Scientists ID a Protein That Splices and Dices Genes Feb 5, 2010
D., a professor in the Department of Cellular and Structural Biology and the Sam and Ann Barshop Institute for Longevity and Aging Studies at the UT Health Science Center San Antonio, has studied the function of MRG15 for more than 10 years ... Dr. Tominaga, a faculty member of the Department of Cellular and Structural Biology and the Barshop Institute in San Antonio, said it may be possible to design cancer drugs to regulate MRG15's activity. (Science Daily)
Insulin Research Points Way to Better Diabetes Treatments Feb 1, 2010
By developing and analysing a range of super active insulins, scientists from the York Structural Biology Laboratory at the University of York have been able to identify common features that point to the likely molecular structure of human insulin when it is active in the body ... Dr Marek Brzozowski, from the York Structural Biology Laboratory, said: "The structures of inactive forms of insulin and the insulin receptor are reasonably well known, but documenting how they interact has proven to... (Science Daily)
Proteins' Dynamic Motion Important in Body's Immune Response Jan 29, 2010
28, 2010) A discovery by associate professor of chemistry and biochemistry Brian Baker and his research group at the University of Notre Dame reveals the importance of dynamic motion by proteins involved in the body's immune response. Results of the study were published in Immunity, the leading research journal in the field of immunology. (Science Daily)
Chaperonins Prompt Proper Protein Folding -- But How? Jan 25, 2010
Funding for this work came from the National Institutes of Health Nanomedicine Development Center Roadmap Initiative, the Biomedical Technology Research Center for Structural Biology in the National Center for Research Resources, a Nanobiology Training Fellowship administered by the Keck Center of the Gulf Coast Consortia and the National Science Foundation. Email or share this story. (Science Daily)
Notre Dame study focuses on protein dynamics Jan 22, 2010
" The static view long-favored in structural biology is shifting to a greater emphasis on protein dynamics, he says. For example, scientists have discovered that vaccines can help the immune system fight cancer, but vaccines that mimic biological structures can still fail if they do not take into account flexibility and dynamics. "It probably will be one of the defining areas of biochemistry over the next 10 to 15 years getting at the role of how biological molecules move and how that movement... (EurekAlert!)
Researcher Discovers Ebola's Deadly Secret Jan 21, 2010
and the Advanced Photon Source Structural Biology Center Sector 19 beamlines. Email or share this story. (Science Daily)
Rules Governing RNA's Anatomy Revealed Jan 10, 2010
A major goal in structural biology and biophysics is to be able to predict not only the complex three-dimensional shapes that RNA assumes (which are dictated by the order of its nucleic acid building blocks), but also the various shapes RNA takes on after binding to other molecules such as proteins and small-molecule drugs. Further, researchers would like to be able to manipulate the 3-D structure and resulting activity of RNA by tweaking the drug molecules with which it interacts. (Science Daily)
Methods and Protocols Jan 10, 2010
Visit the new, free PSI-Nature Structural Genomics Knowledgebase (PSI-SGKB), which makes available the research data and tools from the Protein Structure Initiative, complemented with structural biology updates from NPG.. to visit the PSI-SGKB.. (Nature News Service)
authors & referees @ NPG Jan 10, 2010
Nature Structural & Molecular Biology evolved from the successful Nature Structural Biology. It publishes studies that advance the understanding of molecular mechanisms underlying all cellular processes, and that provide mechanistic insights. (Nature News Service)
Nature Reviews Drug Discovery Jan 10, 2010
The site makes available the research data and tools from the Protein Structure Initiative, complemented with structural biology updates from NPG. Users can also suggest proteins for structure analysis. A selection of conferences in the field of drug discovery and development. (Nature News Service)
