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    News and Articles on Cell Biology

    Archives: Cell Biology

    Maize Cell Wall Genes Identified, Giving Boost to Biofuel Research  Nov 21, 2009
    The Purdue scientists, led by Nicholas Carpita, a professor of plant cell biology, published their findings on the 750 cell wall genes in the journal Plant Physiology on Thursday (Nov. 19). (Science Daily)

    Stem Cells Can Be Used as Skin Grafts  Nov 21, 2009
    In a comment accompanying the article, Holger Schluter, PhD, and Pritinder Kaur, PhD, of the Epithelial Stem Cell Biology Laboratory in Melbourne, Australia, say the latest study "takes research into regenerative skin stem cells to the next level" and "suggests" that cells made from human embryonic stem cells could be transplanted onto burn patients who are awaiting the growth of their own cells. By Bill Hendrick Reviewed by Louise Chang2005-2008 WebMD, LLC. All rights reserved. (CBS News)

    How Crops Survive Drought  Nov 19, 2009
    "I believe Sean's discovery is the most significant finding in plant biology this year and will have profound effects on agriculture worldwide," said Natasha Raikhel, the director of UC Riverside's Center for Plant Cell Biology, of which Cutler is a member ... "This intense interest by the scientific community will certainly accelerate the development of new agrichemicals that can be used to control stress responses in crops, and I believe we need to work openly to tackle problems of such great... (Science Daily)

    UCR plant scientist's research spawns new discoveries showing how crops survive drought  Nov 19, 2009
    "This intense interest by the scientific community will certainly accelerate the development of new agrichemicals that can be used to control stress responses in crops, and I believe we need to work openly to tackle problems of such great importance," said Cutler, an assistant professor of plant cell biology in the ... The research, led by , a professor of plant cell biology at UCR, fleshes out the domino pathway from the receptor down to the proteins that control plant growth. (EurekAlert!)

    Chromosomes dance and pair up on the nuclear membrane  Nov 14, 2009
    "Errors during meiosis lead to age-related human infertility, and to birth defects such as Down syndrome and Klinefelter syndrome," said Abby Dernburg, UC Berkeley associate professor of molecular and cell biology and a Howard Hughes Medical Institute investigator. "Our work teaches us about the fundamental mechanisms of genome organization, about how cells execute processes in precise ways, monitor their own mistakes and correct or eliminate them.". (EurekAlert!)

    Researchers 'Notch' A Victory Toward New Kind Of Cancer Drug  Nov 13, 2009
    "Our work brings us a step closer toward that goal for a protein with major roles in cancer, cardiovascular disease and stem cell biology.". If human physiology is like a puppet show, then transcription factors pull the puppet strings. (Science Daily)

    Stem Cells Restore Cognitive Abilities Impaired By Brain Tumor Treatment  Nov 11, 2009
    The UCI researchers are from the departments of radiation oncology, biological chemistry, and developmental & cell biology; the Institute for Memory Impairments and Neurological Disorders, or UCI MIND; and the Sue & Bill Gross Stem Cell Research Center. The study was supported by grants from the California Institute for Regenerative Medicine and the National Institutes of Health. (Science Daily)

    Some Malignant Tumors Can Be Shut Down After All  Nov 11, 2009
    "This means that we now have a way of attacking cancers that have damaged p53, which are very difficult to treat in the clinic." The study, funded by a Research Scholar Award from the American Cancer Society, appears online ahead of print on November 8th in Nature Cell Biology ... Nature Cell Biology, 2009; DOI. (Science Daily)

    Iowa State University researcher discovers key to vital DNA, protein interaction  Nov 11, 2009
    Researchers in Germany, at Kansas State University, Manhattan; and here at Iowa State (Bing Yang, assistant professor in genetics development and cell biology) had previously shown that these proteins bind host DNA and activate genes important for disease, or in some cases defense against the bacteria. But no one yet understood how different TAL effectors recognized different parts of the DNA in order to attach and turn on the different genes at those locations. (EurekAlert!)

    Brown fat cells provide hope for obesity research  Nov 9, 2009
    National researchers in cell biology have identified proteins that turn normal skin cells into brown fat cells, which use energy to generate heat. Energy only gets burned when your heart beats or your muscles walk up a flight of stairs or when you breathe, said Clay Semenkovich, chief of the division of endocrinology, metabolism and lipid research at the Washington University School of Medicine. (Washington University Student Life, MO)

    * Far from a lab? Turn a cellphone into a microscope  Nov 8, 2009
    Ozcans devices provide a simple solution to a complex problem, said Ahmet Yildiz, an assistant professor of physics and molecular cell biology at the University of California, Berkeley. This is an inexpensive way to eliminate a microscope and sample biological images with a basic cellphone camera instead, he said. (Taipei Times, Taiwan -- Sports)

    Researchers team up for stem cell work  Nov 6, 2009
    In addition, a unique venture at Stanford links biochemistry professor Mark Krasnow with Irving Weissman, director of Stanford's Institute for Stem Cell Biology and Regenerative Medicine, to study progenitor cells in blood and lung tissue for possible future therapies ... The research teams are being linked by the federal heart and blood institute into a Progenitor Cell Biology Consortium and the scientists have already met in the first of a series of sessions over the next seven years to... (San Francisco Chronicle -- Science)

    Evolution of man - Singapore joins first steps of gene study  Nov 5, 2009
    " onclick="Next();" src="/images/butt_next. Aside from being able to compare animal and human genomes, scientists will also be able to understand the genetic changes and adaptions that that occur in vertebrates. (Channelnewsasia.com)

    Singapore scientists join international study of 10,000 vertebrates' genomes  Nov 5, 2009
    "The most challenging intellectual problem in biology for this century will be the reconstruction of our biological past so we can understand how complex organisms such as ourselves evolved," said Nobel Laureate Sydney Brenner, M.D., who co-heads Singapore's Institute of Molecular and Cell Biology (IMCB) comparative genomics laboratory, which will participate in The Genome 10 K Project ... D. Institute of Molecular and Cell Biology, A*STAR Tel: (65) 6586 9571 Email ... Institute of Molecular and... (EurekAlert!)

    Spinal Cord Regeneration: Scar-degrading Enzyme  Nov 5, 2009
    To thermostabilize the enzymes, Bellamkonda, Emory University cell biology associate professor Robert McKeon and Georgia Tech graduate student Hyun-Jung Lee mixed the enzyme with the sugar trehalose. The result -- the enzyme's activity was stabilized at internal body temperature for up to four weeks during in vitro tests. (Science Daily)

    ‘Genes & Jazz’ at Museum of Science  Nov 4, 2009
    We would have paid more attention in science class if the teacher had explained cell biology with jazz music. Harold Varmus has said that Cells are like tiny orchestras, and they contain several instruments. (Boston Globe)

    Stanford, Gladstone grab stem cell funds  Nov 3, 2009
    The Gladstone-Stanford work is funded by the National Heart, Lung and Blood Institute as part of its Progenitor Cell Biology Consortium, which aims to bring together researchers working on heart, lung, blood and technology programs. There are 17 multidisciplinary teams working in nine research hubs, coordinated and administered out of the University of Maryland-Baltimore. (San Jose Business Journal, CA)

    New chief information officer selected  Nov 2, 2009
    A CIO search committee, chaired by Debra Kendall, UConn professor of Molecular and Cell Biology, was created to help screen and determine final candidates for the CIO position. Gilbertson applied for the position and has been communicating with the search committee since June. (The Daily Campus, CT)

    Michigan panel debates stem cell research bills  Oct 30, 2009
    "These bills would impede the development of the life sciences sector in Michigan by making it illegal to pursue mainstream forms of medical research that are widely accepted throughout the rest of the country," said Sean J. Morrison, director of the Center for Stem Cell Biology. But some lawmakers defended the Legislature's right to detail and enact the broad amendment voted into the constitution. (Ionia Sentinel-Standard, MI)

    Stem cell agency awards $230 million in grants  Oct 30, 2009
    "There is a very serious shortage for all stem cell research," said Dr. Irving Weissman, director of Stanford University's Institute for Stem Cell Biology and Regenerative Medicine. The state agency "allows us to do research that the federal government won't fund.". (San Francisco Chronicle)

    A solution to Darwin's 'mystery of the mysteries' emerges from the dark matter of the genome  Oct 27, 2009
    Bayes is now an HHMI postdoctoral research associate in the Department of Molecular and Cell Biology at the University of California, Berkeley. Grants from the National Institutes of Health, the Mathers Foundation and the Howard Hughes Medical Institute funded this research. (EurekAlert!)

    Common weed could provide clues on aging and cancer  Oct 27, 2009
    Dorothy Shippen, professor of biophysics and biochemistry at Texas A Carolyn Price, professor of cancer and cell biology at the UC College of Medicine, served as co-corresponding authors of the study. Telomeres are located at each end of a chromosome and are composed of DNA and protein. (EurekAlert!)

    USC Gets Millions in Stem Cell Funding  Oct 26, 2009
    The grants are intended to lead to advances in understanding the basic mechanisms underlying stem cell biology, cellular plasticity and cellular differentiation. Keck School of Medicine faculty members Martin Pera, PhD., director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, and Wange Lu, assistant professor of biochemistry ular biology, were among the 12 award recipients. (Los Angeles Downtown News, CA)

    1 shot of gene therapy and children with congenital blindness can now see  Oct 25, 2009
    The University of Pennsylvania Health System (UPHS) includes its flagship hospital, the Hospital of the University of Pennsylvania, rated one of the nation's top ten "Honor Roll hospitals by U.S.News Report; Pennsylvania Hospital, the nation's first hospital; and Penn Presbyterian Medical Center, named one of the nation's "100 Top Hospitals" for cardiovascular care by Thomson Reuters. In addition UPHS includes a primary-care provider network; a faculty practice plan; home care, hospice, and... (EurekAlert!)

    Mechanism For Neuron Self-preservation Discovered  Oct 25, 2009
    The study appears in the October 19, 2009 issue of the Journal of Cell Biology ... The Journal of Cell Biology, 2009; 187 (2): 279 DOI. (Science Daily)

    Reprogramming Patient's Eye Cells May Herald New Treatments Against Degenerative Disease  Oct 24, 2009
    (June 7, 2007) Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells. (Aug. (Science Daily)

    Making a cellular menagerie  Oct 24, 2009
    5-million stimulus grant has been awarded to the American Society for Cell Biology in Bethesda, Maryland, to establish an online open-access database called The Cell: An Image Library. The society is using the money to hire eight part-time annotators, who will help to compile images and videos for the site. (Scientific American)

    Trembling hands and molecular handshakes  Oct 24, 2009
    The basic approach focuses on gene regulation, but methods from structural biology, molecular cell biology, genetics, developmental biology and virology are all exploited in order to decipher the molecular mechanisms that underpin basic biological processes. Publication: "X-ray structure of Pur-alpha reveals a Whirly-like fold and an unusual nucleic-acid binding surface" Almut Graebsch, Stephane Roche, and Dierk Niessing. (EurekAlert!)

    Brigham and Women’s Hospital selects next president  Oct 23, 2009
    At the National Heart, Lung, and Blood Institute, one of 27 institutes making up the National Institutes of Health, Nabel focused on programs in stem cell biology, global health and chronic diseases in developing countries, health and prevention education, research by young scientists, and the genetics and genomics of heart, lung, and blood disease. For most of her tenure as director, the National Institutes of Health budget was flat, said Victor J. Dzau, chancellor for health affairs and chief... (Boston Globe)

    SIU faculty gets $2.6M in stimulus grants  Oct 22, 2009
    Edward Gershburg, assistant professor of medical microbiology, immunology and cell biology, Definition of Structural Organization and Enzymology of the EBV Protein Kinase, $63,682 ... William Halford, associate professor of medical microbiology, immunology and cell biology, Development of an Effective Genital Herpes Vaccine, $400,125. (St. Louis Business Journal, MO)

    Creation of new orthopedic research alliance announced  Oct 22, 2009
    VARI and TGen will head up most aspects of basic and applied research including the development and implementation of biomarkers, disease models, cell biology, genetics, imaging, and biomedical engineering. MSU, OAM and Spectrum will lead aspects of clinical research including clinical trials, treatments, education and prevention, and the collection and banking of biosamples and records. (EurekAlert! -- Business News)

    Henk Stunnenberg's lab applies Genomatix NextGen sequencing data analysis  Oct 21, 2009
    The Nijmegen Centre for Molecular Life Sciences (NCMLS) is a leading multidisciplinary research school within the domain of molecular mechanisms of disease and particularly in the fields of molecular medicine, cell biology and translational research. The research is focused in keeping with the mission towards understanding the cellular basis of disease. (EurekAlert! -- Business News)

    Clue hints at how breast cancer spreads  Oct 20, 2009
    And in singly moving cells, the signal is on when they move and off when they stop in a new place to grow, they reported in the journal Nature Cell Biology ... "The results helped us to find the set of genes that are behind the spread of breast cancer -- and that the genes need to be first turned on and then off in order for single cancer cells to be able to relocate," said Erik Sahai, head of the tumor cell biology lab at Cancer Research UK's London institute. (MSNBC -- Health)

    Barbara Ehrenreich questions positive thinking  Oct 20, 2009
    But Ehrenreich describes herself as a realist, an outlook that comes partly from her scientific training - she has a doctorate in cell biology. So how did we become so relentlessly positive. (San Francisco Chronicle)

    Fate Therapeutics announces creation of small molecule platform for commercial-scale reprogramming  Oct 19, 2009
    Fate Therapeutics is interrogating adult stem cell biology and applying induced pluripotent stem cell (iPSC) technology to develop Stem Cell Modulators (SCMs), small molecule or biologic compounds that guide cell fate for therapeutic purposes. Fate's SCM approach has broad therapeutic potential in areas such as regenerative medicine, hematological diseases, metastatic cancer, traumatic injury and degenerative diseases. (EurekAlert!)

    Skin Cells May Provide Early Warning For Cancer Risk Elsewhere In Body  Oct 17, 2009
    Harry Rubin, professor emeritus of molecular and cell biology at UC Berkeley, acknowledges that cancer cells have mutations in hundreds of genes, making it hard to determine which are the key triggers and making prognosis and treatment equally difficult. Even normal tissue differs from person to person because of a myriad of less disruptive mutations and because of different environmental exposures, both of which affect future cancer risk. (Science Daily)

    Promising Therapeutic Target For Central Nervous System Injuries Identified  Oct 17, 2009
    Flanagan's cell biology lab, however, recently discovered an anomaly a family of receptors on cells that tolerate and bind to the hard sugar coating itself. Flanagan wondered if one of these receptors might recognize CSPGs. (Science Daily)

    The food-energy cellular connection revealed  Oct 16, 2009
    Researchers who also contributed to the study include Uma M. Sachdeva and Craig B. Thompson at the Abramson Family Cancer Research Institute at the University of Pennsylvania School of Medicine in Philadelphia, Daniel F. Egan, Debbie S. Vasquez and Reuben Shaw in the Molecular and Cell Biology Laboratory, Elliot C. Williams and Henry Juguilon in the Gene Expression Laboratory as well as Luciano DiTacchio and Satchidananda Panda in the Regulatory Biology Laboratory, all at the Salk Institute for... (EurekAlert!)

    Exhibit intrigues young researchers  Oct 16, 2009
    The exhibit leads visitors of all ages through basic cell biology to promote understanding of tissue engineering and regenerative medicine, while also explaining current applications of the science and what the future holds. The exhibit also addresses ethical issues involved in the science. (Pittsburgh Post-Gazette, PA)

    Harvard team grows heart muscle from mouse stem cells  Oct 16, 2009
    The new work, to be published in the journal Science today, begins to confront what will be a major frontier for stem cell biology: translating recent basic science advances to meet the promise of regenerative medicine by finding ways to make such cells functional and potentially useful for therapies ... This represents, we think, an important step moving from stem cell biology in the heart to regenerative cardiovascular medicine, said Chien, who anticipates early stage clinical trials of cell... (Boston Globe)

    Gene Mutation May Reveal Clues For Treating Lung Diseases  Oct 16, 2009
    D., senior author and associate professor of anatomy and cell biology at McGill University in Montreal, Canada, compared various tissues from a mouse genetically engineered to be missing a form of the LTBP4 gene with skin tissue samples from one of the children ... The mouse, provided by Daniel Rifkin, M.D., the Charles Aden Poindexter Professor of Medicine and professor of cell biology at NYU Langone Medical Center, showed similar connective tissue alterations by electron microscopy as the... (Science Daily)

    Tragic Rarity: Baby Gets Mom's Cancer  Oct 15, 2009
    "We are pleased to have resolved this longstanding puzzle," said Mel Greaves, a professor of cell biology at the Institute of Cancer Research in the United Kingdom and the study's lead author in a release. "But we stress that such mother to offspring transfer of cancer is exceedingly rare and the chances of any pregnant woman with cancer passing it on to her child are remote.". (ABC News)

    Triggers Found In Cells' Transition From Colitis To Cancer  Oct 15, 2009
    "Ultimately it would be great if we could prevent colitis or treat colitis so it never gets to the cancerous stage," said UF colorectal surgeon Emina Huang, M.D., who is a member of the Program in Stem Cell Biology and Regenerative Medicine at UF's McKnight Brain Institute and the UF College of Medicine. Although colonoscopy is very effective in screening and preventing colon cancer for most people, for patients with colitis no diagnostic tests work well because the inflamed tissue makes... (Science Daily)

    Researchers Pave The Way For Effective Liver Treatments  Oct 14, 2009
    Brafman et al. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integrative Biology, 2009; 1 (8-9): 513 DOI. (Science Daily)

    Peptides in Anti-Aging Skin Care  Oct 12, 2009
    Peptides and Skin Cell Biology. Peptides are made of amino acids, the building blocks of proteins, an important component of all cells. (Suite101.com)

    UCSD researchers pave the way for effective liver treatments  Oct 10, 2009
    The findings were published in a paper entitled "Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with array combinatorial microenvironments" in the September 2009 issue of Integrative Biology ... "Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with array combinatorial microenvironments," Integrative Biology, September 2009. (EurekAlert!)

    Ribosomal Law and Order for Protein...  Oct 10, 2009
    Molecular Cell Biology. Fourth Ed., W. H. Freeman and Co., New York, N.Y.. (Suite101.com)

    Jefferson Medical College adds stem cell department  Oct 10, 2009
    Dr. Michael Lisanti will serve as chairman of the department of stem cell biology and regenerative medicine ... Lisanti will continue to serve as director of the Jefferson Stem Cell Biology and Regenerative Medicine Center at the Kimmel Cancer Center in Center City Philadelphia. (Philadelphia Business Journal, PA)

    Researchers identify mechanism that helps bacteria avoid destruction in cells  Oct 10, 2009
    Advances in cell biology and microbial genetics have greatly enhanced understanding of the cause and mechanisms of infectious diseases. Researchers from Thomas Jefferson University, the Pasteur Institute in Paris, and Yale University reported in PLoS ONE, a way in which intracellular pathogens exploit the biological attributes of their hosts in order to escape destruction. (EurekAlert!)

    Governor recognizes stem cell research at Einstein  Oct 9, 2009
    5 million in State funding for research to understand stem cell biology better and for improved efficiency in using existing stem cell lines ... D., Professor of Cell Biology (Basic Stem Cell Biology) ... D., Ingeborg and Ira Leon Rennert Professor of Stem Cell Biology and Regenerative Medicine (Blood Stem Cells). (EurekAlert!)

    High-sensitivity Bone Marrow Aspiration Technology Enhances Leukemia Cell Detection  Oct 8, 2009
    D., professor of medicine, cell biology, oncology and pathology, and vice dean for research at the Johns Hopkins University School of Medicine, believes this approach is quite different from the current standard. He suggested that the sensitivity compared to polymerase chain reaction still needs to be determined. (Science Daily)

    Gene That Regulates Breast Cancer Metastasis Identified  Oct 8, 2009
    In this study, which appears in the October on-line issue of Nature Cell Biology, Huang and colleagues introduced a genetic screen targeting 40,000 mouse genes into mammary tumor cells that do not usually spread, and then transplanted those cells to the mammary fat pads in mice where they would be expected to remain. Through RNA interference (RNAi) technology, they then reduced the expression of a metastasis-suppressor gene in five mice, one of which developed lung metastases in seven weeks. (Science Daily)

    Stanford scientists get stem-cell grant worth up to $40M  Oct 8, 2009
    The researchers will join the Progenitor Cell Biology Consortium, a collection of 17 teams of stem-cell researchers in the United States who are sharing $170 million in grants. In the first year, each of Stanford s four principal researchers will get between $1 million and $1. (East Bay Business Times, CA)

    TGen and Scottsdale Healthcare discover new 'pathways'  Oct 7, 2009
    "There are pathways that you can identify just from an in silico analysis. And we can use these types of tools to explore treatments for patients, down the road,'' said Dr. Weiss, an Associate Investigator in TGen's Cancer and Cell Biology Division and the senior author of the paper, which will appear in print in JTO's November edition. The study sought to identify metabolic pathways a series of chemical reactions occurring within a cell that could be targeted by drugs in patients with both... (EurekAlert!)

    New Technique Allows Scientists To Penetrate Yeast Cells' Hard Exterior  Oct 6, 2009
    Rockefeller University s Paul Nurse, president and head of the Laboratory of Yeast Genetics and Cell Biology, and Daniel Riveline, a visiting professor from the French National Center for Scientific Research (CNRS), have developed a technique that solves this problem. They used a tiny electric motor in conjunction with a pipette to saw an opening in the cell s tough outer coating. (Science Daily)

    All Tied Up: Tethered Protein Provides Long-sought Answer  Oct 6, 2009
    "It's become increasingly clear that many proteins are highly flexible and able to form different types of structures when they interact with something else, often another protein or DNA," said study co-author Kathleen Matthews, Rice's Stewart Memorial Professor of Biochemistry and Cell Biology, who began studying lactose repressor protein in 1970. "That's true for lactose repressor in binding to DNA, making it a good candidate to learn more about the process of DNA looping because it's a... (Science Daily)

    Nature Reviews journals  Oct 5, 2009
    Nature Reviews Molecular Cell Biology. Featured article. (Nature News Service)

    Need a New Heart? Grow Your Own.  Oct 4, 2009
    These are exciting times in stem cell biology, and there have been exponential advances, notes Chien, the MGH researcher. And at the same time, the gap between stem cell biology and true regenerative medicine has never been wider. (Boston Globe)

    'Natural Killer' Cells Keep Immune System In Balance  Oct 3, 2009
    The work reveals two important aspects of NK cell biology, the first piece being understanding how to keep NK cells instead of losing them, said Biron, the Esther Elizabeth Brintzenhoff Professor in the Department of Molecular Biology, Cell Biology and Biochemistry. The second is that if you can keep them around, they have an important regulatory function to limit adaptive immune response. (Science Daily)

    Southern Africa: Cassava Virus Dealt a Blow in Region  Oct 3, 2009
    Sarah Taylor, a researcher in the cassava biotechnology programme at the University of the Witwatersrand's School of Molecular and Cell Biology in Johannesburg, presented her research at the Bio2Biz conference in Durban last week (21-23 September). She says the new technology could be applied across the southern African region, as the same virus infects crops in Madagascar, Mozambique, the north eastern provinces of South Africa, Swaziland and Zimbabwe. (allAfrica.com)

    Skull Piece Thought to Be Hitler's Is from Woman  Sep 30, 2009
    Linda Strausbaugh, a professor of molecular and cell biology, got help from two former students who work in the New York City medical examiner's office. The former students, Craig O'Connor and Heather Nelson, are experts in working with challenging DNA samples and were able to extract enough DNA from the bone pieces to do a forensic study, Strausbaugh said. (Time.com)

    beware of falling coconuts  Sep 26, 2009
    NCBI ROFL is the brainchild of two Molecular and Cell Biology graduate students at UC Berkeley. Like most grad students, we procrastinate a lot. (Harper's Magazine)

    Mahlon Hoagland; biologist codiscovered transfer RNA  Sep 25, 2009
    In his later years, he wrote two popular books: The Way Life Works, an introduction to cell biology, and Exploring the Way Life Works, a biology textbook. He also used the other side of his brain, writing poetry and creating more than 40 wood sculptures. (Boston Globe)

    New Way Deadly Food-borne Bacteria Is Spread  Sep 25, 2009
    The process, which gradually overwhelms the second cell's ability to defend itself from infection, is featured in this week's edition of the science journal Nature Cell Biology. The plasma membrane, or outer layer, of healthy human cells normally exhibits tension. (Science Daily)

    Thomson Reuters Predicts Nobel Laureates  Sep 24, 2009
    -------------------------------------------------------------------------- James E. Rothman Wallace Professor of Biomedical Sciences, Professor and Chairman of Cell Biology, Professor of Chemistry, Yale University New Haven, Conn. USA -and- Randy Schekman Professor of Cell and Developmental Biology, University of California Berkeley; also, Howard Hughes Medical Institute Investigator Berkeley, Ca., USA -- For their research on cellular membrane trafficking. (PR Newswire)

    Photoswitches Shed Light On Spontaneous Free Swimming In Zebrafish  Sep 23, 2009
    Claire Wyart, post-doctoral fellow at UC Berkeley's Department of Molecular and Cell Biology, and UCSF post-doctoral fellow Filippo Del Bene are the joint first authors of a paper describing these results that appears in the Sept. 17 issue of the journal Nature ... "With these optically sensitive channels, it becomes possible to play back to the nervous system its normal innate activity and see what behavior results," added co-author Ehud Isacoff, UC Berkeley professor of molecular and cell... (Science Daily)

    How To Improve Vaccines To Trigger T Cell As Well As Antibody Response  Sep 19, 2009
    "It's not only that these killed or attenuated vaccines can't immunize, it's that they also suppress immunity," said co-author Daniel Portnoy, UC Berkeley professor of molecular and cell biology and of public health ... The findings support a new hypothesis about how the innate immune system distinguishes pathogenic from non-pathogenic microbes, proposed by Portnoy, UC Berkeley colleague Russell Vance, assistant professor of molecular and cell biology, and Ralph Isberg of Tufts University in the... (Science Daily)

    Light Controls Genetically Encoded Mouse Cells  Sep 19, 2009
    "This is a powerful tool for cell biology and cancer research," said Lim, who is a professor in the UCSF Department of Cellular and Molecular Pharmacology. "If you have a controllable 'light switch' that is generic enough to use in multiple cell functions, it gives you the ability to control where and when a cell moves, using a simple beam of light, and control what it does when it gets there.". (Science Daily)

    Police say no arrests imminent in Yale killing  Sep 18, 2009
    She was particularly interested in cell structure and cell biology, he said. Le was part of a research team headed by her faculty adviser, Anton Bennett. (ABC 7 News, DC)

    Drug discovery process more accurate, less expensive using novel mass spectrometry application  Sep 18, 2009
    CINCINNATICancer and cell biology experts at the University of Cincinnati (UC) have developed a new mass spectrometry-based tool they say provides more precise, cost-effective data collection for drug discovery efforts ... "If introduced broadly, the new generation mass spectrometry-based method we are proposing could significantly reduce the cost of running drug compound screening assays while also saving drug development teams substantial time by improving the accuracy of data collected,"... (EurekAlert!)

    With A Flash Of Light, A Neuron's Function Is Revealed  Sep 17, 2009
    This is a very unique way of arriving at an individual cell: by starting with the behavior it controls, says Ehud Isacoff, a biophysicist who holds joint appointments with Berkeley Lab s Physical Biosciences and Materials Sciences Divisions and UC Berkeley s Department of Molecular and Cell Biology. The research is an ongoing collaboration between Claire Wyart, a scientist in Isacoff s UC Berkeley lab, Filippo Del Bene of Herwig Baier s UC San Francisco lab, and Dirk Trauner of the University of... (Science Daily)

    Click to read:Yale Student's Slaying an Inside Job?  Sep 15, 2009
    Martin said Le was particularly interested in cell structure and cell biology, and he was pleased that she went on to pursue the field. He said the two exchanged a handful of e-mails over the years. (CBS News)

    Second-hand smoking results in liver disease, study finds  Sep 11, 2009
    "Our study provides compelling experimental evidence in support of tobacco smoke exposure playing a major role in NAFLD development," said , a professor of cell biology, who led the study. "Our work points to SREBP and AMPK as new molecular targets for drug therapy that can reverse NAFLD development resulting from second-hand smoke. Drugs could now be developed that stimulate AMPK activity, and thereby inhibit SREBP, leading to reduced fatty acid production in the liver.". (EurekAlert!)

    Individual Cells Isolated From Biological Clock Can Keep Daily Time, But Are Unreliable  Sep 11, 2009
    D., associate professor of cell biology and physiology in the School of Medicine, has demonstrated that individual cells isolated from the biological clock can keep daily time all by themselves. However, by themselves, they are unreliable. (Science Daily)

    Melanosome Dynamics And Sensitivity Of Melanoma Cells To Chemotherapy  Sep 11, 2009
    D., Michael M. Gottesman, M.D., of the Laboratory of Cell Biology at the National Cancer Institute in Bethesda, Md. and colleagues compared pigmentation and melanosome developmental stage, number, and cellular structures in melanoma cell lines in response to treatment with chemotherapeutic agents. (Science Daily)

    Fat-cell farms in the future for stem-cells?  Sep 10, 2009
    The findings were published by a team of researchers including Wu, an assistant professor of cardiology and radiology at Stanford University School of Medicine, and Dr. Michael Longaker, deputy director of Stanford's Stem Cell Biology and Regenerative Medicine Institute. The typical liposuction procedure removes one to two liters of fat from a patient, but cells can be grown from just 300 cubic centimeters, Wu said. (Palo Alto Online, CA)

    New Research Strategy For Understanding Drug Resistance In Leukemia  Sep 9, 2009
    Additional co-authors from UCSF include Doris Kim, Doan Le, MD, Michael Crone, Kimberly Krisman, Kegan Warner, Jeannette Bonifas, Qing Li, MD, Kristen Coakley, Ernesto Diaz-Flores, PhD, Matthew Gorman, MD, Mary Tran, Scott Kogan, MD, and Jeroen Roose, PhD. Co-authors from other institutions are Keiko Akagi, PhD, and Linda Wolff, PhD, of the National Cancer Institute; Sally Przybranowski, MS, and Judith Sebolt-Leopold, PhD, of Pfizer Global Research and Development; Neal Copeland, PhD, and Nancy... (Science Daily)

    Cancer drug may improve memory in Alzheimer's patients  Sep 7, 2009
    D., associate professor of pathology and cell biology in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain at Columbia University Medical Center. Dr. Arancio says that the cancer drug targets a previously unknown defect in the brains of mice with Alzheimer's. (EurekAlert!)

    Rogue protein 'spreads in brain'  Sep 7, 2009
    However, experts stressed the Nature Cell Biology study did not mean tau could be passed from person to person. This does not mean that these diseases are infectious in the same way as mad cow disease and human CJD. (BBC News -- Health)

    Lipid Involved With Gene Regulation Uncovered; Findings May Lead To Development Of Drugs To Fight Cancer  Sep 7, 2009
    D., professor and chair in the VCU Department of Biochemistry and Molecular Biology and co-leader of the VCU Massey Cancer Center's cancer cell biology program, reported that the cell nucleus, which contains the DNA that codes for all of our genes, also contains and produces S1P that is important for the regulation of certain genes. Researchers have known that the nucleus contains several kinds of lipids, but their functions have remained unknown until now. (Science Daily)

    Mitotic Release Of Chromatin-binding RNA Gives Insight Into X Chromosome Silencing  Sep 7, 2009
    In the August 24, 2009 issue of the Journal of Cell Biology, Hall et al. exploit the fact that XIST temporarily dissociates from the X chromosome during mitosis and find that Aurora B kinase helps regulate the RNA's chromatin binding ... Journal of Cell Biology, 2009; DOI. (Science Daily)

    Downregulation of protease activated receptor expression and cytokine production in P815 cells by RNA interference  Sep 7, 2009
    BMC Cell Biology 2009, 10:62doi:10. 1186/1471-2121-10-62. (BioMed Central)

    Researchers restore missing protein in rare genetic brain disorder  Sep 7, 2009
    Makoto Sato, in the University of Fukui Division of Cell Biology and Neuroscience, are also co-authors on the paper. The study was funded by Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture of Japan. (EurekAlert!)

    No comments posted.  Sep 6, 2009
    The grants are intended to lead to advances in understanding the basic mechanisms underlying stem cell biology, cellular plasticity and cellular differentiation. Keck School of Medicine faculty members Martin Pera, PhD., director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, and Wange Lu, assistant professor of biochemistry ular biology, were among the 12 award recipients. (Los Angeles Downtown News, CA)

    Reaching out to a new generation  Sep 6, 2009
    The faith of my parents had a great influence on all of us, said his sister, seven years younger than Sam and now in the final year of a Yale program to receive both a medical degree and a doctorate in cell biology. As an adult, Sam became a founder and elder of Bethany Presbyterian Church in Brookline. (Boston Globe)

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