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"Posted by: - 14 hours, 43 minutes agoDate: Tuesday January 15th, 2008, 5:40 pmPlease login to leave a comment Login Please login using your current username and password. If you have forgotten your details you can get a . Username Password Keep me signed in About the author: Matt Clarke Website Editor, Matt Clarke, writes the regular Interesting Imports column on rare and unusual fish in the UK aquarium trade. He's kept fish for over 20 years and holds a degree, two higher degrees and two... (Practical Fishkeeping)
Drug Addiction Genes Identified Jan 10, 2008
The researchers focused on four addictive substances -- cocaine, opiate, alcohol and nicotine -- and mapped out five main routes, or "molecular pathways", that lead to addiction, they wrote in the journal PLoS Computational Biology. Figuring out the molecular pathways of complex diseases is important as the genes and proteins involved are narrowed down. (MEDLINEplus)
* World News Quick Take Jan 9, 2008
The researchers focused on four addictive substances -- cocaine, opiates, alcohol and nicotine -- and mapped out five main routes, or "molecular pathways," that lead to addiction, they wrote in the journal PLoS Computational Biology. JAPAN. (Taipei Times, Taiwan -- World)
480 Genes That Control Human Cell Division Identified Jan 9, 2008
8, 2008) A team of U.S., Israeli and German scientists used computational biology techniques to discover 480 genes that play a role in human cell division and to identify more than 100 of those genes that have an abnormal pattern of activation in cancer cells ... "Some of the mutations may be caused by the non-cycling genes, rather than the other way around," said Bar-Joseph, an assistant professor of computer science and machine learning in the School of Computer Science and a member of... (Science Daily)
China experts identify drug addiction genes Jan 8, 2008
The researchers focused on four addictive substances -- cocaine, opiate, alcohol and nicotine -- and mapped out five main routes, or "molecular pathways," that lead to addiction, they wrote in the journal PLoS Computational Biology. Figuring out pathways are important in the study of complex diseases as they narrow down the genes and proteins involved. (Scientific American)
Assembling the jigsaw puzzle of drug addiction Jan 5, 2008
This novel paper appears in PLoS Computational Biology on January 4, 2008 ... This press release refers to an upcoming article in PLoS Computational Biology ... About PLoS Computational Biology. (EurekAlert!)
New Gene Prediction Method Capitalizes On Multiple Genomes Dec 21, 2007
Subjects covered include any aspect of molecular, cellular, organismal or population biology studied from a genomic perspective, as well as genomics, proteomics, bioinformatics, genomic methods (including structure prediction), computational biology, sequence analysis (including large-scale and cross-genome analyses), comparative biology and evolution. Genome Biology has an impact factor of 7. (Science Daily)
Why don't we get cancer all the time? Dec 20, 2007
Pepper and his colleagues published their paper, "Animal Cell Differentiation Patterns Suppress Somatic Evolution," in the current issue of PLoS Computational Biology. Pepper's co-authors are Kathleen Sprouffske of the University of Pennsylvania in Philadelphia and the Wistar Institute in Philadelphia and Carlo C. Maley of the Wistar Institute. (EurekAlert!)
Human Evolution May Be Spurred By Gene Loss Dec 15, 2007
Their findings appear in the December 14 issue of PLoS Computational Biology. This research was funded by the National Human Genome Research Institute, the National Institutes of Health, the National Cancer Institute, and the Howard Hughes Medical Institute. (Science Daily)
Bodily breakdown explained: How cell differentiation patterns suppress somatic evolution Dec 14, 2007
Fortunately it is normally controlled by a well-known pattern of ongoing cell differentiation in the mature tissues of animals, according to a new study published December 14 in PLoS Computational Biology ... This press release refers to an upcoming article in PLoS Computational Biology ... About PLoS Computational Biology. (EurekAlert!)
New computational technique can predict drug side effects Dec 12, 2007
Their study is currently available on line at PLoS Computational Biology. Conventional test methods screen compounds in animal studies in advance of human trials in the hope of identifying the side effects of promising therapeutics. (EurekAlert!)
Malaria Parasite In Patient Blood Finds Distinct Physiological States Dec 5, 2007
"This work illustrates the true power that comes from developing the right computational methods and applying them to important biomedical problems," said co-senior author Jill Mesirov, director of Computational Biology and Bioinformatics at the Broad Institute of MIT and Harvard. "Even more importantly, it reflects scientific research at its best -- a global effort that brings together clinicians and researchers with diverse expertise, working directly with patients in areas hardest hit by... (Science Daily)
Gene Research Has Implications For Huntington's Disease Nov 26, 2007
These findings were recently presented in PLoS Computational Biology. Adapted from materials provided by. (Science Daily)
Evolutionary Comparison Finds New Human Genes Nov 24, 2007
The research is reported by Adam Siepel, Cornell assistant professor of biological statistics and computational biology, Cornell postdoctoral researcher Brona Brejova and colleagues at several other institutions in the online version of the journal Genome Research, and it will appear in the December print edition. The complete human genome was sequenced several years ago, but that simply means that the order of the 3 billion or so chemical units, called bases, that make up the genetic code is... (Science Daily)
Rebuilding the evolutionary history of HIV-1 unravels a complex loop Nov 24, 2007
An essential component of the human immunodeficiency virus (HIV-1) molecular machinery responsible for infecting cells consists of functionally-specialized layers, according to a study by investigators at the University of California San Diego (UCSD) Antiviral Research Center (AVRC), published November 23 in PLoS Computational Biology ... This press release refers to an upcoming article in PLoS Computational Biology ... About PLoS Computational Biology. (EurekAlert!)
Are There Rearrangement Hot Spots In The Human Genome? Nov 14, 2007
The study, published on November 9 in PLoS Computational Biology, holds that there are indeed rearrangement hotspots in the human genome. See also. (Science Daily)
Role Of Hemoglobin In Oxygen Transport Modeled At Atomic Level Nov 13, 2007
The investigation led by V;ctor Guallar, ICREA researcher with the Life Sciences department of the Barcelona Supecomputing Center (BSC) and group leader of the Joint Computational Biology Programme between the Institute for Research in Biomedicine (IRB Barcelona) and the BSC, has allowed the definition at atomic level of the mechanism that regulates the exchange of lung oxygen to hemoglobin and from hemoglobin to tissue. More than a hundred years of study have led to the knowledge that... (Science Daily)
Genome study charts genetic landscape of lung cancer Nov 5, 2007
11Departments of Medicine, Surgery, Pathology, and Computational Biology, 12Human Oncology and Pathogenesis Program, 13Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA 10065. 14Section of Thoracic Surgery, Department of Surgery and 15Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA 48109. (EurekAlert!)
Unravelling The Secrets Of Cancer Cells Oct 30, 2007
Professor Soto, Professor of Anatomy and Cellular Biology at Tufts, is working alongside UU s Professor Vyvyan Howard, Professor of Bio-Imaging, Dr George McKerr, Director of the Centre for Advanced Imaging and Dr Kurt Saetzler, a lecturer in computational biology. Professor Soto says: We think the 3-D model will allow us to study cancer as it occurs. (Science Daily)
DNA pioneer retires after comment on blacks Oct 27, 2007 Emergence of recombinant forms of HIV: dynamics and scaling Oct 26, 2007 CMU given big grant for Life Sciences Oct 23, 2007 Matching Pathogens To Their Antibodies: Could Lead To HIV Vaccine Oct 16, 2007 Genome of Green Alga Unraveled Oct 15, 2007 Genomic technologies to identify toxic chemicals should be developed Oct 10, 2007 Stanley Hall dedication heralds new era of bioscience innovation UCB, Sep. 26 Sep 28, 2007 Postdoctoral Scientist Positions Sep 25, 2007 MIT model could improve some drugs' effectiveness Sep 24, 2007 Understanding Malarial Parasites Sep 21, 2007 Brain's memory capacity less than thought Sep 15, 2007 A Balanced Memory Network Sep 12, 2007 Face-scan can spot genetic illnesses Sep 12, 2007 The Emergence Of A Sense Of Orientation Sep 1, 2007 Math Model For Circadian Rhythm Created Aug 31, 2007 Longer Life? 'Longevity' Genes Protect Very Old People From The Bad Genes' Harmful Effects Aug 25, 2007 Online videos catch on Aug 23, 2007 Birds Learn To Fly With A Little Help From Their Ancestors Aug 21, 2007 Today's White Rice Is Mutation Spread By Early Farmers Aug 21, 2007 Program that melds life sciences, computers awarded $5.6 million UCI, Aug. 16 Aug 17, 2007 Quantum Analog Of Ulam's Conjecture Can Guide Molecules, Reactions Aug 15, 2007 Bacteria does not hasten death in fruit flies Aug 11, 2007 The American path to jihad Aug 10, 2007 Regulators evolve faster than genes Aug 10, 2007 Bacteria May Not Hasten Death Aug 9, 2007 Research Positions Aug 9, 2007 Weed gave up sex long ago Aug 8, 2007 Where Broken DNA Is Repaired Aug 7, 2007 UCI awarded $14.4 million to support systems biology center UCI, Aug. 01 Aug 2, 2007 How Would The Avian Influenza Virus Be Transmitted In Human Households? Jul 28, 2007 Nicotine rush hinges on sugar in neurons Jul 23, 2007 Microsoft Reveals Research Roadmap Jul 18, 2007 New Treatment Model For HIV Developed Jul 16, 2007 A walking robot goes mountaineering Jul 14, 2007 Scientists say computers may replace drugs Jul 13, 2007 Walking robot offers clues to human movement Jul 13, 2007 Robot tackles mystery of walking Jul 13, 2007 A First-principles Model Of Early Evolution Jul 13, 2007 Evidence Of Very Recent Human Adaptation: Up To 10 Percent Of Human Genome May Have Changed Jul 13, 2007 New spin-off offers enterprise solution to open source statistical software Jun 22, 2007 PLoS journal retracts phylogenetics paper Jun 19, 2007 Report calls for new directions, innovative approaches in testing chemicals for toxicity to humans Jun 13, 2007 State funds $2.71 million stem cell research facility at UCSC UCSC, Jun. 06 Jun 7, 2007 Simulations Unravel Outer Membrane Transport Mechanism Jun 6, 2007 RPI eyes supercomputer pact Jun 1, 2007 In new statistical approach, data decide model May 24, 2007 'Star Trek'-type Scanning May Reveal Genetic Activity Of Tumors, Study Shows May 23, 2007 Executable Biology: Computer Science Sheds Light On Animal Development May 19, 2007 Insignia: A New Way To Identify Viruses And Bacteria May 19, 2007 Role Of Noise In Neurons May 9, 2007 New Technique Will Produce A Better Chromosome Map May 9, 2007 US Control Strategies May Make Flu Epidemics Worse, Study Shows May 8, 2007 Vaccine to cope with viral diversity in HIV Apr 27, 2007 U. of Md. creates institute to study microorganisms Apr 26, 2007 Bird Flu Genome Study Shows New Strains, Western Spread Apr 20, 2007 Massachusetts General Hospital reaps $284m drug sale windfall Apr 19, 2007 Map predicting spread of avian flu Apr 19, 2007 What makes humans tick? Maybe a monkey knows Apr 13, 2007 Pandemic Fears? Try Growing Flu Vaccine Fast In Insect Cells (Not Eggs) Apr 12, 2007 Sites aimed at preteens gaining in popularity Apr 9, 2007 'Tweens' tap into the Web Apr 6, 2007 How DNA sequence divides chihuahua and great dane Apr 6, 2007 Transfusion expert urges wider use of filtered blood Apr 4, 2007 Officiating bias, influenced by crowds, affects home field advantage Apr 4, 2007 NIH neuroscience microarray consortium launches high-throughput genotyping services Mar 29, 2007
Under Watson's direction, the laboratory has investigated the genetic causes of cancer, plant biology, neuroscience and computational biology, according to a statement the lab issued Thursday about Watson's retirement. In his own statement, which amounted to a professional biography, Watson described coming to the lab 49 years ago to give his first course, and he noted the contributions to scientific understanding that the research center has made since then. (San Francisco Chronicle)
DNA pioneer steps down as lab chief after racial remark Oct 26, 2007
After he left Harvard to direct the laboratory, Watson transformed it from a small facility into a world-class institution prominent in research on cancer, plant biology, neuroscience, and computational biology, the board said in announcing his retirement. Bruce Stillman, who succeeded him as president, said that Watson had created an unparalleled research environment at the lab. (Boston Globe)
In a study publishing in PLoS Computational Biology on October 26, 2007, researchers Suryavanshi and Dixit from the Indian Institute of Science, Bangalore, India present a new model of HIV dynamics that provides a detailed account of the emergence and growth of recombinant forms of HIV following infection with diverse viral genomes ... PLEASE MENTION THE OPEN ACCESS JOURNAL PLoS COMPUTATIONAL BIOLOGY () AS THE SOURCE FOR THIS ARTICLE AND PROVIDE A LINK TO THE FREELY AVAILABLE TEXT. THANK YOU.... (EurekAlert!)
The latest gift will establish a Life Sciences Competitiveness Fund to support faculty, new labs and a Presidential Scholars Fund for graduate students focusing on life science fields, such as computational biology, medical robotics and biomedical engineering. "The world is seeing phenomenal breakthroughs in biological sciences, and the implications of that for human health and business are tremendous," said CMU President Jared Cohon. (Pittsburgh Post-Gazette, PA)
A new study by David Heckerman and colleagues from Massachusetts General Hospital, publishing in PLoS Computational Biology, has come up with a way to match pathogens to their antibodies. At the core of the human immune response is the train-to-kill mechanism in which specialized immune cells are sensitized to recognize small peptides from foreign pathogens (e. (Science Daily)
"The Chlamy genome is like a green time capsule that affords a view into the complex core machinery that gave rise to today's energy-capturing and oxygen-producing chloroplasts," said Daniel Rokhsar, DOE JGI Computational Biology Program head, who co-led the effort with DOE JGI Computational Scientist Simon Prochnik, Arthur Grossman of the Carnegie Institution and Stanford University, and Sabeeha Merchant of UCLA.. Page 1. (MedIndia)
John Quackenbush Professor Department of Biostatistics and Computational Biology Dana-Farber Institute, and Professor Department of Biostatistics Harvard School of Public Health Boston. Kenneth S. Ramos Professor and Chair Department of Biochemistry and Molecular Biology University of Louisville Health Sciences Center, and Director Center for Genetics and Molecular Medicine Louisville, Ky. (EurekAlert!)
And computational biology, which incorporates the techniques of computer science, mathematics and statistics into the field of biology, was critical to the successful sequencing of the human genome. "Making progress toward solving the grand challenges of biological sciences pushes the limits of each discipline," he said. (University of California Newswire, CA)
APPLIED COMPUTATIONAL BIOLOGY AND BIOINFORMATICS GROUP Ref: PI/07/20A position is available for a computational biologist to develop novel approaches for the analysis of high throughput genomic data. We are an interdisciplinary team that brings together skills in computer science, biology and mathematics, and are focused on the development and application of bioinformatics tools to support the interpretation of complex datasets (see, for example, ). (Nature News Service)
Making drugs out of huge, complicated molecules like antibodies is incredibly hard, said Janna Wehrle, who oversees computational biology grants at the National Institute of General Medical Sciences, which partially supported the research. Dr. (EurekAlert!)
In a new study publishing in PLoS Computational Biology on September 14, 2007, Dr. Tatu and colleagues from the Indian Institute of Science have constructed a chaperone interaction network for the parasite which provides, for the first time, a rational basis for the anti-malarial effect of known drugs and highlights new proteins that can potentially be used in the fight against malaria ... Note: This story has been adapted from a news release issued by PLoS Computational Biology. (Science Daily)
Latham and his colleague's findings are detailed online in the journal PLoS Computational Biology. Noisy neurons Neurons produce electrical signals that travel through each cell's 10,000-or-so each connected to another neuron to form a "network" of communicating cells. (MSNBC -- Health)
In a study publishing in PLoS Computational Biology on September 7, 2007, they show that for realistic networks of spiking neurons, the number of memories is not proportional to the number of neurons, it's proportional to the number of connections per neurons -- at most about 10,000. Moreover, they provided evidence that the constant of proportionality is small, not more than a few percent, and they eliminated one of theorists' favorite tricks -- reducing the number of neurons involved in any... (Science Daily)
Professor Peter Hammond, a specialist in computational biology at the Institute of Child Health at University College London (UCL), said yesterday it could revolutionise diagnosis and treatment of conditions affecting tens of thousands of people. "Some conditions are very obvious; for example, you can spot a kid with Down's Syndrome a mile away, but there are over 700 genetic conditions that involve unusual and often very subtle facial characteristics," he said. (Scotsman)
The work will be published on August 31, 2007, in the scientific journal PLoS Computational Biology. CITATION: Franzius M, Sprekeler H, Wiskott L (2007) Slowness and sparseness lead to place, head-direction, and spatial-view cells. (Science Daily)
In the August online edition of Public Library of Science (PLOS) Computational Biology, Cornell biomolecular engineer Kelvin Lee, in collaboration with graduate student Robert S. Kuczenski, Kevin C. Hong '05 and Jordi Garcia-Ojalvo of Universitat Politecnica de Catalunya, Spain, hypothesize that the accepted model of circadian rhythmicity may be missing a key link, based on a mathematical model of what happens during the sleeping/waking cycle in fruit flies. "We didn't discover any new proteins... (Science Daily)
We hypothesized that people living to 100 and beyond must be buffered by genes that interact with disease-causing genes to negate their effects, says Dr. Aviv Bergman, a professor in the departments of pathology and neuroscience at Einstein and senior author of the study, which appears in the August 31 issue of PLoS Computational Biology. To test this hypothesis, Dr. Bergman and his colleagues examined individuals enrolled in Einstein s Longevity Genes Project, initiated in 1998 to investigate... (Science Daily)
According to its creator, of the University of California, San Diego, and founding Editor-in-Chief of PLoS Computational Biology, the goal of SciVee is to help researchers quickly digest new scientific literature. Initially, SciVee will link just to papers published by PLoS, but if the site becomes a useful resource for scientists, Bourne would like to make arrangements with other publishers to include all papers in PubMed. (The Scientist)
Results are reported in: Stone JV, "Distributed Representations Accelerate Evolution of Adaptive Behaviours", PLoS Computational Biology, 2007 (in press). Note: This story has been adapted from a news release issued by University of Sheffield. (Science Daily)
Scott Williamson and Carlos Bustamante, both researchers in Cornell's Department of Biological Statistics and Computational Biology, were also co-authors on this paper. The research was supported by the Plant Genome Program of the National Science Foundation, the Generation Challenge Program, Chengbuk National University and Korea's National Institute of Agricultural Biotechnology. (Science Daily)
The field of computational biology is booming at UC Irvine. Earlier this month, its Center for Complex Biological Systems received a $14. (University of California Newswire, CA)
"Using photons, we can harness chaotic motion to control chemical reactions and to move quantum objects, such as nanoclusters, molecules and buckyballs," said Martin Gruebele, a William H. and Janet Lycan Professor of Chemistry, and the director of the Center for Biophysics and Computational Biology at Illinois. Gruebele and co-author Peter Wolynes, a professor of chemistry and biochemistry at the University of California, describe their work in a paper accepted for publication in Physical... (Science Daily)
Led by John Tower, Associate professor of molecular and computational biology at the University of Southern California, a team of researchers compared fruit flies to ones kept in an axenic (bacteria-free) environment. It was found that flies scrubbed clean of bacteria did not outlive their grubby siblings. (DailyIndia.com)
After returning to the US, he received a PhD in computational biology from George Mason University in Virginia. In addition to his academic pursuits, Timimi was an Islamic teacher in the northern Virginia area. (Asia Times Online)
A.M. Moses et al., "Large-scale turnover of functional transcription factor binding sites in Drosophila," PLoS Computational Biology, October 2006. Ernest Fraenkel Leonid Kruglyak L. Kruglyak and D.L. Stern, "An embarrassment of switches," Science, August 10, 2007. (The Scientist)
A research team led by John Tower, associate professor of molecular and computational biology at USC, compared normal fruit flies to ones kept in an axenic (bacteria-free) environment. "The surprise was that the flies grown under axenic conditions and the normal flies had the same life span," Tower said. (Science Daily)
nar/009; Computational Biology (nar/010); Animal Cell Technology (nar/011); Functional analysis of transcription regulators in plants (nar/012); Single-particle and single-molecule analysis in biological systems (nar/013); Chemistry of organic and inorganic biologically important compounds (nar/014); Cell signaling (nar/017); Host- bacterial pathogen interactions (nar/018). Suitable qualified candidates from other areas in Chemistry, Life Sciences and associated technologies could be also... (Nature News Service)
The mustard-like plant Arabidopsis thaliana lost interest in sex and started self-pollinating at least a million years ago, said plant geneticists led by Magnus Nordborg, associate professor of molecular and computational biology at the University of Southern California ... We can rule out a very recent change to self-fertilization, said Chris Toomajian, USC research associate in molecular and computational biology and co-author of two new papers on A. thaliana in Science Express and Nature... (EurekAlert!)
"Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains," by Sylvain V. Costes, Artem Ponomarev, James L. Chen, David Nguyen, Francis A. Cucinotta, and Mary-Helen Barcellos-Hoff, appears online in the August 2007 PLoS Computational Biology, (volume 3, issue 8). Note: This story has been adapted from a news release issued by DOE/Lawrence Berkeley National Laboratory. (Science Daily)
This center also developed a new doctoral program in mathematical and computational biology in which students with backgrounds ranging from math, physics, chemistry, engineering, computer science and biology can train in systems biology. The first class of students has been admitted for fall 2007. (University of California Newswire, CA)
In a study published in PLoS Computational Biology, the authors from the Netherlands and the United Kingdom have used data from a small but well-defined study of H7N7 avian influenza virus transmission in human households to estimate this transmissibility in humans living in close contact ... Note: This story has been adapted from a news release issued by PLoS Computational Biology. (Science Daily)
When nicotine binds to a neuron, how does the cell know to send the signal that announces a smokers high" As with other questions involving good sensations, the answer appears to be sugar. A University of Southern California study appearing with a commentary in Nature Neuroscience online proposes a role for sugar as the hinge that opens a gate in the cell membrane and brings news of nicotines arrival. Structural biologist Raymond Stevens of The Scripps Research Institute, who was not involved... (EurekAlert!)
In order to further its goals, MSR has set up a network of 11 academic research centers across the globe to pursue research into a diverse set of technologies and goals, ranging from computational biology to collaboration techniques in the classroom to pen-based computing, Sailesh Chutani, director of External Research and Programs at MSR, told the gathering during Monday's opening session. Microsoft's research division has also issued a series of requests for proposals (RFP) in order to fund... (CIO Information Network)
In a study publishing July 13, 2007 in PLoS Computational Biology, clinical responses to antiretroviral drug therapy are simulated for the first time, and the model is then applied to IM therapy. Marcel Curlin, Shyamala Iyer, and John Mittler, from the University of Washington, find that IM is expected to be successful beyond three years and that six to ten months of induction therapy should achieve durable suppression of HIV and maximize the possibility of eradicating viruses resistant to the... (Science Daily)
In their study, publishing in PLoS Computational Biology July 13, 2007, scientists around Florentin Wrgtter, Bernstein Center for Computational Neuroscience at the University of Gttingen, have simulated the neuronal principles that form the basis of this adaptivity in a walking robot. "RunBot", as it is called, lives up to its name it holds the world record in speed walking for dynamic machines. (Hindu)
" Professor Harel demonstrated a computer model of a C.elegans a 1mm-long worm of interest to scientists because it had various systems in common with humans, despite having a relatively small number of cells which helps to explain why certain cells in the worm developed particular functions. Another model drew on the work of more than 400 research papers to show the interaction of T-cells a type of white blood cell which plays a role in the immune system that had become cancerous. "This work,... (Times Online)
Woergoetter, who published his findings in the journal Computational Biology, compared the process with the way a child learns to walk. He said just like humans, RunBot leans forward slightly and uses shorter steps to navigate uphill. (Scientific American)
The latest findings of the robot research study are presented in the Public Library of Science Computational Biology journal. Four other scientists - Poramate Manoonpong, Tao Geng, Tomas Kulvicius and Bernd Porr - are also involved in the project, which has been running for the last four years. (BBC News -- Science)
In a study publishing in PLoS Computational Biology, Shakhnovich et al present a new model of early biological evolution -- the first that directly relates the fitness of a population of evolving model organisms to the properties of their proteins. Key to understanding biological evolution is an important, but elusive, connection, known as the genotype-phenotype relationship, which translates the survival of entire organisms into microscopic selection for particular advantageous genes, or... (Science Daily)
"We undertook a very careful study of genetic differences within and among major human groups, and aimed to explain why certain parts of the genome differed," said Scott Williamson, the study's lead author and a Cornell assistant professor of biological statistics and computational biology ... "It is important to emphasize that the research does not state that one group is more evolved or better adapted than another," said co-author Carlos Bustamante, a Cornell assistant professor of biological... (Science Daily)
D., the companys founder, an associate professor of Biostatistics and Computational Biology, and co-director of computational software development at the University of Rochesters Center for Biodefense Immune Modeling. R is an exceptionally useful system with tremendous capabilities and has been widely adopted by academic and research statisticians. (EurekAlert! -- Business News)
PLoS Computational Biology is retracting a published in March that claimed that metrics used to measure the accuracy of phylogenetic trees don't work ... "It is as important to PLoS Computational Biology as it is to Dr. Hall to correct the record," , a managing editor at the journal, told The Scientist ... "PLoS Computational Biology initiated the formal retraction process immediately upon Dr. Hall's first contact," she said in an Email. (The Scientist)
MELVIN E. ANDERSEN Director Computational Biology Division The Hamner Institutes for Health Sciences Research Triangle Park, N.C.. HENRY A. ANDERSON Chief Medical Officer and State Epidemiologist for Occupational and Environmental Health Wisconsin Division of Public Health, and Adjunct Professor of Population Health University of Wisconsin Medical School Madison. (EurekAlert! -- Business News)
Drawing on their broad range of expertise in development, genetics, genomics, and molecular, cell and computational biology, these researchers are using interdisciplinary approaches to tackle problems concerning how genes are regulated in human embryonic stem cells, and how this regulation influences their ability to both self-renew and differentiate into specific cellular subtypes. Defining and ultimately controlling this process is an essential step in designing medical therapies based on the... (University of California Newswire, CA)
Tajkhorshid is also a professor of pharmacology in the College of Medicine and an affiliate of the Beckman Institute and the Center for Biophysics and Computational Biology in the College of Liberal Arts and Sciences. Funding for the research was provided by the National Institute of General Medical Sciences at the National Institutes of Health. (Science Daily)
The computers, which combined could process more than 200 trillion computations a second, would do computational biology to help design new lifesaving drugs and therapies. John Kolb, chief information officer at RPI, said the Troy college has been discussing the plan with Stony Brook for about a year. (Albany Times Union)
In computational biology, for example, Ma and colleagues have used the technique to discover unique patterns of gene expression in fruit flies and roundworms, to study differential gene expression of the retinal development in zebra fish, and to explore the effect of histone modifications on gene transcription rates in yeast. . (EurekAlert!)
To increase the research team's expertise in the areas of genomics and computational biology, Kuo brought in Chang and the paper's lead author, Eran Segal, PhD, in 2004. Chang had been using the gene activity patterns of microarrays to predict cancer outcome. (Science Daily)
The novel in silico model is described in the open-access journal PLoS Computational Biology. During C. elegans development, uncommitted precursor cells differentiate into two distinct cell types in response to a series of complex biochemical signaling events. (Science Daily)
They describe this new computational system, called Insignia, and the results of its successful application on 46 Vibrio cholerae strains this week in the Open Access journal PLoS Computational Biology. Insignia uses highly efficient algorithms to compare known bacterial and viral genomes against each other and to background genomes including plants, animals, and humans. (Science Daily)
Using detailed models of rodent and squid axons and stochastic simulations, the authors performed experiments, now published in PLoS Computational Biology, which took several months to simulate a few milliseconds of real time in the brain. They show how conduction along such thin axons is affected by the probabilistic nature of voltage-gated ion channels (channel noise). (Science Daily)
Belmont is in the U. of I. Institute for Genomic Biology and the Center for Biophysics and Computational Biology. Their work appears online May 6 in advance of publication in the journal Nature Methods. (Science Daily)
In a report to be published in the peer-reviewed journal PLoS Computational Biology and currently available online, Sally Blower, a professor at the Semel Institute for Neuroscience and Human Behavior at UCLA, and Romulus Breban and Raffaele Vardavas, postdoctoral fellows in Blower's research group, used novel mathematical modeling techniques to predict that current health policy -- based on voluntary vaccinations -- is not adequate to control severe flu epidemics and pandemics unless... (Science Daily)
PLEASE MENTION THE OPEN-ACCESS JOURNAL PLoS COMPUTATIONAL BIOLOGY () AS THE SOURCE FOR THIS ARTICLE AND PROVIDE A LINK TO THE FREELY-AVAILABLE TEXT. THANK YOU. ... This press release refers to an upcoming article in PLoS Computational Biology ... About PLoS Computational Biology. (EurekAlert!)
Researchers at the institute will use advances in computational biology, for example, to analyze and understand the complex genetic controls that contribute to microorganisms causing disease. The institute will be housed in the university's new biosciences research building, scheduled to open this summer. (Washington Business Journal, DC)
"This is the first time anyone's looked at all of the H5N1 genomes in the west," said Steven Salzberg, the study's lead author and director of the University of Maryland Center for Bioinformatics and Computational Biology. "Until now, the studies have been primarily on samples from the Far East . Our study shows that the virus is spreading west, and that there have been three separate introductions of H5N1 in Europe, the Middle East and Africa.". (Science Daily)
Slavin said the $213 million will be divided evenly between Seed's department, molecular biology; the hospital's center for computational biology; and its central coffers. Christopher Rowland can be reached at. (Boston Globe)
The paper, published in the Open Access journal PLoS Computational Biology, arrives at these conclusions through a computational (or mathematical) modeling method, an approach which has already proved its worth in the analysis of infectious diseases such as the 2001 foot-and-mouth outbreak in the UK. The method can estimate the key parameters which determine the spread of highly transmissible animal diseases between farms ... This press release refers to an upcoming article in PLoS Computational... (EurekAlert!)
"What we have done is lay the foundation for understanding the biology for AIDS progression," said Carlos Bustamante, an assistant professor of computational biology at Cornell University who helped perform the analysis. 000030CD MORE STORIES IN Top stories. (Houston Chronicle)
D., associate professor of Biostatistics; and Jeanne Holden-Wiltse, M.P.H., research associate in Biostatistics and Computational Biology. Also participating were nurse practitioner Carrie Nolan and nurses Diane O'Brien, Pat Smith, and Mary Lou Werthman. (Science Daily)
He also is a professor of computational biology at the University of Texas, San Antonio, and said his site is more about education than anything else. It teaches kids about nutrition, gives them science lessons and throws in a little math. (Chicago Tribune)
He's also a professor of computational biology at the University of Texas, San Antonio, and says his site is more about education than anything else. It teaches kids about nutrition, gives them science lessons and throws in a little math for good measure. (Sun-Sentinel.com)
"It is staggering to think that so many of the small dog breeds came about through selection on the same mutation in the same gene," said Carlos Bustamante, a professor of computational biology at Cornell University and one of the authors of the paper in Science. "These results suggest that while there are invariably differences among breeds ... IGF1 has played an important role in the evolution of many small breeds by being a gene that consistently affects body size.". (Guardian Unlimited -- UK)
Hongwei Zhao, Hongkun Wang and Susan Messing of the UR Department of Biostatistics and Computational Biology. . (EurekAlert!)
Adam Boyko is a post-doctoral researcher in the Department of Biological Statistics and Computational Biology at Cornell University, and Mark Boyko was a student at the New York University School of Law at the time of the study. . (EurekAlert!)
TGen is focused on personalized medicine and plans to accomplish its goals through robust and disease-focused research programs and its state-of-the-art bioinformatics and computational biology facilities ... IGSP activities are organized through five research centers: the Center for Genome Technology, the Center for Human Genetics, the Center for Human Disease Models, the Center for Bioinformatics and Computational Biology and the Center for Genome Ethics, Law and Policy. (EurekAlert! -- Business News)
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