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    News and Articles on Computational Biology

    Archives: Computational Biology

    Australia's new supercomputer outflops the lot  Nov 17, 2009
    " All those flops certainly require a lot of power with the Vayu sucking more than 600 kilowatts of power every moment it's switched on. That's roughly equivalent to 140 electric ovens running permanently, though Professor Botten says all power for the hungry machine will be sourced from green energy. The CSIRO and the ANU each paid more than $3 million, for which they get about a quarter of the machine. In keeping with the green theme, one of the Vayu's main uses will be helping to model... (Sydney Morning Herald -- Technology)

    Leishmaniasis: New Strategy To Find Drugs To Treat Neglected Parasitic Infection  Nov 11, 2009
    D., Department of Computational Biology, Pitt School of Medicine; and Capt. Jacob Johnson, Ph. D., Lt. Col. Michael O'Neil, Ph. (Science Daily)

    Synthetic Molecules Boost Immune Response  Nov 6, 2009
    The study, in PLoS Computational Biology, incorporates detailed interactions between a mutating virus and the immune. (Jan. (Science Daily)

    Mimicking Nature, Scientists Can Now Extend Redox Potentials  Nov 6, 2009
    Lu is affiliated with the university's Beckman Institute, the departments of biochemistry, bioengineering, and materials science and engineering, the Frederick Seitz Materials Research Laboratory, and the Center of Biophysics and Computational Biology. The National Science Foundation and the National Institutes of Health funded the work. (Science Daily)

    Hydrogen Peroxide May Tell Time For Cells  Nov 4, 2009
    "H2O2 might be functioning as a systemic signal by which rhythms are regulated within cells and between cells," said lead author John Tower, associate professor in molecular and computational biology at USC College ... Simon Tavare, professor of mathematics and molecular and computational biology at USC College, designed and supervised the statistical analyses. (Science Daily)

    WCMC-Q biomedical research program builds scientific knowledge, technical workforce in Qatar  Nov 3, 2009
    Plus initiation of core capabilities in research laboratories, including the genomics and proteomics cores, computational biology and biostatistics core, a vivarium, a microscopy core, and a basic laboratory support core. Focus. (EurekAlert! -- Business News)

    HIV Tamed By Designer 'Leash'  Oct 30, 2009
    HIV Tamed By Designer 'Leash. HIV Tamed By Designer 'Leash. (Science Daily)

    Scientists Use World's Fastest Supercomputer To Create The Largest HIV Evolutionary Tree  Oct 29, 2009
    28, 2009) Supporting Los Alamos National Laboratory's role in the international Center for HIV/AIDS Vaccine Immunology (CHAVI) consortium, researchers are using the Roadrunner supercomputer to analyze vast quantities of genetic sequences from HIV infected people in the hope of zeroing in on possible vaccine target areas. Physicist Tanmoy Bhattacharya and HIV researcher Bette Korber have used samples taken by CHAVI across the globe -- from both chronic and acute HIV patients -- and created an... (Science Daily)

    How Low Doses Of Radiation Can Cause Heart Disease And Stroke  Oct 24, 2009
    Results, published October 23 in the open-access journal PLoS Computational Biology, are consistent with risk levels reported in previous studies involving nuclear workers ... PLoS Computational Biology, 2009; 5 (10): e1000539 DOI. (Science Daily)

    Low dose radiation 'harms heart'  Oct 23, 2009
    The team at Imperial College, writing in the journal PLOS Computational Biology, say they explored a novel mechanism that suggests radiation kills monocytes, which travel across the arterial wall to mop up a protein called MCP-1. More research like this is needed if the results of epidemiological studies are to be properly understood, but there is still some way to go before it may be reliably concluded that low-level radiation can increase the risk of circulatory disease. (BBC News -- Health)

    Ga. Tech gets $12M grant for high-speed computing  Oct 22, 2009
    The new computers will used by scientists to widen the range of research projects they can handle for subjects like computational biology, combustion and engineering. The program will also concentrate on conducting workshops and training to help attract young students, women and minorities to careers in high-performance computing. (Atlanta Journal-Constitution -- Metro)

    No Such Thing As 'Junk RNA,' Say Researchers  Oct 19, 2009
    D., assistant professor, Department of Computational Biology, Pitt School of Medicine ... D., Yuefeng Lin, of the Department of Computational Biology; Patrick S. Moore, M.D., M.P.H, Department of Microbiology and Molecular Genetics and the Molecular Virology Program, UPCI; and Yuan Chang, M.D., Molecular Virology Program, UPCI.. (Science Daily)

    UM School of Medicine researchers find extreme genetic variability in malaria parasite  Oct 15, 2009
    D., assistant professor of medicine at the University of Maryland School of Medicine and a research scientist in the CVD. The study was conducted in collaboration with researchers at the University of Bamako in Mali, West Africa, and at the Center for Bioinformatics and Computational Biology and Department of Biology at the University of Maryland, College Park ... "Applying a molecular evolutionary perspective to the study of the malaria parasite gave us new information about why it has been so... (EurekAlert!)

    M.D. Anderson receives $8.3M grant  Oct 9, 2009
    John Weinstein, chairman of the department of bioinformatics and computational biology; Prof. Gordon Mills, chairman of the department of systems biology; and Prof. (Houston Business Journal, TX)

    Cardiac-Resynchronization Therapy for the Prevention of Heart-Failure Events  Oct 1, 2009
    From the Departments of Medicine (A.J.M., H.K., M.W.B., W.Z.) and Biostatistics and Computational Biology (W.J.H.), University of Rochester Medical Center, Rochester, NY; Division of Cardiology, Hospital of the Good Samaritan, Los Angeles (D.S.C.); the Department of Medicine, Duke University Medical Center, Durham, NC (J.P.D.); New England Cardiac Arrhythmia Center, Tufts New England Medical Center, Boston (N.A.M.E.); Cardiology Unit, University of California at San Francisco, San Francisco... (New England Journal of Medicine)

    Stimulus-funded university research addressing issues from climate change to cancer, creating jobs and training a new generation of scientists  Sep 30, 2009
    Hawkins is working in the lab of Susan Forsburg, a professor of molecular and computational biology at USC College. He and two graduate students are studying the genetic roots of miscarriages by exploring related genes in the model organism S. pombe, a type of yeast. (EurekAlert! -- Business News)

    Duke-National University of Singapore Graduate Medical School opens new home  Sep 30, 2009
    The state-of-the-art facility features research laboratories, teaching and education spaces, genomic and computational biology research centers and a library. "The new Khoo Teck Puat Building provides faculty and students with a world-class environment in which to achieve our missions of advancing innovative medical education, creating a new generation of clinician-scientists, and speeding the translation of scientific discoveries to the bedside and thereby closing the gaps in healthcare... (Raleigh Triangle Business Journal, NC)

    More News »  Sep 24, 2009
    The University's first vice president for research says he hopes to raise the University's research profile by starting new research centers in the fields of autism, computational biology, science policy, energy, sustainability and neglected diseases. by Amy D'OnofrioAssistant News Editor. (GW Hatchet, Washington DC)

    Official plans new research centers  Sep 24, 2009
    The University's first vice president for research says he hopes to raise the University's research profile by starting new research centers in the fields of autism, computational biology, science policy, energy, sustainability and neglected diseases. Vice President for Research Dr. Leo Chalupa, who started at GW last April, said he has created committees of faculty members from departments across the University to assess the feasibility of at least two of these new research centers, and hopes... (GW Hatchet, Washington DC)

    Staff Editorial: Raising the bar for research  Sep 24, 2009
    Dr. Chalupa hopes to start new research in the fields of computational biology, autism, science policy, energy, sustainability and neglected diseases. Starting at GW last April, he has lost little time in identifying the areas of study that will raise GW's profile and hold promise as fields of growing interest in the coming years. (GW Hatchet, Washington DC)

    How Xbox Can Help Fight Heart Disease  Sep 24, 2009
    The system, detailed in a study in the August edition of the Journal of Computational Biology and Chemistry, is based on a video-game demo created by Simon Scarle two years ago when he was a software engineer at Microsoft's Rare studio, the division of the U.S.-based company that designs games for the Xbox 360. Scarle modified a chip in the console so that instead of producing graphics for the game, it now delivers data tracking how electrical signals in the heart move around damaged cardiac... (Time.com)

    Bill Gates dedicates building at CMU  Sep 23, 2009
    The four-story Hillman Center is 60,000 square feet, and houses the Lane Center for Computational Biology, the Language Technologies Institute, and the Rashid Auditorium, a lecture hall named for former CMU faculty member Rick Rashid, who is now Microsoft's senior vice president for research. Most Read Stories. (Puget Sound Business Journal, WA)

    Bill Gates dedicates building at Carnegie Mellon University  Sep 23, 2009
    The four-story Hillman Center is 60,000 square feet, and houses the Lane Center for Computational Biology, the Language Technologies Institute, and the Rashid Auditorium, a lecture hall named for former CMU faculty member Rick Rashid, who is now Microsoft's senior vice president for research. Security was tight around the Tuesday afternoon event, with both city and campus police guarding entrances to the Wiegand Gymnasium, where the ceremonies were held. (Pittsburgh Business Times, PA)

    Mechanism Related To Onset Of Various Genetic Diseases Revealed  Sep 21, 2009
    Researchers believe this discovery, published recently in the journal PLoS Computational Biology, could also be the cause of other diseases of unknown origins ... PLoS Computational Biology, 2009; 5 (8): e1000476 DOI. (Science Daily)

    HIV Uses Several Strategies To Escape Immune Pressure  Sep 21, 2009
    The study, in PLoS Computational Biology, incorporates detailed interactions between a mutating virus and the immune. (July 8, 2007) A pioneering collaborative study has discovered how the HIV virus evades the human body's immune system. (Science Daily)

    Researchers Using Parallel Processing Computing Could Save Thousands By Using An Xbox  Sep 16, 2009
    The results of his work have just been published in the journal Computational Biology and Chemistry ... Computational Biology and Chemistry, 2009; 33 (4): 253 DOI. (Science Daily)

    Qatar home to world-class biomedical research program  Sep 16, 2009
    "We have already embarked on two proof of concept research projects. The first one compares variations in gene expression levels in the airways of smokers and non-smokers, whereas the second one assesses the clinical care of diabetes and cardiovascular illnesses in Qatar. In addition, we have initiated the process of developing core capabilities in our research laboratories, including the genomics and proteomics cores, computational biology and biostatistics core, a vivarium, a microscopy core,... (EurekAlert! -- Business News)

    Xbox speeds up research results  Sep 15, 2009
    Page last updated at 11:13 GMT, Monday, 14 September 2009 12:13 UK. Part of Dr Scarle's research was done on an Xbox 360. (BBC News -- Technology)

    Google trick tracks extinctions  Sep 5, 2009
    According to a paper in PLoS Computational Biology, "PageRank" can be applied to the study of food webs ... They also tested algorithms already in use in computational biology to find a solution to the same problem. (BBC News)

    Web Page Ranking Algorithm Detects Critical Species In Ecosystems  Sep 5, 2009
    Details are published September 4 in the open-access journal PLoS Computational Biology ... PLoS Computational Biology, 2009; 5 (9): e1000494 DOI. (Science Daily)

    Computational Process Zeroes In On Top Genetic Cancer Suspects  Sep 3, 2009
    8, 2008) A team of US, Israeli and German scientists used computational biology techniques to discover 480 genes that play a role in human cell division and to identify more than 100 of those genes that have. (May 19, 2009) A new tool will help researchers identify the minute changes in DNA patterns that lead to cancer, Huntington's disease and a host of other genetic disorders. (Science Daily)

    Milk Drinking Started Around 7,500 Years Ago In Central Europe  Sep 2, 2009
    1, 2009) The ability to digest the milk sugar lactose first evolved in dairy farming communities in central Europe, not in more northern groups as was previously thought, finds a new study led by UCL (University College London) scientists published in the journal PLoS Computational Biology. See also. (Science Daily)

    At Singularity U., Brains Meet the Future  Aug 21, 2009
    So she pointed out how she had never before thought about how someone working in quantum computing might have their research converge with health care, or how fields like computational biology, quantum computing and protein folding intersect. The results of such convergence down the line. (CBS News)

    The ordering of expression among a few genes can provide simple cancer biomarkers and signal BRCA1 mutations  Aug 21, 2009
    A major challenge in computational biology is to extract knowledge about the genetic nature of disease from high-throughput data. However, an important obstacle to both biological understanding and clinical applications is the "black box" nature of the decision rules provided by most machine learning approaches, which usually involve many genes combined in a highly complex fashion. (BioMed Central)

    Pitt scientists find intrinsic changes in protein shape influence drug binding  Aug 20, 2009
    D., professor and John K. Vries Chair of the Department of Computational Biology, Pitt School of Medicine. But it now appears that a protein has many different conformations that are already available even without the presence of a binding molecule, which is called the ligand. (EurekAlert!)

    NIH's new chief vows to lead agency 'as a scientist'  Aug 18, 2009
    Exploding research areas such as nanotechnology, genetics and computational biology. Efforts to turn research discoveries into new medications, usually financed by pharmaceutical firms. (USA Today)

    How Computers Learn To Listen: Scientists Develop Model To Improve Computer Language Recognition  Aug 17, 2009
    (PLoS Computational Biology, August 12th, 2009) ... PLoS Computational Biology, 2009; DOI. (Science Daily)

    Math model accurately mimics cell division in carbon-cycling bacterium  Aug 14, 2009
    C. crescentus, an alpha-proteobacterium that inhabits freshwater, seawater and soils, is an ideal organism for genetic and computational biology studies due to the wealth of molecular information that has been accumulated by researchers ... The researchers work will appear in the August 14 edition of PLoS Computational Biology ... The article "Temporal controls of the asymmetric cell division cycle in Caulobacter crescentus" is by Genetics, Bioinformatics, and Computational Biology graduate... (EurekAlert!)

    New Computer Simulation Helps Explain Folding In Important Cellular Protein  Aug 11, 2009
    st, formerly of UGA and now employed in Switzerland; Landau, and Ying Xu, Regents-Georgia Research Alliance Eminent Scholar and professor of bioinformatics and computational biology, also at UGA. Landau and Xu are in UGA s Franklin College of Arts and Sciences. This work demonstrates the power and potential of combining expertise from computational physics and computational biology in solving challenging biological problems, said Xu. (Science Daily)

    Innovative Method To Detect Genetic Causes Of Complex Diseases Identified  Aug 10, 2009
    Xing, a member of the Ray and Stephanie Lane Center for Computational Biology at Carnegie Mellon, is working with colleagues at the University of Pittsburgh School of Medicine and Harvard Medical School to use GFlasso to study severe asthma as part of an ongoing study sponsored by the National Institutes of Health. This research was supported by the National Science Foundation, the National Institutes of Health and the Alfred P. Sloan Foundation. (Science Daily)

    African village dogs are genetically much more diverse than modern breeds  Aug 5, 2009
    "The genes of modern breeds all cluster together in one little group, but the African village dogs we sampled show much greater diversity genetically," said lead author Adam Boyko, a research associate in the lab of Carlos Bustamante, the paper's senior author and a professor of biological statistics and computational biology. Field researchers from the University of California-Davis, who are part of the Cornell-based Village Dog Genetic Diversity Project, and others, including local... (EurekAlert!)

    Dog domestication likely started in N. Africa  Aug 4, 2009
    Boyko, a research associate in the Department of Biological Statistics and Computational Biology at Cornell University, and his colleagues looked at three genetic markers for 318 village dogs from seven regions in Egypt, Uganda and Namibia. The scientists performed the same on a number of putatively African dog breeds, as well as on Puerto Rican street dogs and mixed breed dogs from the United States. (MSNBC -- Technology)

    Domestic dog origins challenged  Aug 4, 2009
    Lead scientist, Dr Adam Boyko of the Department of Biological Statistics and Computational Biology at Cornell University, says he decided to look at village dogs because they are so much more genetically diverse than bred dogs that they may hold the key to the origins of dog domestication. The team analysed DNA from 318 dogs from villages in Egypt, Uganda and Namibia and measured their genetic diversity. (BBC News)

    W.M. Keck Foundation Awards $1 Million to Hutchinson Center Scholar to Study How Cells Go Awry  Aug 4, 2009
    Shou completed her postdoctoral work in quantitative biology at the Rockefeller University and in computational biology at Memorial Sloan-Ketting Cancer Center. She earned her doctorate from the California Institute of Technology. (PR Newswire)

    Life in the Clouds  Aug 2, 2009
    Aeroecology is a multi-disciplinary science that encompasses and integrates aspects of atmospheric science, earth science, geography, ecology, computer science, computational biology, and engineering. Aeroecologists face three main problems as they attempt to probe the aerosphere. (Suite101.com)

     Local teacher completes MSU tech training  Jul 23, 2009
    Focusing on the emerging fields of computational biology and human physiology modeling, the curriculum was developed by the NSF s Office of Experimental Programs to Stimulate Competitive Research and National Institutes of Health s Human Genome Project, said associate professor Giselle Thibaudeau, the MS-EPSCoR education/outreach coordinator. Teachers from acrosss the state apply (application form, resume, reference letter from principle) and 30 were selected each year, Thibaudeau said. (Forest Scott County Times, MS)

    Scientists decode genome of deadly parasitic worm  Jul 16, 2009
    Najib El-Sayed is an Associate Professor of Cell Biology and Molecular Genetics with a joint appointment in the Center for Bioinformatics and Computational Biology at the University of Maryland Institute for Advanced Computer Studies (UMIACS). He is also affiliated with the Maryland Pathogen Research Institute (MPRI). (EurekAlert!)

    Synchronised light bursts may make jet lag history  Jul 16, 2009
    The method has been described in the open-access journal PLoS Computational Biology. Travelling across several times zones can cause an individual to experience jet lag, which includes trouble sleeping at night and difficulty remaining awake during the day. (India Times, India -- Health/Science)

    On the 40th anniversary of the first manned moon landing today's scientists point to new frontiers  Jul 16, 2009
    D. Phillip H. and Catherine C. Horvitz Professor, Department of Computer Science Director, Center for Bioinformatics and Computational Biology University of Maryland, College Park Dr. Salzberg's research focuses on the development of computational algorithms for analyzing DNA sequencing and is supported by grants from the National Library of Medicine, the National Institute of General Medical Sciences, the National Institute of Allergy and Infectious Diseases, the U.S. Department of Agriculture,... (EurekAlert!)

    New map of genomic variations will enable disease research  Jul 16, 2009
    In addition, the David Lawrence Altschuler Chair in Genomics and Computational Biology at Children's Hospital contributed funds to the study. Co-authors, including co-lead author Xiaowu Gai, represented both Children's Hospital and the University of Pennsylvania School of Medicine. (EurekAlert!)

    Genome-wide Map Shows Precisely Where MicroRNAs Do Their Work  Jul 7, 2009
    The researchers, including first author Sung-Wook Chi, a graduate fellow in the Tri-Institutional Computational Biology Program, Julie Zang, a biomedical fellow, and Aldo Mele, a research assistant, found that on average, about two microRNAs bind to each messenger RNA. They also found that microRNAs bind to nucleotides not only at the terminal end of a messenger RNA, but also at other regions including sequences coding for proteins and sequences once thought to be junk RNA, providing new... (Science Daily)

    Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients  Jul 7, 2009
    According to senior author Naftali Kaminski, M.D., associate professor of medicine, computational biology and pathology, and director of the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases at the University of Pittsburgh School of Medicine and UPMC, the research published today in the American Journal of Respiratory and Critical Care Medicine addresses a dilemma in IPF care that currently is unsolved. "Approximately 10 percent of patients develop an acute phase that in... (EurekAlert!)

    Accelerated Fertility Treatment Leads To Shortened Time To Pregnancy And Cost Savings  Jul 6, 2009
    D., Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts; Peter J. Neumann Sc. D., and Bat-Sheva Levine M.D., Center for the Evaluation of Value and Risk in Health, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts; Kim L. Thornton M.D., and Michael M. Alper M.D., Department of Obstetrics, Gynecology and Reproductive Biology, Division of Reproductive Endocrinology and Infertility, Beth... (Science Daily)

    Existing Parkinson's Disease Drug May Fight Drug-resistant TB  Jul 5, 2009
    The study will be published in the July 3rd issue of the Public Library of Science (PLoS) Computational Biology journal. "We have computational, and experimental data to support this repositioning," said Philip E. Bourne, PhD, professor of pharmacology at UCSD's Skaggs School of Pharmacy and Pharmaceutical Sciences and the principle investigator on the project. (Science Daily)

    Computer Scientists Develop Model For Studying Arrangements Of Tissue Networks By Cell Division  Jul 4, 2009
    The finding, published in the June 2009 issue of PLoS Computational Biology, could lead to insights about how multicellular systems achieve (or fail to achieve) robustness from the seemingly random behavior of groups of cells and provide a roadmap for researchers seeking to artificially emulate complex biological behavior. "We developed a model that allows us to study the topologies of tissues, or how cells connect to each other, and understand how that connectivity network is created through... (Science Daily)

    New e-science service could accelerate cancer research  Jul 2, 2009
    a centralised registry of curated life science Web Services, is being officially launched today (Wednesday 1 July) at the 17th Annual International Conference on Intelligent Systems for Molecular Biology and the 8th European Conference on Computational Biology conference (ISMB-ECCB 2009) in Stockholm. This type of systematic access has the potential to significantly accelerate the work of researchers in the medical, agronomical and pharmaceutical fields. (EurekAlert! -- Business News)

    Novel epigenetic markers of melanoma may herald new treatments for patients  Jun 30, 2009
    The journal also features exciting gene discoveries and reports of cutting-edge computational biology and high-throughput methodologies. About Cold Spring Harbor Laboratory Press. (EurekAlert!)

    European researchers look for new ways to fight multi-drug-resistant bacterial infections  Jun 26, 2009
    Contact researcher: Xavier Daura, ICREA Research Professor Group of Computational Biology and Proteomics Institute of Biotechnology and Biomedicine Universitat Autnoma de Barcelona E-08193 Bellaterra (Barcelona). Phone: (+34)93 581 2805 Fax: (+34)93 581 2011 E-mail. (EurekAlert! -- Business News)

    Algorithm Charts Evolution Of Genetic Networks During Fruit Fly Life Cycle  Jun 25, 2009
    " In a paper to be published online June 22 in the Early Edition of the Proceedings of the National Academy of Sciences, Xing and Amr Ahmed, a Ph.D. student in the Language Technology Institute, detail how the Tesla algorithm can be used to analyze not only evolving gene networks in fruit flies, but also changes in voting alliances in the U.S. Senate and shifts in the social network of the machine learning academic community. "Once we understand the dynamics of a network, we can build models... (Science Daily)

    Natural Computing And Synthetic Biology Techniques Advanced For Treating Diseases  Jun 19, 2009
    One of the synthetic biomolecular circuit designs developed by this group is to be presented at the 3rd International Workshop on Practical Applications of Computational Biology & Bioinformatics (IWPACBB'09) to be held in Salamanca (Spain) this week. The synthetic genetic circuit to be presented at Salamanca outputs a biological signal. (Science Daily)

    Cells Are Like Robust Computational Systems, Scientists Report  Jun 18, 2009
    "Similarities in the sequences of certain master genes allow them to back up each other to a degree we hadn't appreciated," said Bar-Joseph, an assistant professor of computer science and machine learning and a member of Carnegie Mellon's Ray and Stephanie Lane Center for Computational Biology. Between 5 and 10 percent of the genes in all living species are master genes that produce proteins called transcription factors that turn all other genes on or off. (Science Daily)

    Rare disorder gives modelers first glimpse at immune system development  Jun 17, 2009
    D., Division Chief of Computational Biology, tracked three young patients after thymus tissue transplantation to measure the growth of a T cell population with all of its diversity ... "What we haven't understood until now is how maintaining the diversity of T cells with different receptors works while a body also maintains appropriate T cell numbers overall," said Kepler, who is senior author of a paper published in PloS Computational Biology. (EurekAlert!)

    Bats 'recognise others' voices'  Jun 6, 2009
    In the journal PLoS Computational Biology, the scientists report that the bats have an internal "reference" call to which they compare others. Yossi Yovel from the Weizmann Institute of Science, Israel, and his colleagues in Germany recorded the echolocation calls of five greater mouse-eared bats. (BBC News)

    Bats recognize the individual voices of other bats  Jun 5, 2009
    The study, published June 5 in the open-access journal PLoS Computational Biology, explains how bats use echolocation for more than just spatial knowledge ... This press release refers to an upcoming article in PLoS Computational Biology ... About PLoS Computational Biology. (EurekAlert!)

    MedTrust Online Completes Second Round of Financing, Releases Next Generation Search Engine for Oncology Utilizing Dell eHealthcare Architecture Framework  May 31, 2009
    MedTrust Online brings together experts in Oncology, information technology, computational biology, pharmaceutical drug development, and personalized medicine to capture, organize, analyze, integrate and present the most up-to-date medical facts from a vast array of sources. This data is provided to doctors in a comprehensive yet concise way unavailable anywhere else. (PR Newswire)

    Determining Success Or Failure In Cholesterol-controlling Drugs  May 23, 2009
    Their work, published in the May 15 issue of PLoS Computational Biology, uses a novel computational strategy to identify protein-ligand binding profiles on a genome-wide scale. In this case, the strategy was applied to explain the molecular mechanisms associated with adverse drug effects. (Science Daily)

    New 3-D structural model of critical H1N1 protein developed  May 23, 2009
    With the Biology Direct journal paper, the Singapore scientists have become the first to demonstrate how bioinformatics and computational biology can contribute towards managing the H1N1 influenza A virus. "BII's H1N1 virus sequence study marks a significant milestone in the use of computational biology methods in understanding how the mutations of the fast evolving influenza virus affect immunogenic properties or drug response," said BII Director Frank Eisenhaber, Ph. (EurekAlert!)

    Influenza Virus Evades Body's Immune Response Through Newly Discovered Mechanism  May 22, 2009
    ScienceDaily (May 21, 2009) Researchers at the University of Southern California (USC) have identified a critical molecular mechanism that allows the influenza virus to evade the body's immune response system. "We have found a mechanism that the influenza virus uses to inhibit the body's immune response that emphasizes the vital role of a certain protein in defending against viruses,"," says Jae Jung, Ph.D., professor and chair of the Department of Molecular Microbiology and Immunology at the... (Science Daily)

    Xilinx & BEEcube to Unveil Next-Generation FPGA-based Multi-core SoC Development Platform for Sun OpenSPARC  May 22, 2009
    Applications of BEEcube solutions include MIMO wireless communications, video signal processing, multi-core system-on-chip development, and computational biology. The latest BEE3 system solutions have been deployed worldwide in US, Canada, UK, Germany, Spain, Japan, and China. (PR Newswire)

    Computer Simulation Captures Immune Response To Flu  May 21, 2009
    D., principal investigator of the project, director of the Center for Biodefense Immune Modeling (CBIM) and division chief of the Department of Biostatistics and Computational Biology, and by Martin S. Zand, M.D., Ph ... Along with Wu and Zand, major project contributors included Ha Youn Lee, Sung Yong Park, Jeanne Holden-Wiltse and Hongyu Miao in the Department of Biostatistics and Computational Biology at the Medical Center; David Topham, Joseph Hollenbaugh, Tim Mosmann and Brian Ward within... (Science Daily)

    New Tool Helps Researchers Identify DNA Patterns Of Cancer, Genetic Disorders  May 20, 2009
    Cox will present the research this July at BIOCOMP '09 The 2009 International Conference on Bioinformatics and Computational Biology in Las Vegas. The research was co-authored by Dr. Lina Dagnino of the University of Western Ontario. (Science Daily)

    Child brains wired differently than adult ones  May 19, 2009
    The researchers are now examining ways to adapt the study, detailed online in the journal PLoS Computational Biology, to the changing physical geography of younger brains. The research was supported by funding from the National Institutes of Health, National Science Foundation, John Merck Scholars Fund, Burroughs-Wellcome Fund, Dana Foundation, Ogle Family Fund, Washington University Chancellor's Graduate Fellowship and UNCF/Merck Graduate and Postgraduate and Science Research Fellowship. (MSNBC -- Health)

    Genome-wide Insights Into Patterns Of The World's Human Population Structures  May 19, 2009
    Funding from the National Institutes of Health, a Sloan Research Fellowship in Computational Biology, and a National Human Genome Research Institute Interdisciplinary Training in Genomic Sciences grant supported this Akey laboratory research project. Adapted from materials provided by. (Science Daily)

    Study finds genetic links to age of first menstrual period and menopause  May 18, 2009
    Daniel Chasman, Director of Computational Biology in the Center for Cardiovascular Disease Prevention at BWH, said: "The collaboration of the WGHS and the NHS represents a great example of how large cohorts with genome-wide data can complement each other. While only one locus reached near genome-wide significance in the NHS alone, the meta-analysis of combined data had much more statistical power and revealed a total of two loci for timing of menarche and four for timing of menopause." Chasman,... (EurekAlert!)

    Scientist to Watch: Dennis Wall  May 12, 2009
    In 2003, Wall became the director of Harvard Medical School's Computational Biology Initiative. There he created an online content management system that integrated tools used by many HMS researchers to analyze DNA and amino acid sequences. (The Scientist)

    Spontaneous Activity Found In The Idling Brain  May 9, 2009
    The researchers' latest findings are published in the journal PLoS Computational Biology ... PLoS Computational Biology, 2009; DOI. (Science Daily)

    OHSU researchers study the idling brain  May 8, 2009
    The researchers' latest findings are published in the journal the Public Library of Science Computational Biology. "For years, the vast majority of scientists studying human functional brain organization have focused on how activity changes when engaged in specific tasks," explained Damien Fair, Ph. (EurekAlert!)

    Experts say mild swine flu could quickly turn deadly  May 6, 2009
    Flu reproduces about every eight hours, said Dr. Raul Rabadan, professor of computational biology at Columbia University. That means this morning's flu is a parent by the afternoon, a grandparent by the evening, and a great-grandparent by the next day. (Honolulu Advertiser)

    Breast health center gives TGen new research opportunities  May 6, 2009
    We're not just here to give the diagnosis, we're here to help patients at all stages," said Gage, a Registered Radiologic Technologist. Breast cancer patients at the new center who agree to donate their tumor tissues will boost TGen's abilities to use genomic and proteomic research toward development of new ways to combat breast cancer. TGen's role at the new center will be for research; not for TGen clinical trials. "We are thrilled that JCL and TGen have developed a strong strategic... (EurekAlert! -- Business News)

    Researchers race to outmaneuver swine flu virus  May 5, 2009
    On Friday, for example, researchers led by Raul Rabadan of the Center for Computational Biology and Bioinformatics at Columbia University published an analysis in the journal Eurosurveillance confirming that the virus was truly a swine flu, with most of its genetic material derived from an infection seen in North American pigs and the rest from Asian ones. "The sequence data coming out so quickly has been spectacular," Racaniello says. (USA Today)

    The Story Of X: Evolution Of A Sex Chromosome  Apr 28, 2009
    The research was funded by the National Institutes of Health, an Alfred P. Sloan Faculty Research Fellowship in Molecular and Computational Biology and a David and Lucile Packard Foundation Fellowship. Journal reference. (Science Daily)

    Autopilot Guides Proteins In Brain  Apr 28, 2009
    The co-authors on the study were first author Tommy Lewis, a graduate student in the molecular and computational biology graduate program at USC, as well as Tianyi Mao and Karel Svoboda from the Howard Hughes Medical Institute at the Janelia Farm Research Campus. The National Institutes of Health and the Howard Hughes Medical Institute funded the research. (Science Daily)

    Computational Biology Illuminates How Cells Change Gears  Apr 28, 2009
    27, 2009) Bioinformatics researchers from UC San Diego just moved closer to unlocking the mystery of how human cells switch from "proliferation mode" to "specialization mode." This computational biology work from the Jacobs School of Engineering's bioengineering department could lead to new ideas for curbing unwanted cell proliferation including some cancers. See also. (Science Daily)

    Researchers study signaling networks that set up genetic code  Apr 15, 2009
    Luthey-Schulten is affiliated with the U. of I.'s Beckman Institute, Center for Biophysics and Computational Biology, and Institute for Genomic Biology. The National Science Foundation funded this work. (EurekAlert!)

    Oxycodone Effective Against Shingles Pain  Apr 8, 2009
    In addition to Dworkin, other authors include, from Rochester, Richard Barbano, Karl Kieburtz and Cornelia Kamp of Neurology; Robert Betts of Medicine; Janet Pennella-Vaughan of Anesthesiology; and Michael McDermott and Carrie Irvine of the Department of Biostatistics and Computational Biology. Other authors include Stephen Tyring of University of Texas Health Science Center; Gary Bennett of McGill University; Erhan Berber of Novartis Pharmaceuticals; John Gnann of the University of Alabama at... (Science Daily)

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