Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells Aug 30, 2009
Our data show that stimulation of cellular lipid biosynthesis by amphiphilic psychotropic drugs is followed by a transcriptional activation of cholesterol transport and efflux pathways. Such effects may be relevant for both therapeutic effects and metabolic adverse effects of psychotropic drugs. (BioMed Central)
Nanotechnology Combats Fatal Brain Infections Jun 30, 2009
On a nanoscale, IBN's antimicrobial peptide nanoparticle is a new type of nanoparticle that is self-assembled from an amphiphilic oligopeptide, which contains a component that promotes cell penetration on its surface. Blood Brain Barrier. (Science Daily)
Singapore nanotechnology combats fatal brain infections Jun 29, 2009
On a nanoscale, IBN's antimicrobial peptide nanoparticle is a new type of nanoparticle that is self-assembled from an amphiphilic oligopeptide, which contains a component that promotes cell penetration on its surface. BLOOD BRAIN BARRIER: The blood brain barrier refers to the brain's covering membrane, which is a layer of endothelial cells that are held together firmly by tight junctions. (EurekAlert!)
* Research group sets up biopharma firm May 14, 2009
ADT's principal aim is to promote self-assembled amphiphilic nanocapsules and drug-loading nanoparticle delivery systems, Liu said. In the team's study, a magnetic-sensitive microcapsule was prepared using a polyelectrolyte to construct the shell, he said. (Taipei Times, Taiwan -- Business)
Zinc Oxide Gives Green Shine To New Photoconductors Mar 28, 2009
9, 2009) Researchers have produced amphiphilic hybrid particles made of a water-insoluble inorganic nanoparticle at the core surrounded by a bristle-like layer of hydrophilic polymer chains. The. (Science Daily)
Nanotechnology: Bristly Spheres As Capsules for Drugs Mar 10, 2009
9, 2009) Amphiphilic molecules, which have one water-friendly (hydrophilic) end and one water-repellant (hydrophobic) end, spontaneously aggregate in aqueous solutions to make superstructures like capsules or bilayers ... rster have now produced amphiphilic hybrid particles made of a water-insoluble inorganic nanoparticle at the core surrounded by a bristle-like layer of hydrophilic polymer chains ... Micelle and Vesicle Formation of Amphiphilic Nanoparticles. (Science Daily)
Bristly spheres as capsules Mar 7, 2009
Nanoparticle brushes: Complex nanostructures can be formed by self assembly of amphiphilic CdSe/CdS core-shell nanoparticles that bear a brushlike layer of poly(ethylene oxide) chains ... Amphiphilic molecules, which have one water-friendly (hydrophilic) end and one water-repellant (hydrophobic) end, spontaneously aggregate in aqueous solutions to make superstructures like capsules or bilayers ... As reported in the journal Angewandte Chemie, researchers at the Universities of Hamburg and... (EurekAlert!)
