A Very Short War Oct 9, 2009
The Ron Paul movement may have succeeded in raising our profile one tiny notch: Instead of being non-entities, we paleos might get some opportunistic pandering. Its a start, but a long way from a takeover. (The American Conservative)
Stem Cells Which 'Fool Immune System' May Provide Vaccination For Cancer Oct 9, 2009
8, 2009) Scientists from the United States and China have revealed the potential for human stem cells to provide a vaccination against colon cancer, reports a study published in Stem Cells. This discovery, led by experts in immunology, Dr. Bei Liu and Dr. Zihai Li, builds upon a century old theory that immunizing with embryonic materials may generate an anti-tumour response. (Science Daily)
New Chemo Cocktail Blocks Breast Cancer Like A Strong Fence Oct 8, 2009
This discovery indicates the mechanism by which inappropriate expression of the notch pathway may. (Dec. (Science Daily)
Merkel Cell Originates From Skin, Not The Neural Crest Oct 8, 2009
5, 2007) Defects in the heart and/or blood vessels (cardiovascular defects) in both humans and mice can result from mutations in any one of a number of genes encoding proteins that are part of the Notch. (May 21, 2008) For a fertilized egg to develop into an embryo a mass of identical cells must be directed to become a large number of distinct cell types with different functions and then these cells must be. (Science Daily)
Why do you think men in power have affairs? Oct 5, 2009
I value my integrity more than another notch on the pistol. You can't cheat and claim to be an honest man. (Columbus Telegram, NE)
Nanoresearchers Challenge Dogma In Protein Transportation In Cells Oct 1, 2009
5, 2007) Defects in the heart and/or blood vessels (cardiovascular defects) in both humans and mice can result from mutations in any one of a number of genes encoding proteins that are part of the Notch. (Apr. (Science Daily)
Scientists discover clues to what makes human muscle age Sep 30, 2009
They learned from previous studies that adult muscle stem cells have a receptor called Notch, which triggers growth when activated ... The researchers said that aging in mice is associated in part with the progressive decline of Notch and increased levels of TGF-beta, ultimately blocking the stem cells' capacity to effectively rebuild the body ... This study revealed that the same pathways are at play in human muscle, but also showed for the first time that mitogen-activated protein (MAP) kinase... (EurekAlert!)
The Chase Has Changed Sep 30, 2009
Dream take it up a notch to 50, I ve met some very immature 40ish men. THE INFAMOUS DK. (Atlanta Journal-Constitution -- Living)
Why are doctors overbooking? Sep 26, 2009
marygb wrote on Sep 23, 2009 5:15 AM:" Folks: Eisenhower medical facilities are rated top notch nationwide and doctors want to work there, but..WE WAIT.&.WAIT.&.WAIT.&.WAIT, each and every time! EVERYONE WAITS..I don't care how much jewelry is dripping off of someone's wrist or how many jags, beemers, R&Rs are parked outside. The majority of these physicians specialize, have lots of staff, yet..patients..WAIT, WAIT.. so please don't feel like the Lone Rangers in the Imperial Valley, this is... (El Centro Imperial Valley Press, CA)
Justice Ginsburg at Washington Hospital... Developing... Sep 25, 2009
to do without top notch "American Healthcare". I'm still waiting for one of these elites to jet off to Canada, Great Britian or Cuba for their healthcare. (The Drudge Report)
Palo Alto labor union may call strike Sep 24, 2009
" That is not a benefit of an SEIU employee, that is a benefit of a manager. In fact, that is something the SEIU union has a problem with, and thinks should be changed. The amount of misinformation I'm reading on this thread is truly amazing. Posted by A Noun Ea Mus, a resident of the Professorville neighborhood, on Aug 29, 2009 at 2:55 pmTo Lineman, I hope you and the other city workers don't assume that the people posting here represent some cross section of the Palo Alto citizenry. It pains... (Palo Alto Online, CA)
Mandan to review waterfront noise petition Sep 15, 2009
cc wrote on Sep 14, 2009 8:39 PM:" this is the first I've heard of a petition but living in the area I was suprised at the total lack of concern about this exact thing happening. the owners must be so out of touch with reality. There is no attempt to muffle the noise at "the drink". this is the case during the week as well as w-ends and although I am against regs and petitions sometimes people need to be challenged to be more reasonable. if anyone thinks this is simply a bunch of rich old people... (Bismarck Tribune, ND)
Prevent defense nearly prevented a win Sep 14, 2009
A.J. Green emulated the departed MoMass with the way he was able to shake off that fumble on Georgias second play and come back to notch six catches for 86 yards, including a clutch touchdown where he went up high for the ball between two defenders in the back of the end zone and managed to stay in bounds. Hes a big weapon and its easy to understand how Mike Bobo and Joe Cox are tempted to rely on the pass, but Georgia again left tailback Richard Samuel out of the mix for too long in... (Atlanta Journal-Constitution -- Sports)
Nesbitt must improve Sep 12, 2009
All of a sudden Miami is top notch because they beat FSU, well who is FSU. Neither team had much D in that game. Again, I try to stay out of the past when possible. (Atlanta Journal-Constitution -- Sports)
Cell Discovery Opens New Chapter In Drug Development Sep 9, 2009
8, 2009) British scientists have uncovered new details about how the cells in our bodies communicate with each other and their environment: findings that are of fundamental importance to human biology. Cells talk to each other through a complex process called signaling. (Science Daily)
Georgia must get better play at quarterback Sep 8, 2009
It goes either like 06 where we broke in a fresh QB and struggle the first half or it goes like 07 where we really pick it up a notch. Either way what you will see is improvement. (Atlanta Journal-Constitution -- Sports)
Vacancy For Lecturers: Professors and Professor Drs Only, Please Sep 7, 2009
From August last year when the directive was activated, some 30 teachers have been appointed assistant lecturers, a position which isnt particularly lower than a lecturer, except that a full lecturer has a slightly higher salary notch. In addition, the University has made available considerable amount of money for research towards promotion and further education of lecturers. (Ghana Web, Ghana)
On Track alternative-learning program up and running Sep 6, 2009
ontheinside wrote on Sep 5, 2009 11:34 AM:" The intellectual bar just got bumped down one notch! Can't learn here? Go over here and we'll hold your hand. Don't want to try hard? That's okay, someone has a program all worked out for ya! Woke up and decided not to apply yourself to anything mentally or physically? Hey, no sweat bud, the gub-ment will do it for you. Oh, the state of our union is weak, so very weak. ". Daedelus wrote on Sep 5, 2009 12:54 PM:" It says a lot about this community when... (Longview Daily News, WA)
Tech wins, but pugnacious Paul plainly isnt pleased Sep 6, 2009
I am not a UGA fan, but at least they opened up with a top notch team. -so you run the risk of loseing. (Atlanta Journal-Constitution -- Sports)
MINOR/The 2011 GOP roadmap Sep 3, 2009
Recent events seem to have scrambled the original Republican scheme, moving Reeves up a notch as a possible challenger against Bryant rather than Hewes. It has been known for sometime that Bryant was not exactly the guy Barbour was looking for as his successor, despite the fact Bryant has loyally carried out Barbour's legislative agenda. (Philadelphia Neshoba Democrat, MS)
Obituaries » Sep 1, 2009
Customer service was top notch. For 17 years, Gates Nichols played steel guitar for Confederate Railroad even though he preferred the bass. (Atlanta Journal-Constitution -- Metro)
Read the story Aug 31, 2009
I'm Amazed at all these "Conservatives"Thinking they are less safeMore B S fearAs I see it weve had the same top notch MilitaryUnder both GOP and the DemsAnd I don't think their any less CompetentUnder either party. Having said that The CIA will ContinueDoing clandestine operationsI think the ones who relly fear are CheneyAnd his brood of War CriminalsWho outed Valerie PlameAnd used the CIA to justify phony intelligenceSo his compan halliburton, and othersCould make Billions off an unnecessary... (CBS News -- Evening News)
Health care reform needed Aug 25, 2009
In fact, my experience is that the ones working for the government tend to be a notch above the rest ... In fact, my experience is that the ones working for the government tend to be a notch above the rest. (Logan Herald Journal, UT)
Protesters take to street again opposing Giffords Aug 24, 2009
Term Limits wrote on Aug 23, 2009 2:43 PM:" All Congressional and Senate representatives should only be allowed one term unless they when a super majority of 75% of their electorate choose then in re-election. Others should be able to contribute as a leaders in the political realm. Furthermore, when you are no longer a rep stop receiving all of those perks like life long government health care that is top notch. Pay for it yourself. With no term limits you become thieves in the eyes of your... (Sierra Vista Herald, AZ)
Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells Aug 17, 2009
Studies have provided important findings about the roles of Notch signaling in neural development ... We here investigated the role of Notch signaling with the hESC-derived NESs ... We found that Notch signaling, which maintains stem cell characteristics of in-vivo-derived neuroprogenitors, is active in these hESC-derived NESs, similar to their in-vivo counterpart. (BioMed Central)
Herding Squirrels: The package deal Aug 11, 2009
First the whole way, until those last 20 feet, when the true winner, inspired my crazy-fast pace, would kick it up a notch because he refused to lose to a girl ... First the whole way, until those last 20 feet, when the true winner, inspired my crazy-fast pace, would kick it up a notch because he refused to lose to a girl. (Fresno Bee -- Lifestyle)
Could this be the bottom of the Great Recession? Aug 9, 2009
Let me punch this up a notch and see if you can read it this time. The police were there the whole time and the only people arrested were the union thugs. (Atlanta Journal-Constitution -- Opinion)
Sanders shocked by political accusations Aug 7, 2009
Friday August 07, 2009. James Sanders wonders why his rivals question his closeness to Mayor Mike Bloomberg. (Queens Chronicle, NY)
Big Chance for Young Receivers Aug 7, 2009
MJ has the size and talents to turn it up a notch. Right now if TD stands pat and does not go rush out and sign a WR, the best case scenario for ATL would be for MJ to grab hold of the #1, and Bergeron to step up to the #2. (Atlanta Journal-Constitution -- Sports)
Stem Cell 'Daughters' Lead To Breast Cancer Aug 5, 2009
4, 2009) Walter and Eliza Hall Institute scientists have found that a population of breast cells called luminal progenitor cells are likely to be responsible for breast cancers that develop in women carrying mutations in the gene BRCA1. BRCA1 gene mutations are found in 10-20 per cent of women with hereditary breast cancer. (Science Daily)
The Legend of Tyler Hansbrough Aug 3, 2009
" That doesnt mean hes always easy to live with. I call him bipolar sometimes, Frasor said, because he'll walk in the door and you don't know whether he's going to be laughing, joking around, or if he's going to be serious, downing his fish oil pills, and going to sleep. Theres no halfway. Youll ask him what he did today, and he says, Nothing, and just sits on the couch, not saying a word. The image of Hansbrough brooding in his apartment is probably not hard to... (InsideCarolina.com)
Tiny village hits El Gordo lottery jackpot Aug 2, 2009
top notch pr consumer and lifestyle consultancy lo. up to 31K + benefits. (Yahoo News -- Gambling & Lottery)
The Hot Button: Will UGA win a BCS title under Mark Richt? Jul 31, 2009
Richt is now focused on not only getting top notch talent, which he is, but on building the team approach it takes to win it all coming out of the SEC he has seen the light by what he has witnessed down in Gainesville (what team chemistry and team focus can do). blackhawk. (Atlanta Journal-Constitution -- Sports)
Marieke Hardy Who smoked enough crack to believe marrying off So You Think You Can Dance to The Biggest Loser was a good idea? Read more Jul 30, 2009
That said, this whole Dance Your Ass Off caper really took things up an entirely unpleasant notch and I think it s time someone sensible stepped in and put a stop to the insanity. Whichever sun-damaged television executive smoked enough crack during their lunch break to believe marrying off So You Think You Can Dance to The Biggest Loser was the mother of all concepts should be taken out to a paddock and beaten with Adam Hills detachable leg til they bleed from the eyeballs. (The Age, Australia)
Senate Panel Approves Sotomayor Jul 29, 2009
Another corrupt notch in Washington. by woeisme1 July 28, 2009 1:31 PM EDT. (CBS News -- Politics)
France's high-octane Sarkozy gets a wakeup call Jul 28, 2009
Under her tutelage, the collapse just might be an excellent excuse for Sarkozy to take his frenetic pace down a notch. (Copyright 2009 by The Associated Press. (WSVN-TV Miami, FL)
Commitments pouring in like its almost February Jul 24, 2009
Keeping top notch competition among all SEC makes us stronger when it comes to bowl time. Good luck. (Atlanta Journal-Constitution -- Sports)
Garrison Smith undeterred by accidental video release Jul 21, 2009
He didn t get a 1280 out of 2400, he got a 1280 out of 1600, which is very impressive for a top-notch athlete ... the real fact is that UGA is a factory for NFl top notch players. (Atlanta Journal-Constitution -- Sports)
Why Neural Stem Cells Divide And Differentiate Jul 18, 2009
On the molecular level receptors of the Notch family play a significant role in this process. So far, only stimulating extracellular ligands of Notch receptors had been described ... Biochemists of Goethe University Medical School now describe a long time assumed but not yet identified soluble Notch inhibitor. (Science Daily)
Zell: Use Gorilla Glue on Obamas chair Jul 17, 2009
As Govenor Zell Miller was just notch above our current Gov. I liked him better when he was Lt. Gov, He s no authority on national matters. St. Mt. Gal. (Atlanta Journal-Constitution -- Metro)
Drama ahead in Big Apple Jul 17, 2009
He's nowhere close to the unhittable strikeout machine of 2007; with his heater down to 90-91 mph, Joba is a notch above ordinary, that's it. Chamberlain belongs back in the bullpen, just as Goose Gossage told the New York Post on Wednesday. (News & Observer -- Sports)
Bomb defuser also a dude Jul 10, 2009
Then Renner kicks it up a notch. Summit Entertainment. (Atlanta Journal-Constitution)
Downtown lunch Jul 9, 2009
Lunch also gives diners a chance to try top-notch restaurants at often significant discounts ... With its gleaming wood floors, lush flower arrangements and silk draperies in grays and blues, Nine on Nine is elegant and opulent even at lunch, when the rarefied atmosphere is taken down a notch. (Pittsburgh Post-Gazette, PA)
The Cost of Living in New Iberia Jul 9, 2009
Da Berry wrote on Jul 7, 2009 9:51 AM:" Overpriced? Why wouldn't people want to live in New Iberia? Great Schools, top notch government, world class law enforcement, excellent job market, low crime, new businesses opening all the time. It is the jewel of the Teche. (insert sarcasm here). You could not pay me enough to live in that city. I enjoy reading New Iberia's local news because it is the only city on earth that can make Abbeville look like Mayberry. ". E. Landry wrote on Jul 5, 2009 8:43... (New Iberia, LA)
Controversial Cancer Stem Cells Offer New Direction For Treatment Jul 7, 2009
For example, pathways known to be important for normal stem cell self-renewal, such as the Wnt, Notch and Hedgehog(Hh) pathways, are now of increased interest due to their potential role in CSCs. The first clinical trial using an agent to block the Notch pathway in combination with chemotherapy for breast cancer has begun. (Science Daily)
10 places to take kids away from everyday Jul 5, 2009
A drop-away view of Crawford Notch provides a long glimpse of what the White Mountains offer, and plenty of terrain to set sights for another day ... Trailhead behind Crawford Depot Information Center, Route 302, Crawford Notch, N.H.. (Boston Globe)
Movie Matters: Instead of smut, Fox should share thoughts of substance Jul 3, 2009
breaktime wrote on Jul 2, 2009 4:37 PM:" Wow Alan, bring it down a notch. Did you even read her article? All she is saying is that Megan Fox has a golden opportunity to do something with her candid voice and she is wasting it on talking about things as frivolous as what the movie companies would have her say. If she is so proud of thinking for herself, why doesn't she ever say anything worth listening too? You say 'it's a shame Ms. Fox's honesty and beauty are lost [on the author]. Did you skip... (Chippewa Falls Chippewa Herald, WI)
Keeping it in perspective: Were talking nationals Jun 26, 2009
Earlier in the big meet, O Loughlin won a silver medal in the Emerging Elite mile a race a notch below the top level and the sprint medley relay team broke the state record which had stood since 1998. But the two biggest things that could have happened didn t.. (Westerly Sun, RI)
Is Obama Too Perfect? Jun 26, 2009
Take it down a notch, dude ... Take it down a notch, dude ... Obama isn't the one that needs to take it down a notch. (CBS News)
Transformers explodes onto the screen, but sizzles out Jun 24, 2009
The filmography and CG in Transformers Revenge of the Fallen is top notch and truly spectacular. For that reason alone you should go see it in theaters. (Rexburg Standard Journal, ID)
Professor, 30, student, 50. Is consensual sex OK? Jun 17, 2009
Another notch in the gun for Pubtard Ectopic Sctuppin. Famlah Values mah butt. (Atlanta Journal-Constitution -- Opinion)
Economic value of Lodi wine industry is $5 billion, study says (806) Jun 17, 2009
Rhodie wrote on Jun 16, 2009 4:33 PM:" Second possibility is the business metting aspect. My wife's firm holds close to a dozen business meetings/celebrations ar a winery a year between the three offices and none of them are in the Lodi area. Conventions and day meetings area a real oppertunity for the right sized winery with a meeting hall, catering options and even some over night accomidations. Again going from what I came from, the nationally (actually internationally since my brother in-law... (Lodi News Sentinel, CA)
Lung Disease: Top Notch Decisions In The Developing Airways Bring Insights Into Lung Disease Jun 17, 2009
The Notch pathway is a major regulator of cell fate decisions in developing cells from fruit flies to humans. Using mouse genetic models, the BU researchers inactivated Notch signaling in the lung and discovered that airways no longer formed secretory cells ... The researchers showed that this imbalance seems to result from the loss of a mechanism of cell fate choice triggered by the Notch called lateral inhibition. (Science Daily)
Lafayette Newsstand Jun 16, 2009
Fouled on a 3-point attempt that spun out with seven-tenths of a second remaining, Betley saw a second chance to notch three game-tying points go awry when his third foul shot tickled the iron and fell harmlessly to the Kirby Sports Center floor. The Leopards missed seven free throws, but none stung more than the last attempt, which allowed Colgate to escape College Hill with a stunning 76-75 Patriot League victory in the teams' second wild affair in less than a month. (Goleopards.com)
AGA Institute presents cutting-edge research during DDW May 29, 2009
Genetic ablation of the Notch signaling promotes TGF- -induced epithelial-mesenchymal transition involving posttranscriptional regulation of ZEB1 and ZEB2 by microRNA-200 family members. S. Ohashi et al. (8:22 a.m.). (EurekAlert!)
Green Your Grill To Improve Your Health May 27, 2009
Looking to do some serious grilling and want to take your game up a notch. Here's some basic grilling tips that can help you do just that. (Click2Houston, TX)
Twins welcome Young back to clubhouse May 25, 2009
Twins righty tosses seven scoreless innings to notch victory. Minnesota (21-23) vs. Milwaukee (26-17), 7:05 p.m. CT. (MLB.com -- Minnesota Twins)
The lessons to be learned from Pahokee-Gate May 22, 2009
He came into the game very late, has an excellent recruiting year (all things considered), has assembled a top notch coaching staff, and is constantly in the news ... Lane Kiffen did not hire a top notch coaching staff, he hired a top notch recruiting staff. (Atlanta Journal-Constitution -- Sports)
Cancer Stem Cells May Be Related To Prognosis In Primary Breast Cancer May 22, 2009
Of the bone marrows collected, 61 were analyzed for estrogen receptor and HER-2 status, as well as expression of the transcription factor Notch-1 ... The researchers also found the level of Notch-1 was lower in neoadjuvant treated patients and inversely correlated between the level of its expression and the percentage of breast cancer stem cells, suggesting that Notch signaling may play an integral role in the development of breast cancer stem cells ... Also, based on these initial findings, a... (Science Daily)
Immunohistochemistry Tests Distinguish Breast Cancer Subtypes May 19, 2009
This discovery indicates the mechanism by which inappropriate expression of the notch pathway may. . (Science Daily)
Chrysler Seeks To Slash 789 Dealerships May 15, 2009
This place is a notch above the now defunct Weekly World News. Posted by cmc1227 at 5:18 PM : May 14, 2009. (CBS News)
Lodi City Council approves Wal-Mart Supercenter by 3-2 vote (1836) May 15, 2009
I thought you wanted to keep the quality of life a notch above the rest. I thought this was going to be a place where my kids could grow up as kids. (Lodi News Sentinel, CA)
Bristol is brave May 12, 2009
" roughneck wrote on May 8, 2009 7:37 AM:" bristol is just another notch on the welfare sapping single mommie trend,and the valley is full of them lazy welfare queens. " WRITE A COMMENT Use the form below to post a brief comment to this story, or respond to other readers. Please use the word count tool to assist you in keeping your remarks to 100 words or fewer. Comments must be approved by an editor before appearing on the Web site. Editors review submitted comments periodically during the day... (Wasilla Frontiersman, AK)
Clutch seventh sparks Braves' victory May 11, 2009
Kawakami produced six solid innings and then notched his first win in a span of five starts with the help of Casey Kotchman ... After Gonzalez worked a scoreless eighth, Rafael Soriano, who began the 2008 season as the Braves' closer, was given a chance to face two right-handers before dealing with the switch-hitting duo of Jimmy Rollins and Shane Victori 0000149B no. Miguel Cairo's bloop leadoff single was the only thing that delayed the scoreless ninth that Soriano manufactured to notch his... (MLB.com -- Atlanta Braves)
How to measure a fish May 7, 2009
When Jeremy Wiser hauled my fish into the boat and laid it along his measuring gunnel, his buddy Steve said, "Here's what you do. You take your knife and carve a notch in the boat right there and you say, 'This is the length to beat!'". Smith Mountain Lake, site of the last Bassmaster Elite Series tournament, is home to muskellunge. (ESPN -- Outdoors)
