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D., vice president of therapeutic development for Targeted Genetics, presented the data in an oral presentation at the 11th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle. To clarify, the data demonstrated that a 30 percent decrease in the global visual analog scale (VAS) was experienced by 21/50 (42 percent) of subjects and 3/16 (19 percent) placebo subjects 12 weeks after the first injection. (PR Newswire)
AMT Announces Positive Interim Clinical Data on its Lead Product AMT-011 May 30, 2008
AMSTERDAM, May 30 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, today announced that positive interim data from its pivotal clinical trial with AMT's lead product Glybera(R) (AMT-011) were presented by the Principal Investigator, professor Daniel Gaudet, at the American Society of Gene Therapy Annual Meeting in Boston on May 29th ... Study data Glybera(R) is a gene therapy product that corrects the genetic defect in... (PR Newswire)
Oncolytics Biotech Inc. Collaborators to Present Reovirus Research at ASGT Meeting May 30, 2008
CALGARY, May 30 /CNW/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced today that two presentations covering preclinical work using the reovirus are scheduled to be delivered by Dr. Richard Vile of the Mayo College of Medicine, Rochester, Minnesota, at the American Society of Gene Therapy (ASGT) annual meeting in Boston, MA. The meeting runs from May 28 to June 1, 2008. A poster presentation entitled "Combination Immunotherapy and Oncolytic Virotherapy for the Treatment of Malignant... (Canada Newswire)
Gene Therapy Increases Survival For End-stage Head And Neck Cancer May 30, 2008
ScienceDaily (May 29, 2008) A gene therapy invented at The University of Texas M. D. Anderson Cancer Center is the first to succeed in a U.S. phase III clinical trial for cancer, as announced May 28 at the American Society of Gene Therapy annual meeting in Boston ... Roth's lab has been developing gene therapy for cancer since 1990 ... Roth found little interest in gene therapy from established pharmaceutical companies, so in 1994 he co-founded Introgen working through M. D. Anderson's Office of... (Science Daily)
Q&A: The Man Behind Embryonic Stem Cells May 29, 2008
People thought gene therapy would be here, and it hasn't happened. Nobody ever predicted the genome project would be done at this point. (Forbes -- Business)
New Cheaper Method For Mapping Disease Genes May 28, 2008
28, 2000) Gene therapy which aims to replace "bad" genes with useful ones has yet to live up to its promise largely because of problems delivering genes to the right place in the body. . (Science Daily)
AMT's Cooperative Research and Development Agreement With NIH to Boost Production Capacity May 26, 2008
AMSTERDAM, The Netherlands, May 26 /PRNewswire-FirstCall/ -- - Production Increase Brings Large Disease Areas within Reach Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, today announced that it obtained a Cooperative Research and Development Agreement from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH), Bethesda, Maryland, that promises to substantially enhance the power of AMT's gene therapy... (PR Newswire)
'Intrabody' can mop up mutant protein in Huntington's disease model May 26, 2008
Delivering the intrabody to brain tissues in people would be a formidable challenge, because it would require some form of gene therapy. However, it may be possible to use information about the intrabody's structure to find drugs that mimic its effects, Li says. (EurekAlert!)
Gene Therapy May 24, 2008
Search post-gazette NOW. Do You Even Watch the Game. (Pittsburgh Post-Gazette, PA)
Gene Therapy: Oral Gene Delivery System For Inflammatory Bowel Disease Works, Study Shows May 23, 2008
The article discusses the effectiveness of oral interleukin-10 or IL-10 (anti-inflammatory protein molecules) gene therapy for the treatment of IBD. The findings indicate that upon oral administration of NiMOS, transfection and local expression of IL-10 can not only suppress the levels of pro-inflammatory cytokines, but can also increase body weight, restore colon length and weight, and suppress inflammatory tissue response ... Over the course of eight days of oral gene therapy treatment, the... (Science Daily)
Neural Cell Transplants May Help Those With Parkinson's Disease May 23, 2008
"There are currently a number of clinical trials underway using direct gene therapy approaches to deliver potent trophic factors throughout the basal ganglia.". Emborg and colleagues report that hNPCs genetically modified to over-express GDNF were able to survive transplant and produced GDNF for three months, and that functional recovery in test animals increased while no obvious negative side effects from the transplant procedure were observed. (Science Daily)
AMT Accesses Technology for Treatment of Duchenne Muscular Dystrophy May 22, 2008
AMSTERDAM, The Netherlands, May 22 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, today announced that it obtained a license from La Sapienza University in Rome, Italy, to their advanced small nuclear RNA (snRNA)-based exon-skipping technology for the treatment of Duchenne muscular dystrophy (DMD). The combination with AMT's proprietary adeno-associated virus (AAV) gene therapy platform potentially makes up a long-term... (PR Newswire)
Improved Gene Therapy Agent Is 30 Times More Efficient Than Current One May 22, 2008
ScienceDaily (May 21, 2008) Replacing one amino acid on the surface of a virus that shepherds corrective genes into cells could be the breakthrough scientists have needed to make gene therapy a more viable option for treating genetic diseases such as hemophilia, University of Florida researchers say ... Reporting in the journal Proceedings of the National Academy of Sciences May 19, UF geneticists say they have developed a new version of the adeno-associated virus used in gene therapy that works... (Science Daily)
Blood-clotting Protein Modified For People With Hard-to-treat Hemophilia May 22, 2008
ScienceDaily (May 21, 2008) Pathologists at The University of Texas Health Science Center at Houston have developed a chemically modified protein that may help people with a hard-to-treat form of a genetic bleeding disorder known as Hemophilia A.. With a shortage of the blood-clotting protein Factor VIII (FVIII), people with Hemophilia A typically receive injections of FVIII derived from plasma or produced synthetically to control potentially life-threatening episodes of bleeding. (Science Daily)
Gene Therapy May Treat Erectile Dysfunction May 22, 2008
TUESDAY, May 20 (HealthDay News) -- Gene therapy may be a way to treat erectile dysfunction in men who do not respond to pills such as Viagra, researchers report. Maxi-K gene therapy is a gene transfer that improves erectile dysfunction. (MEDLINEplus)
Gene Therapy for Retinal Degeneration May 22, 2008
In this issue of the Journal, two groups of investigators Bainbridge et al.1 and Maguire et al.2 describe the first results of separate clinical trials investigating the short-term safety and preliminary efficacy of gene therapy for Leber's congenital amaurosis. Both groups present short-term data (12 months and 5 months, respectively) on three patients with Leber's congenital amaurosis in each study; the patients were enrolled in trials of recombinant adeno-associated viral delivery of the... (New England Journal of Medicine)
Effect of Gene Therapy on Visual Function in Leber’s Congenital Amaurosis May 22, 2008
NEJM -- Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis ... Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis. (New England Journal of Medicine)
Dr. Gupta: The Prognosis for Kennedy May 22, 2008
There is also a type of gene therapy that injects custom-made viruses into tumor cells, causing them to die or at least become more susceptible to radiation. These aren't great choices, which means the Senator may have to rely as much on his own strength and optimism as on modern medicine. (Time.com)
Frequently asked questions about MPS May 21, 2008
Researchers are hoping gene therapy will offer a cure for MPS someday. Comments. (San Francisco Chronicle)
Scientists 'paint' viruses to track their fate in the body May 21, 2008 Vaccine Triggers Immune Response, Prevents Alzheimer's In Mice May 20, 2008 UF researchers develop improved gene therapy agent May 20, 2008 Gene Drugs For Untreatable Diseases May 15, 2008 Gene Therapy Found to Slow Progression of Fatal Brain Condition May 15, 2008 Gene Therapy Clinical Trial Yields Promising Results For Batten Disease May 15, 2008 Gene Therapy Shows Promise in Rare Brain Disease May 15, 2008 ASK THE EXPERTSHow does gene therapy work? May 14, 2008 Subsc00001174ribe May 14, 2008 Arthritis Is A Potential Barrier To Physical Activity For Adults With Diabetes May 11, 2008 Suspected Cause Of Type 1 Diabetes Caught 'Red-handed' For The First Time May 11, 2008 Skin Flaps Deliver Cancer-fighting Therapy, Study Reveals May 10, 2008 Opinion: Freebie ban is insulting to docs May 8, 2008 Naturally-occuring Protein May Be Effective In Limiting Heart Attack Injury And Restoring Function May 8, 2008 Double Duty: Loss Of Protective Heart Failure Protein Causes High Blood Pressure May 8, 2008 Stem Cell Researchers Demonstrate Safety Of Gene Therapy Using Adult Stem Cells May 8, 2008 Gene therapy shines light on blindness May 3, 2008 Charlie Crist May 2, 2008 Revolutionary Eye Procedure Helps Improve Vision in Youth May 2, 2008 Engineers Harness Cell Phone Technology For Use In Medical Imaging May 2, 2008 Anti-Aging Breakthroughs May 2, 2008 Tiny Magnets Offer Breakthrough In Gene Therapy For Cancer Apr 22, 2008 Two blind men are given partial sight by implant Apr 22, 2008 Inflammation triggers cell fusions that could protect neurons, Stanford research shows Apr 21, 2008 Clearer Day For Gene Therapy: New Vector Carries Big Genes Linked To Inherited Blindness Apr 20, 2008 Gene Therapy For Addiction: Flooding Brain With 'Pleasure Chemical' Receptors Works On Cocaine, As On Alcohol Apr 19, 2008 In Blood Vessel Stents, Innovative Materials Allow Better Control, Delivery Of Gene Therapy Apr 19, 2008 Ovarian Cancer Stem Cells Identified, Characterized Apr 19, 2008 Gene Therapy in Rats Reduces Cocaine Use Apr 19, 2008 New drug Lapatinib shrinks breast cancer Apr 19, 2008 Tiny magnets used in anti-cancer test Apr 18, 2008 Oncolytics Biotech Inc. Announces Gene Therapy Publication on Reovirus Treatment for Melanoma Apr 16, 2008 Boosting awareness tenfold Apr 15, 2008 Synthetic Molecules May Be Less Expensive Alternative To Therapeutic Antibodies, Researchers Find Apr 9, 2008 JAMA article looks at data-sharing in clinical trials for heart disease Apr 9, 2008 Parkinson's brain cell transplants last years Apr 7, 2008 Bradmer announces new additions to management team Apr 2, 2008 Magnificent vacations on Mars Apr 2, 2008 Boy, 6, battlescancer, raises$900 for hospital Mar 30, 2008 Could Schizophrenia Be Entirely Genetic? Mar 30, 2008 CCA hosts scavanger hunt to benefit student Mar 30, 2008 Long-term Use Of Mechanical Ventilation Contributes To The Deterioration Of Human Diaphragm Muscle Mar 29, 2008 MRI Findings Help Forecast Prostate Cancer Prognosis Mar 28, 2008 Umbilical cord blood cell therapy in an animal model of Alzheimer's disease Mar 27, 2008 US seeks new focus for AIDS vaccine Mar 26, 2008 Gene Therapy Can Cause Leukemia In Large Animals Mar 24, 2008 Safer Gene Therapy May Be Possible Using Novel Approach Mar 22, 2008 How Stealthy HIV Protein Gets Into Cells Mar 21, 2008 Amsterdam Molecular Therapeutics to Appoint Alexander Ribbink to Supervisory Board Mar 20, 2008 Blood Vessel Protein Reverses Macular Degeneration, Diabetic Retinopathy In Mice Mar 19, 2008 Way to target genes devised for gene therapy Mar 19, 2008 Regaining Lost Luster Mar 18, 2008 New Drug Protects Nerve Cells From Damage In Mice Mar 18, 2008 Tobacco plants get gene therapy Mar 18, 2008 Work with power grids leads to cell biology discovery Mar 18, 2008 Scientists shine new light on inflammatory diseases Mar 17, 2008 Gene Therapy Could Save Kids From A Lifetime Of Eating Cornstarch Mar 15, 2008 New chemical can kill latent tuberculosis bacteria Mar 15, 2008 London shares outlook - lower, ahead of UK Budget Wednesday, US recession fears Mar 10, 2008 Biotech turns to hair-loss research Mar 8, 2008 Bone docs look to biology for future Mar 7, 2008 Cellular Construction Methods Emulated at Nano-scale Mar 6, 2008 Prima donna cricketers need to be weeded out of game Mar 1, 2008 Start On Way To Baldness Gene Therapy? Feb 27, 2008 Out-of-whack protein may boost Parkinson's Feb 27, 2008
This breakthrough should give a much-needed boost to the efficiency of some forms of gene therapy, help track and treat viral disease and evolution, improve the efficiency of vaccines, and ultimately allow health care professionals track the movement of viral infections within the body. Specifically, the new method should make it easier to track and treat infectious diseases such as HIV/AIDS, influenza, hepatitis C, and dengue fever. (EurekAlert!)
A WISH TO WALK: Part III: 'I can't believe that it couldn't happen' May 20, 2008
Gene therapy carries the potential to provide the injured spinal cord with the specific gene products, or proteins, that it needs to promote functional recovery. Gene therapy is not a current treatment for spinal cord injuries but is being studied with animal models of spinal cord injury. (Orangeburg Times and Democrat, SC)
The Rochester scientists reported the findings in an article in the May issue of Molecular Therapy, the journal of The American Society of Gene Therapy. "Our study demonstrates that we can create a potent but safe version of a vaccine that utilizes the strategy of immune response shaping to prevent Alzheimer's-related pathologies and memory deficits," said William Bowers, associate professor of neurology and of microbiology and immunology at the Medical Center and lead author of the article. (Science Daily)
Replacing one amino acid on the surface of a virus that shepherds corrective genes into cells could be the breakthrough scientists have needed to make gene therapy a more viable option for treating genetic diseases such as hemophilia, University of Florida researchers say. Reporting in the journal Proceedings of the National Academy of Sciences today (May 19), UF geneticists say they have developed a new version of the adeno-associated virus used in gene therapy that works about 30 times more... (EurekAlert!)
Previous attempts by other drug companies to harness gene therapy have, at times, had disastrous results. In one trial in 1999, an 18-year-old patient died; in a separate trial in France, a child developed leukemia. (Forbes -- Technology)
An experimental gene therapy had positive effects in slowing the progression of Batten disease, or Late Infantile Neuronal Ceroid Lipofuscinosis (LINCL), a team of New York-Presbyterian Hospital/Weill Cornell Medicine Center physician-scientists showed ... The genes are incorporated within the genetic material of the cells, which are then able to produce a protein that is deficient in Batten disease, Crystal reported in a paper entitled Treatment of Late Infantile Neuronal Ceroid... (eFluxMedia)
ScienceDaily (May 14, 2008) Promising results from a team of NewYork-Presbyterian Hospital/Weill Cornell Medical Center physician-scientists show that gene therapy is both safe and effective at slowing the progression of Batten disease, or Late Infantile Neuronal Ceroid Lipofuscinosis (LINCL), a rare, genetic, degenerative neurological disorder that usually becomes fatal in children by the age of 8 to 12 ... Dr. Crystal is a world leader and pioneer in the use of gene therapy to treat a number... (Science Daily)
WASHINGTON (Reuters) - An experimental gene therapy treatment appears to have helped eight children with a rare and incurable neurological disorder, although it may have been responsible for the death of one, researchers reported on Tuesday ... Like all forms of gene therapy, the hope is that the mutant cells will take up the new gene and start working normally ... "The disease is caused by mutations in the CLN2 (ceroid lipofuscinosis, neuronal 2) gene," Crystal and colleagues wrote in their... (MEDLINEplus)
How does gene therapy work ... How does gene therapy work ... and president of the American Society of Gene Therapy, responds. (Scientific American)
Subscription Step 1 - Product Selection. Select if you are buying online access for multiple users. (Nature News Service)
ScienceDaily (May 10, 2008) People with diagnosed diabetes are nearly twice as likely to have arthritis, and the inactivity caused by arthritis hinders the successful management of both diseases, according to a new Morbidity and Mortality Weekly Report (MMWR) study released May 8 by the Centers for Disease Control and Prevention (CDC). This is one of the first studies of its kind to look at the relationship between arthritis and diabetes and the outcomes associated with physical activity. (Science Daily)
2, 2006) Using state-of-the-art gene therapy techniques, University of Pittsburgh investigators have successfully prevented the onset of elevated blood sugar, or hyperglycemia, in diabetes-prone mice by. (May 7, 2008) Researchers in Maine report a new explanation for the mysterious link between consumption of cows' milk protein in infant formula early in life and an increased risk of later developing Type-1. (Science Daily)
ScienceDaily (May 9, 2008) Using gene therapy, plastic surgeons have delivered cancer fighting proteins through skin flaps placed on cancerous tumors on rats with a 79 percent reduction in tumor volume, according to a study in the May issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons ... "This new technique may allow us to reprogram skin flaps, using gene therapy, to provide a blueprint for anti-tumor agents like Interleukin-12... (Science Daily)
So students and residents enjoy your pizza sit down, learn about a new heart valve, a new antibiotic, a new advance in gene therapy and get on with your duties to your patients. Click for related content. (MSNBC -- Terrorism)
7, 2004) A novel gene therapy that responds specifically to oxygen-starved heart muscle may protect against further injury following a heart attack, a study by University of South Florida cardiovascular. (May 27, 2002) University of Melbourne researchers, along with doctors and scientists from eight Melbourne hospitals, have located three genes that make heart attack more likely. (Science Daily)
D, director of the Center for Translational Medicine, they have proven that loss of the protein causes diseased hearts to fail and that the protein is a potential target for gene therapy for heart failure ... (May 24, 2007) Heart researchers have used gene therapy to reverse heart failure in animals. (Science Daily)
ScienceDaily (May 7, 2008) A new study by UC Davis researchers provides evidence that methods using human bone marrow-derived stem cells to deliver gene therapy to cure diseases of the blood, bone marrow and certain types of cancer do not cause the development of tumors or leukemia ... None of the transplanted mice developed leukemia or solid tumors caused by the gene therapy treatment, during the evaluation period of up to 18 months ... Gene therapy trials using human bone marrow cells began in... (Science Daily)
Mr. Turner, 21, recently became the first Canadian, and one of a handful of patients in the world, to receive an experimental gene therapy for a rare hereditary eye disease called Leber congenital amaurosis (LCA) ... If further tests show the treatment works, experts say the gene therapy - which involves replacing faulty genes with normal ones - has the potential to reverse blindness from other kinds of inherited eye diseases ... "There are so many inherited eye diseases that it makes great... (Globe and Mail)
The Vaccine and Gene Therapy Institute was established in 2001 by Oregon Health & Science University, and has about 90 employees. Its research mission centers around viral infectious diseases and vaccine development. (Portland Business Journal, OR)
The new procedure involved gene therapy, which the doctors used to regenerate the dying cells in Howarths right eye ... Its been done here in the UK with the expertise of the NHS and the science and research of the Department of Health all coming together to offer such hope not only for gene therapy for the correction of sight - but also for gene therapy generally. (The Money Times)
The National Center for Research Resources at the U.S. National Institutes of Health (NIH) is supporting Rubinsky's research on the use of EIT to control gene therapy and cancer treatment in patients. The findings reported in the PLoS ONE paper demonstrate that these advanced medical technologies, which are dependent on EIT imaging, are not restricted to highly industrialized locations. (Science Daily)
These days the buzzwords are anti-oxidants, enzymes, gene therapy and nano molecules. If you have some fine lines, a few wrinkles but you're not yet ready for the "f" word (facelift), an anti-aging cream might be right for you. (ABC News)
Using human cells as delivery vehicles for anti-cancer gene therapy has long been an attractive approach for treating tumours, but these cells usually reach tumours in insufficient numbers to effectively attack them ... The technique involves inserting nanomagents into monocytes - a type of white blood cell used to carry gene therapy - and injecting the cells into the bloodstream ... The head of the laboratory in which the work was done, Professor Lewis, explains: "The use of nanoparticles to... (Science Daily)
David Head, of the British Retinitis Pigmentosa Society, said: "These are significant advances. Taken in conjunction with the advances being made in stem cell therapy and gene therapy, they make for really exciting times as we work to translate science into treatment.". But Professor John Marshall, chairman of the BRPS medical advisory board, warned that it was still "very early days". (Mirror.co.uk)
The surprise finding in mice suggests that the creation of the fused cells, called heterokaryons, may possibly play a role in protecting neurons against damage and may open new doors to cell-mediated gene therapy. "This finding was totally unprecedented and unexpected," said senior author Helen Blau, PhD, the Donald E. and Delia B. Baxter Professor and director of the Baxter Laboratory in Genetic Pharmacology. (EurekAlert!)
19, 2008) For some inherited diseases, one barrier to successful gene therapy is that a commonly used vector (package into which the curative gene is placed) cannot accommodate the large size of the curative gene ... Some clinicians and researchers hope that individuals with inherited diseases (such as cystic fibrosis and recessive Stargardt disease, which causes progressive loss of sight) might one day be cured by providing them with a corrected version of their disease-causing faulty gene,... (Science Daily)
14, 2001) Scientists at the U.S. Department of Energy's Brookhaven National Laboratory report in the current Journal of Neurochemistry (Volume 78, Number 5) that they used gene therapy techniques to. (Nov. (Science Daily)
18, 2008) Before gene therapy becomes practical for treating human diseases, researchers must master the details of safe and effective delivery. Cardiology researchers at The Children's Hospital of Philadelphia have advanced delivery techniques by creating a versatile synthetic material that can bind to a variety of gene therapy vectors and can be custom-designed for controlled local release of therapeutic genes at a disease site ... Adenovirus served as a gene therapy vector to carry genes for... (Science Daily)
16, 2007) Researchers recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use. . (Science Daily)
FRIDAY, April 18 (HealthDay News) -- Using gene therapy to increase the level of dopamine -- a pleasure-related chemical -- receptors in rats' brains reduced their desire for cocaine by 75 percent, U.S. researchers say. Previous research by the same team at the U.S. Department of Energy's Brookhaven National Laboratory, in Upton, N.Y., found that increasing the level of dopamine receptors reduced rats' desire for alcohol. (Health-Finder)
The technique, which combines nanotechnology and gene therapy, could help specially armed human immune cells to home in on cancer cells to destroy them ... Details are published in the journal Gene Therapy. (Times Online)
Gene therapy technique attacks tumors in lab tests ... LONDON - Tiny magnets have been used to deliver anti-cancer gene therapy in mice in a development that could make the treatment much more effective, scientists said on Thursday ... The idea behind gene therapy is to replace faulty genes. (MSNBC -- Health)
Alan Melcher and his research group at St. James's University Hospital in Leeds, U.K. published the results of their work in the April 10 online issue of Gene Therapy ... Forward-looking statements, including the implication of the materials published in "Gene Therapy" with respect to REOLYSIN(R), the Company's expectations related to the results of trials investigating delivery of REOLYSIN(R), and the Company's belief as to the potential of REOLYSIN(R) as a cancer therapeutic, involve known and... (Canada Newswire)
The fact that the Myositis Association provided funding for a study that sounds like a breakthrough in gene therapy is very exciting, but they re going to need more money to participate in the FDA trials. Riddle has also been in touch with the clothing company Life is Good, whose charitable works include a kids foundation to support children in need. (Bolton Common, MA)
In future, gene therapy should make it possible to introduce genes into. (Jan. (Science Daily)
Weill Cornell physician-scientists have been responsible for many medical advances -- from the development of the Pap test for cervical cancer to the synthesis of penicillin, the first successful embryo-biopsy pregnancy and birth in the U.S., the first clinical trial for gene therapy for Parkinson's disease, the first indication of bone marrow's critical role in tumor growth, and, most recently, the world's first successful use of deep brain stimulation to treat a minimally-conscious... (EurekAlert!)
"If you ask me whether this spells doom and gloom for cell replacement, the answer is absolutely not," said Kordower, who is pursuing another treatment for Parkinson's by using gene therapy to repair the damaged cells. Isacson found no such damage in the brains of five patients who died nine to 14 years after getting transplants. (MSNBC -- Health)
In 2005-2006 he served as Vice-President Manufacturing for Genetix Pharmaceuticals, where he successfully led the cGMP manufacturing of the first clinical recombinant Lentivirus biologic for hemophilia gene therapy. He was Project Manager in the Biodefense Medical Systems Department of the Battelle Memorial Institute for four years and from 1997-2000 he served as the Director of Biologics for Novopharm Biotech. (Canada Newswire)
It's gene therapy at its easiest, and most luxurious, at the Tessier-Ashpool Orbital Clinic. The T-A's doctors regularly work on famous celebs and CEOs, but don't ask for names. (MSNBC -- Travel)
Current research includes work on gene therapy, bone marrow transplant, chemotherapy, viruses and pediatric AIDS.. Almost 5,000 patients are treated at St. Jude annually, most on an outpatient basis. (Daytona Beach News Journal)
In regards to gene therapy, I am all for it albeit, the therapy is done ethically and is used to better people s lives. However, I wish I knew more about Oriental medicine. (MedHeadlines)
The trial, which uses gene therapy, could actually make it possible for Matthew to see fully again, said Nina Stairs, Matthew's mother. Proceeds from the scavenger hunt will go toward paying for Matthew to be part of the trial. (Casper Star-Tribune, WY)
8, 2004) University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm muscle of mice with inherited respiratory weaknesses, enabling them to breathe. (Jul. (Science Daily)
24, 2003) A novel approach that combines gene therapy and radiation therapy for treating prostate cancer has shown promising results for its safety and effectiveness, according to Henry Ford Hospital. (Apr. (Science Daily)
com) is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Cloning and Stem Cells, Human Gene Therapy, and Tissue Engineering. Its biotechnology trade magazine, Genetic Engineering chnology News (GEN), was the first in its field and is today the industrys most widely read publication worldwide. (EurekAlert!)
"It's a great model. I'm not sure we've used it to best advantage," said Louis Picker, associate director of the Vaccine and Gene Therapy Institute at Oregon Health and Sciences University. But other participants cautioned against moving too far from clinical research. (Boston Globe)
23, 2008) Individuals with a number of life-threatening genetic diseases of the immune system have been successfully treated by gene therapy -- that is, they were infused with early precursors of immune cells that had the correct form of the defective gene delivered into them by agents known as retroviral vectors ... This slowed progress in the field and has led to detailed studies seeking to determine the mechanisms underlying the cause of leukemia and whether other genes that are candidates... (Science Daily)
21, 2008) A novel strategy for circumventing safety problems that have plagued gene therapy has been offered by a complex multicenter group of researchers, including Professor Claudio Napoli, a Full Professor at the II University of Naples and Adjunct Professor at the Sbarro Research Institute for Cancer Research and Molecular Medicine and the Center of Biotechnology at the College of Science and Technology of Temple University ... The study reports that adenovirus type 5, a common vector for... (Science Daily)
It is already being used for gene therapy. (TAT is not involved in transmitting the HIV virus; it only aids the passage of other materials across the membranes of infected cells. (Science Daily)
AMSTERDAM, March 20 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, today announced that AMT's Supervisory Board has decided to propose Alexander Ribbink to be appointed to the Supervisory Board at its Annual General Meeting of shareholders on April 16, 2008 ... About Amsterdam Molecular Therapeutics AMT has a unique gene therapy platform that to date appears to circumvent many if not all of the obstacles that have... (PR Newswire)
17, 2001) Gene therapy may one day be used to halt or even prevent the overgrowth of blood vessels in the eye that blinds patients with macular degeneration and diabetic retinopathy, according to two recent. (Mar. (Science Daily)
So called gene therapy was hailed as a medical revolution two decades ago but progress has been slow, the successes have been hard to come by, and there have been a few deaths ... Now Sir Aaron Klug, a Nobel laureate working at the Medical Research Council's Laboratory of Molecular Biology in Cambridge, has developed a more efficient way to target genes, so gene therapy can be done with surgical precision ... Animal trials are already under way to use the same targetted gene therapy to reduce... (Telegraph.co.uk)
New developments and clinical trials breathe life back into gene therapy ... The past 15 years have been a roller coaster for gene therapy ... After being touted in the early 1990s as the medicine of the future, gene therapy left an 18-year-old dead and three others with leukemia; in July it was tied to the death of a 36-year-old Illinois woman undergoing treatment for rheumatoid arthritis, although further investigation cleared her therapy of the blame. (Scientific American)
18, 2005) Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary. (Nov. (Science Daily)
Tuesday, March 18, 2008. Published: Mar 18, 2008 12:30 AM Modified: Mar 18, 2008 02:42 AM. (News & Observer)
--- Gene therapy, in which a working gene is inserted into a cell to replace a faulty or absent gene, is a promising experimental technique for the prevention and treatment of disease ... This is different from traditional gene therapy, which is based on introducing new genes into the cell -- with its own advantages and problems because of that. (EurekAlert!)
The mechanism may also shed some light on why gene therapy experiments that use adenoviruses to deliver genes to humans have run into problems ... The new research could also help explain how a patient involved in a University of Pennsylvania gene therapy experiment that used an adenovirus to deliver the gene died. (EurekAlert!)
14, 2008) A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers ... The gene therapy developed at Duke would give liver cells the correct genetic code for manufacturing the enzyme ... The gene therapy replaced the missing enzyme in the liver to fully normal levels, and protected both mice and dogs with the disease from low blood glucose for up to a year. (Science Daily)
Physicians and scientists of Weill Cornell Medical College are engaged in cutting-edge research in areas such as stem cells, genetics and gene therapy, geriatrics, neuroscience, structural biology, cardiovascular medicine, transplantation medicine, infectious disease, obesity, cancer, psychiatry and public health -- and continue to delve ever deeper into the molecular basis of disease in an effort to unlock the mysteries of the human body in health and sickness ... Weill Cornell is the... (EurekAlert!)
Among the minnows, gene therapy specialist Oxford BioMedica is expected to report a strong cash position alongside today's full year results. Meanwhile, Anite is announcing an interim management statement on Monday and also hosting an analyst visit later in the day. (Forbes -- Markets)
They're throwing an arsenal of high-tech tools at the condition: genome studies, stem cell stimulation, gene therapy, a type of tissue engineering often called "hair cloning" and even robotics. The chance of much better treatments in time for your high school reunion. (San Francisco Chronicle)
Researchers attending the annual meeting of the American Academy of Orthopaedic Surgeons in San Francisco this week said they are slowly unlocking the doors to regenerative medicine using stem cells, gene therapy and tissue engineering. "It's the future of our specialty," said Dr. Thomas Einhorn, chairman of the Department of Orthopedic Surgery and professor of orthopedic surgery, biochemistry and biomedical engineering at Boston University. (MSNBC -- Health)
1, 2004) Self-organizing synthetic molecules originally used for gene therapy may have applications as templates and scaffolds for the production of inorganic materials. Using electrostatic interactions. (Science Daily)
In Australia, muck of this sort is expected to exist, as white Australians are, mostly, the "proud" inheritors of the genes of the worst Brit murderers and criminals of all other types and they have no escape from those rotten genes - at least until gene therapy comes in. They clearly show their background and breeding. (Sydney Morning Herald -- Sport)
Start On Way To Baldness Gene Therapy ... Start On Way To Baldness Gene Therapy ... Gersh Kuntzman, who wrote "Hair: Mankind's Historic Quest to End Baldness," explained to Roth that, "The silver bullet is always been gene therapy, because there is no drug that can grow hair on a bald man's head. It can't be done, because the follicles have already shrunk up. You can't reopen it. However, if you can figure out what genetic process constricts those follicles, then maybe you can change that... (CBS News -- Early Show)
When scientists used gene therapy to simulate a phosphate at this critical position, the rats brain cells didnt develop the Parkinson-like pathology that would normally occur ... Increasing their expression in brains afflicted with Parkinsons disease could possibly provide a gene therapy approach to the disease. (EurekAlert!)
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