Biologists Determine microRNA Activity Is Suppressed in Mouse Ovum Feb 7, 2010
The study, appearing in the journal Current Biology, was conducted by Schultz, Jun Ma and Paula Stein at Penn; Matyas Flemr, Radek Malik and Petr Svoboda of the Institute of Molecular Genetics, Academy of Sciences of the Czech Republic; and Philipp Berninger and Mihaela Zavolan of the University of Basel and Swiss Institute of Bioinformatics. The study was funded by the National Institutes of Health, a European Molecular Biology Organization's Strategic Development and Integration Grant and the... (Science Daily)
Finland invests 1.85 million in pan-European infrastructure for biomedical research Feb 4, 2010
Finland has made its first specific commitment to the development of European biomedical research infrastructures (BMS ESFRIs) by supporting a joint pilot infrastructure project in bioinformatics (ELIXIR), biobanking (BBMRI) and translational research (EATRIS) ... The approach that Finland has selected is based on the realization that significant potential synergies may arise from infrastructures developed for biobanking, bioinformatics and translational medical research. (EurekAlert! -- Business News)
Spherical Cows Help to Dump Metabolism Law Feb 4, 2010
The research, published in the journal Bioinformatics, could have significant implications for the environment and the way we. (Jan. (Science Daily)
UC Riverside's new state-of-the-art technology to accelerate stem cell research Feb 3, 2010
Talbot expects the SCCF to produce breakthroughs in stem cell research at a much faster pace than before, assisted by its Nikon BioStation CT incubator with a powerful microscope that already has generated useful data in conjunction with video bioinformatics ... "The BioStation technology coupled with UCR's expertise in video bioinformatics will greatly facilitate our ability to understand dynamic cell processes and will provide data essential for attacking degenerative disease," Talbot said. (EurekAlert! -- Business News)
High-throughput analysis of gene regulation, DNA synthesis in Cold Spring Harbor Protocols Feb 2, 2010
Since 1933, it has furthered the advance and spread of scientific knowledge in all areas of genetics and molecular biology, including cancer biology, plant science, bioinformatics, and neurobiology. It is a division of Cold Spring Harbor Laboratory, an innovator in life science research and the education of scientists, students, and the public. (EurekAlert!)
Promising new neuroimaging techniques for early detection of Alzheimer's disease Jan 31, 2010
Amsterdam, January 29, 2010 Investigators from the International Center for Biomedicine and the University of Chile, in collaboration with the Center for Bioinformatics of the Universidad de Talca, have discovered that two drugs, the benzimidazole derivatives lanzoprazole and astemizole, may be suitable for use as PET (positron emission tomography) radiotracers and enable imaging for the early detection of Alzheimer's Disease. The study is published in the current issue of the Journal of... (EurekAlert!)
New computational tool for cancer treatment Jan 30, 2010
Researchers in the Molecular Modeling group at the SIB Swiss Institute of Bioinformatics and Dr. Benot J. Van den Eynde's group at the Ludwig Institute for Cancer Research Ltd (LICR) Brussels Branch developed an approach for creating new IDO inhibitors by computer-assisted structure-based drug design ... According to Olivier Michielin, Assistant Member at the Lausanne Branch of LICR and leader of the SIB Swiss Institute of Bioinformatics Molecular Modeling group, "This is a satisfactory proof... (EurekAlert!)
Towards the integration of mouse databases - definition and implementation of solutions to two use-cases in mouse functional genomics Jan 22, 2010
The use-cases created, and their prototype software implementations should help to better define biologists' needs for database integration and may serve as a starting point for future bioinformatics solutions aimed at end-user biologists. The complete article is available as a. (BioMed Central)
National Cancer Institute seeks tools for electronic data management Jan 21, 2010
In November, the institute to harmonize the data elements on the bioinformatics grid for the purpose of improved information sharing. About the Author. (FCW.com)
Open Access Drug Discovery Database Launches With Half a Million Compounds Jan 20, 2010
The database is hosted by the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI). It was transferred from biotech firm Galapagos NV in July 2008 through a 4. (Science Daily)
Membrane-coat proteins: Bacteria have them too Jan 20, 2010
Using a combination of bioinformatics, molecular biology and electron microscopy, the EMBL scientists found that proteins with the characteristic membrane-coat architecture also exist in members of the PVC group, but not in any other bacteria, in association with the membranes of subcellular compartments. "Our findings provide unexpected clues as to how the endomembrane system of eukaryotes evolved," says Damien Devos, who led the study, "and since they are relatively simple cells, these... (EurekAlert!)
GU Given Research Funding Jan 17, 2010
Other grants have been awarded to Richard Weiss, a professor in the chemistry department, and Hongfang Liu, an assistant professor in the department of biostatistics, bioinformatics and biomathematics, among others. According to a university statement, over 200 Georgetown grant proposals remain pending. (The Hoya, Washington DC)
Parasitic wasps' newly sequenced genomes reveal new avenues for pest control Jan 16, 2010
Researchers from the University of Geneva and the SIB Swiss Institute of Bioinformatics led an analysis of the sequenced genomes of parasitic wasps ... Professor Evgeny Zdobnov from the University of Geneva Medical School and the SIB Swiss Institute of Bioinformatics directed the comparative evolutionary genomics studies as part of this international project, which revealed many features that could be useful to pest control and medicine, and to enhance our understanding of genetics and evolution... (EurekAlert!)
Sunflower Genome Holds the Promise of Sustainable Agriculture Jan 15, 2010
Dr. Nolan Kane (University of British Columbia) is one of the co-investigators on the project and together with colleagues at INRA in France, is doing much of the bioinformatics for the genome project. "The sunflower genome is 3.5 billion letters long -- slightly larger than the human genome. The sunflower family is the largest plant family on earth -- encompassing several important crops and weeds. Mapping its genome will create a very useful reference template for the entire plant family,... (Science Daily)
Genome sequencing shows past genetic events made soybeans rich in versatile gene families Jan 14, 2010
What makes soybean somewhat unique as a polyploid, according to Jessica Schlueter, a faculty member in Bioinformatics at the University of North Carolina at Charlotte and the paper's third author, is the fact that most of the plant's copied genes diverged to become new genes rather than disappearing, which is the more common evolutionary result of gene duplication. "One of the characteristics that we've known from studies in soybeans is that there is an over-abundance of multi-gene families,"... (EurekAlert!)
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach Jan 14, 2010
BMC Bioinformatics 2010, 11:27doi:10. 1186/1471-2105-11-27. (BioMed Central)
Key ingredient missing from e-health records, advisers say Jan 14, 2010
HHS lack of a provision ensuring capture of the physician narrative within certified digital health record systems could be one of the missed opportunities in the regulation, according to testimony presented by Paul Tang, co-chairman of the panels workgroup on meaningful use and chief medical information officer of the Palo Alto Medical Foundation, and George Hripcsak, workgroup co-chairman and bioinformatics professor at Columbia University. HHS also apparently missed a chance to... (FCW.com)
Researchers Study Microbes in Cattle to Unlock Metabolic Disease Mysteries Jan 11, 2010
The team's current work has focused on bacterial populations in the rumen using sequencing methods and bioinformatics to classify which bacterial genera are present under different dietary conditions. The bloat team recently completed the first genomics-based characterization of bacterial populations from steers associated with changing from a warm-season grass hay diet to a cool-season grazed forage diet. (Science Daily)
Virginia Tech licenses GenoCAD source code to ISCB Jan 10, 2010
"Our initial vision for GenoCAD was to develop a web site allowing users to design synthetic genetic systems for biological research or product development programs," said Jean Peccoud, associate professor at the Virginia Bioinformatics Institute at Virginia Tech ... Scott Markel, ISCB Vice President and Chair of the Publications Committee, remarked: "We are extremely pleased to enter into what we see as a first-of-kind relationship between our organization and academic institutions looking to... (EurekAlert! -- Business News)
Short school closures won't stop flu Jan 10, 2010
"Since children are more susceptible to most influenza strains than adults, closing schools seems an obvious strategy to slow the spread of flu," Philip C. Cooley, assistant director of bioinformatics at RTI and a co-author of the study, said in a news release from RTI, a research institute. "However, computer simulations indicate that such closures are ineffective unless they are sustained for at least eight weeks after implementation.". (Atlanta Journal-Constitution -- Health)
