Science Daily)
Antioxidant Supplements in Cancer T... May 3, 2009
There have been concerns dealing with safety, efficacy and quality control of these products as well as concerns about proper dosage and bioavailability (how much of a product is actually present in a form that the animal is able to metabolize and benefit from). Antioxidant nutritional supplements do have a place in treating certain forms of cancer in pets, but a careful risk/benefit analysis should be made before starting an antioxidant nutritional supplement for an individual pet. (Suite101.com)
Minerals - Naturally Occurring Apr 17, 2009
Absorption occurs in the intestines and when taken in conjunction with certain vitamins will enhance its ability to be utilized by the body (bioavailability). For example, vitamin C taken with a meal improves iron absorption. (Suite101.com)
Neptune Technologies to expect Record Revenues; Fiscal 2009 Third Quarter and Year-End Results Apr 14, 2009
Human clinical study demonstrates superior Neptune Krill Oil NKO(R) pharmacokinetic profile NKO(R) achieved a significantly higher bioavailability compared to successfully marketed nutraceutical and pharmaceutical omega-3 and NKO(R) like phospholipid formulations supporting the claim of the superiority of Neptune's omega-3 phospholipids. Completion of $2. (Canada Newswire)
Cleaning Up Oil Spills Can Kill More Fish Than Spills Themselves Mar 18, 2009
"But in the short term, they increase the bioavailability and toxicity of the fuel to rainbow trout by 100-fold.". The detergents are oil dispersants that decrease the surface tension between oil and water, allowing floating oil to mix with water as tiny droplets. (Science Daily)
Emisphere Technologies, Inc. Complies With NASDAQ Marketplace Rule 4350(b)(1)(B) and Announces Filing of Annual Report On Form 10-K for 2008 Fiscal Year Mar 17, 2009
Such molecules are usually delivered by injection; in many cases, their benefits are limited due to poor bioavailability, slow on-set of action or variable absorption. The Eligen(r) Technology can be applied to the oral route of administration as well as other delivery pathways, such as buccal, rectal, inhalation, intra-vaginal or transdermal. (Primezone Releases)
Folic Acid Supplements Raise Prostate Cancer Risk Mar 12, 2009
"Folic acid, the synthetic version, has more bioavailability, meaning that the effective dose in the cell is higher than what you get from natural sources.". Dietary sources of folic acid in the United States now include cereals and other grain products. (MEDLINEplus)
Vitamin C Protects Blood Vessels Mar 11, 2009
Vitamin C improves the bioavailability of Iron by maintaining it in the reduced form which is more soluble and easily absorbed. It is also a free radical scavenger. (Suite101.com)
Moderate Alcohol Intake Protects Bones Mar 5, 2009
The authors hypothesize that the silicon found in beer is contributing to the higher BMD scores in men, citing previous studies finding silicon has greater bioavailability as a liquid. It is less clear why liquor and wine might protect BMD.. (Newsmax)
Scientist: Tests show turf fields are safe Feb 12, 2009
I m quite confident, both because the total lead content is very low and the bioavailability [of lead within the plastic blades of grass] is unmeasurable. Green told the selectmen that she and her colleagues have spent 30 years looking at how the land children play on affects them. (Concord Journal, MA)
Merrion Completes Patient Enrolment in Phase IIb Study -- Results Will be Announced in Q2 2009 Feb 10, 2009
Merrion's patented drug delivery technologies increase bioavailability, by improving absorption in the gastrointestinal tract, of drugs that are otherwise poorly absorbed. This can provide substantial benefit in patient convenience and safety, and might also provide enhanced drug efficacy. (Primezone Releases)
Gods gift or federal offense? Feb 8, 2009
The oral, synthetic THC has low and variable bioavailability. Oral THC is slow in onset of action but produces more pronounced, and often unfavorable, psychoactive effects that last much longer than those experienced with smoking. (Montrose Daily Press, CO)
